Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Shiji, Varghese"'
Autor:
Zitianyu Wang, Victoria Lewis, Christiane Stehmann, Shiji Varghese, Matteo Senesi, Amelia McGlade, Laura J. Ellett, James D. Doecke, Dhamidhu Eratne, Dennis Velakoulis, Colin L. Masters, Steven J. Collins, Qiao‐Xin Li
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract Most suspected Creutzfeldt‐Jakob disease (CJD) cases are eventually diagnosed with other disorders. We assessed the utility of investigating Alzheimer's disease (AD) biomarkers and neurofilament light (NfL) in patients when CJD is suspecte
Externí odkaz:
https://doaj.org/article/bb39afaf574a49de915fe1b741f84a76
Autor:
Matteo Senesi, Victoria Lewis, Shiji Varghese, Christiane Stehmann, Amelia McGlade, James D. Doecke, Laura Ellett, Shannon Sarros, Christopher J. Fowler, Colin L. Masters, Qiao-Xin Li, Steven J. Collins
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
The most frequently utilized biomarkers to support a pre-mortem clinical diagnosis of sporadic Creutzfeldt–Jakob disease (sCJD) include concentrations of the 14-3-3 and total tau (T-tau) proteins, as well as the application of protein amplification
Externí odkaz:
https://doaj.org/article/ffbd11a8aac9450a99838a1447b1e0aa
Autor:
Matthew J. Y. Kang, Dhamidhu Eratne, Hannah Dobson, Charles B. Malpas, Michael Keem, Courtney Lewis, Jasleen Grewal, Vivian Tsoukra, Christa Dang, Ramon Mocellin, Tomas Kalincik, Alexander F. Santillo, Henrik Zetterberg, Kaj Blennow, Christiane Stehmann, Shiji Varghese, Qiao-Xin Li, Colin L. Masters, Steven Collins, Samuel F. Berkovic, Andrew Evans, Wendy Kelso, Sarah Farrand, Samantha M. Loi, Mark Walterfang, Dennis Velakoulis
Publikováno v:
Acta Neuropsychiatrica. :1-12
Objective: People with neuropsychiatric symptoms often experience delay in accurate diagnosis. Although cerebrospinal fluid neurofilament light (CSF NfL) shows promise in distinguishing neurodegenerative disorders (ND) from psychiatric disorders (PSY
Autor:
Soumya Mukherjee, Celine Dubois, Keyla Perez, Shiji Varghese, Ian E. Birchall, Miranda Leckey, Natalia Davydova, Catriona McLean, Rebecca M. Nisbet, Blaine R. Roberts, Qiao‐Xin Li, Colin L. Masters, Victor A. Streltsov
Publikováno v:
Journal of Neurochemistry. 164:529-552
The two hallmarks of Alzheimer's disease (AD) are amyloid-β (Aβ) plaques and neurofibrillary tangles marked by phosphorylated tau. Increasing evidence suggests that aggregating Aβ drives tau accumulation, a process that involves synaptic degenerat
Autor:
Victor A Streltsov, Shiji Varghese, Soumya Mukherjee, Liang Jin, Catriona McLean, Blaine R. Roberts, Ian Birchall, Celine Dubois, Colin L. Masters, Qiao-Xin Li, Kevin J Barham, Rebecca M Nisbet, Laura J Vella, Keyla Perez
Publikováno v:
ACS Chemical Neuroscience. 12:3719-3732
Protein citrullination (deimination of arginine residue) is a well-known biomarker of inflammation. Elevated protein citrullination has been shown to colocalize with extracellular amyloid plaques in postmortem AD patient brains. Amyloid-β (Aβ) pept
Autor:
Nirbaanjot Walia, Dhamidhu Eratne, Samantha M. Loi, Sarah Farrand, Qiao‐Xin Li, Charles B. Malpas, Shiji Varghese, Mark Walterfang, Andrew H. Evans, Shaun Parker, Steven J. Collins, Colin L. Masters, Dennis Velakoulis
Publikováno v:
Internal Medicine Journal.
Neurodegeneration underpins the pathological processes of younger-onset dementia (YOD) and has been implicated in primary psychiatric disorders (PSYs). Cerebrospinal fluid (CSF) neurofilament light (NfL) has been used to investigate neurodegeneration
Autor:
Matthew Kang, Dhamidhu Eratne, Hannah Dobson, Charles B Malpas, Michael Keem, Courtney Lewis, Jasleen Grewal, Vivian Tsoukra, Christa Dang, Ramon Mocellin, Tomas Kalincik, Alexander F Santillo, Henrik Zetterberg, Kaj Blennow, Christiane Stehmann, Shiji Varghese, Qiao-Xin Li, Colin L Masters, Steven Collins, Samuel F Berkovic, Andrew Evans, Wendy Kelso, Sarah Farrand, Samantha M Loi, Mark Walterfang, Dennis Velakoulis
ObjectivePeople with neuropsychiatric symptoms often experience delay in accurate diagnosis. Although cerebrospinal fluid neurofilament light (CSF NfL) shows promise in distinguishing neurodegenerative disorders (ND) from psychiatric disorders (PSY),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::101f5f7053c28c9e22241443f9547965
https://doi.org/10.1101/2022.09.08.22279663
https://doi.org/10.1101/2022.09.08.22279663
Autor:
Ying Xia, Vincent Dore, Victor L. Villemagne, Brendan S. Silbert, Jurgen Fripp, James D. Doecke, Elise J Harrison, Adrian Kamer, Robert Grenfell, Madeline Peretti, Simon McBride, Christopher C. Rowe, Paul Maruff, Lidija Milicic, Kelly K. Pertile, Steven J. Collins, Tania Taddei, Christine Thai, Andrea G. Louey, Michael Weinborn, Richard Head, Pierrick Bourgeat, Colin L. Masters, Olivier Salvado, Sabine Bird, S. Lance Macaulay, Rebecca L. Rumble, Michael Vacher, Simon Gibson, Lucy Lim, Amir Fazlollahi, Samantha C. Burnham, Kathryn A. Ellis, Yen Ying Lim, Regan Tyrrell, Julia Bomke, Michael Woodward, Belinda M. Brown, Joanne Robertson, Brett Trounson, Simon M. Laws, Carolyn Chadunow, Magdalene Soh, Liang Jin, Morgan Radler, Greg Savage, Christopher Fowler, Ralph N. Martins, Samantha L. Gardener, Fiona Lamb, Mark Rodrigues, Lucy Mackintosh, David Ames, Stephanie R. Rainey-Smith, Lis Evered, Alan Rembach, Tenielle Porter, Qiao-Xin Li, Nicola T. Lautenschlager, Shiji Varghese, Ashley I. Bush, Hamid R. Sohrabi, Kevin Taddei
Publikováno v:
Journal of Alzheimer's Disease Reports
Background: The Australian Imaging, Biomarkers and Lifestyle (AIBL) Study commenced in 2006 as a prospective study of 1,112 individuals (768 cognitively normal (CN), 133 with mild cognitive impairment (MCI), and 211 with Alzheimer’s disease dementi
Autor:
Soumya Mukherjee, Celine Dubois, Keyla Perez, Rebecca M Nisbet, Qiao‐Xin Li, Shiji Varghese, Larissa Cristina Lago, Stephan Klatt, Ian Birchall, Liang Jin, Catriona McLean, Victor Streltsov, Kevin J Barnham, Laura J Vella, Colin L Masters
Publikováno v:
Alzheimer's & Dementia. 17
Autor:
Dhamidhu, Eratne, Samantha M, Loi, Qiao-Xin, Li, Christiane, Stehmann, Charles B, Malpas, Alexander, Santillo, Shorena, Janelidze, Claire, Cadwallader, Nirbaanjot, Walia, Blair, Ney, Victoria, Lewis, Matteo, Senesi, Christopher, Fowler, Amelia, McGlade, Shiji, Varghese, Parsa, Ravanfar, Wendy, Kelso, Sarah, Farrand, Michael, Keem, Matthew, Kang, Anita M Y, Goh, Kunal, Dhiman, Veer, Gupta, Rosie, Watson, Nawaf, Yassi, Cath, Kaylor-Hughes, Richard, Kanaan, Piero, Perucca, Hannah, Dobson, Lucy, Vivash, Rashida, Ali, Terence J, O'Brien, Oskar, Hansson, Henrik, Zetterberg, Kaj, Blennow, Mark, Walterfang, Colin L, Masters, Samuel F, Berkovic, Steven, Collins, Dennis, Velakoulis
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES. 18(11)
Many patients with cognitive and neuropsychiatric symptoms face diagnostic delay and misdiagnosis. We investigated whether cerebrospinal fluid (CSF) neurofilament light (NfL) and total-tau (t-tau) could assist in the clinical scenario of differentiat