Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shijun Kang"'
Autor:
Zike Yang, Yanxia Qi, Nan Lai, Jiahe Zhang, Zehong Chen, Mingyu Liu, Wan Zhang, Rongcheng Luo, Shijun Kang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)
Abstract Background The receptors of Notch family play an important role in controlling the development, differentiation, and function of multiple cell types. The aim of this study is to investigate the role of Notch1 signaling upon immune suppressio
Externí odkaz:
https://doaj.org/article/c4349407d9de42d184ab27af30fb5023
Publikováno v:
Immunology Letters. 250:15-22
Adoptive transfer of PD-1 knockout T cells mediated by CRISPR/Cas9 technology has been used in various cancers and got satisfactory treatment effectiveness. However, the effectiveness was limited due to the low proliferation ability, antigen recognit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f074052e0e22bd53aa0ea9d7f52330d1
https://doi.org/10.1016/j.imlet.2022.09.004
https://doi.org/10.1016/j.imlet.2022.09.004
Publikováno v:
Nan Fang Yi Ke Da Xue Xue Bao
OBJECTIVE: To investigate whether interleukin-12 (IL-12) over-expression in malignant melanoma B16 cells affects the expression level of programmed death-1 (PD-1) on T cells in mice during immune microenvironment reconstruction. METHODS: B16 cells we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9f727accceb412d1b1eaa592e3016dc7
https://pubmed.ncbi.nlm.nih.gov/32895201
https://pubmed.ncbi.nlm.nih.gov/32895201
Background Lymphopenic condition after radiotherapy or chemotherapy might be able to create an environment to mount an efficient antitumor immunity through the homeostatic proliferation of residual or adoptive lymphocytes. However, the antitumor immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d1ce995c91238e356b41308c5e5fff7
https://doi.org/10.21203/rs.3.rs-25668/v1
https://doi.org/10.21203/rs.3.rs-25668/v1
Autor:
Jiexia Zhang, Linlang Guo, Weiliang Zhu, Peng Luo, Xin Chen, Anqi Lin, Ningning Zhou, Jian Zhang, Huojin Deng, Shijun Kang
Publikováno v:
Cancer immunology, immunotherapy : CII. 70(1)
To date, immunotherapy has opened a new chapter in the treatment of lung cancer. Precise biomarkers can help to screen subpopulations of lung cancer to provide the best treatment. Multiple studies suggest that specific gene mutations may be predictiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f016b97941364120d1f81800997c2db
https://pubmed.ncbi.nlm.nih.gov/32653938
https://pubmed.ncbi.nlm.nih.gov/32653938
Publikováno v:
Cancer Science
Stomatin‐like protein 2 (STOML2 or SLP‐2) is an oncogenic anti‐apoptotic protein that is upregulated in several types of cancer, including cervical cancer. However, the mechanisms responsible for the SLP‐2 anti‐apoptotic function remain poo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1825443fdbf937b863347f53db826cbc
https://doi.org/10.1111/cas.13563
https://doi.org/10.1111/cas.13563
Publikováno v:
Cancer science. 109(6)
Various types of vaccines have been proposed as approaches for prevention or delay of the onset of cancer by boosting the endogenous immune system. We previously developed a senescent-cell-based vaccine, induced by radiation and veliparib, as a preve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abab105f9054c18158eceb28ab7a746f
https://pubmed.ncbi.nlm.nih.gov/29675979
https://pubmed.ncbi.nlm.nih.gov/29675979
OBJECTIVE: To investigate whether soluble PD-1 overexpression in 4T1 senescence tumor cells enhances the antitumor effect of senescence tumor cell vaccine (STCV) against breast tumor cells in a tumor-bearing mouse model. METHODS: 4T1 cells were treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5249e40a956d942bc5a6d2e0d48b3c7e
https://europepmc.org/articles/PMC6765615/
https://europepmc.org/articles/PMC6765615/
Autor:
Rongcheng Luo, Zehong Chen, Wan Zhang, Zike Yang, Yanxia Qi, Mingyu Liu, Nan Lai, Shijun Kang, Jiahe Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)
Background The receptors of Notch family play an important role in controlling the development, differentiation, and function of multiple cell types. The aim of this study is to investigate the role of Notch1 signaling upon immune suppression induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebe27e1c3a8da56ce28a6c8a4f7db85
https://doi.org/10.1186/s13046-017-0664-4
https://doi.org/10.1186/s13046-017-0664-4
Autor:
Peter Pytel, Giovanna M. Bernal, Nassir Mansour, Shijun Kang, Gustavo Larsen, Michael J. LaRiviere, Bakhtiar Yamini, Ulrich Welp, Sandra Noriega, Luis Nunez, David J. Voce, Kirk E. Cahill, Ruben Spretz, Ralph R. Weichselbaum
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 10:149-157
A major obstacle to the management of malignant glioma is the inability to effectively deliver therapeutic agent to the tumor. In this study, we describe a polymeric nanoparticle vector that not only delivers viable therapeutic, but can also be track
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41300ae6a983a22972ef1aac1bc5244
https://doi.org/10.1016/j.nano.2013.07.003
https://doi.org/10.1016/j.nano.2013.07.003