Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shijing Qian"'
Publikováno v:
Advances in Clinical & Experimental Medicine; Apr2023, Vol. 32 Issue 4, p423-432, 10p
Autor:
Lulu Tian, Jing Wang, Zhan Qi, Shijing Qian, Danfei Song, Beilei Chen, Deqiu Zhu, Sha Zhang, Shanshan Tong, Juan Wu
Publikováno v:
Journal of the American Pharmacists Association : JAPhA. 62(2)
BACKGROUND There is a lack of research on the nature of drug-related problems (DRPs) in older adult communities in China and the impact of home medication review on DRP reduction and health-related quality-of-life (HRQoL) improvement. OBJECTIVES To i
Paris saponin VII extracted from Trillium tschonoskii induces autophagy and apoptosis in NSCLC cells
Publikováno v:
Journal of Ethnopharmacology. 248:112304
Ethnopharmacological relevance Trillium tschonoskii Maxim, a perennial herb of the Trilliaceae, has been widely used to treat inflammation, hypertension and cancer. We investigated Paris saponin VII's (PS VII), isolated from Trillium tschonoskii Maxi
Autor:
Si-Da Liao, Yongzhou Hu, Li Wang, Ji Cao, Xiaochun Yang, Shijing Qian, Hong Zhu, Qiaojun He, Bo Yang
Publikováno v:
Translational Oncology, Vol 6, Iss 1, Pp 75-82 (2013)
A novel VP-16 derivative, 4β-[N -(4‴-acetyloxyl-phenyl-1‴-carbonyl)-4″-aminoanilino]-4′-O-demethyl-4-desoxypodophyllotoxin (GL3), displayed a wide range of cytotoxicity in a panel of human tumor cell lines, with half-maximal inhibitory conce
Publikováno v:
Molecular and Cellular Biochemistry. 345:13-21
N-(2-(1H-indazol-3-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl)-4-chloro-N-methylbenzamide (SMT-A07) is a novel 3-(Indol-2-yl) indazole derivative. The anticancer activities in vitro and the cell apoptosis-induction abilities of SMT-A07 on human leukemia HL60
Autor:
Danqing Xu, Lin Li, Yongzhou Hu, Hong Zhu, Bo Yang, Ji Cao, Difeng Zhu, Qinjie Weng, Qiaojun He, Chunqi Hu, Jianshu Lou, Shijing Qian
Publikováno v:
Investigational New Drugs. 29:786-799
Etoposide (VP-16), a topoisomerase II (Topo II) inhibitor, has been widely used to treat malignancies. Its clinical application, however, has been hindered by the rise of acquired multidrug resistance (MDR). Here, we report that 4β-{[4-(pyrrolidin-1
Publikováno v:
ChemInform. 42
The novel title derivatives are synthesized in order to test their in vitro antitumor activity against SMMC-7721 and A549 cell lines in comparison to taxol.
Publikováno v:
European journal of medicinal chemistry. 46(1)
A novel kind of thiazolylbenzimidazole derivatives were designed and synthesized and evaluated for their antitumor activity against SMMC-7721 and A549 cell lines. Most compounds showed good antitumor activities, and compound 11b displayed remarkable
Autor:
Yongzhou Hu, Danqing Xu, Wenting Du, Shijing Qian, Bo Yang, Chunqi Hu, Jianshu Lou, Li Wang, Qiaojun He
Publikováno v:
Molecular bioSystems. 6(2)
A new series of 4 beta-anilino-podophyllotoxin analogs have been designed, synthesized and evaluated their bioactivities as novel DNA-topoisomerase II poisons as well as P-glycoprotein (P-gp)-dependent multidrug resistance (MDR) inhibitors. The new c
Publikováno v:
Organic & Biomolecular Chemistry. 10:3189
A mechanism-based small molecular fluorescent probe has been developed to label active O(6)-methylguanine-DNA methyltransferase in live cells.