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Akademický článek

Comparison of properties determined using electromechanical assessment (Arthro-BST™) with macroscopic and histological properties in symptomatic human articular cartilage of the hip

Autor: Taku Ukai, Masato Sato, Shiho Wasai, Takumi Takahashi, Haruka Omura, Masahiko Watanabe

Publikováno v: Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)

Abstract Background Cartilage degeneration is assessed using various methods. Although macroscopic evaluation can directly measure cartilage degeneration, it cannot accurately assess cartilage properties. Histological examination is one of the most a

Externí odkaz: https://doaj.org/article/a40b659f020643d09c221088bc449561

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Comparison of properties determined using electromechanical assessment (Arthro-BST™) with macroscopic and histological properties in symptomatic human articular cartilage of the hip

Autor: Haruka Omura, Takumi Takahashi, Masato Sato, Taku Ukai, Masahiko Watanabe, Shiho Wasai

Publikováno v: Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)

Background Cartilage degeneration is assessed using various methods. Although macroscopic evaluation can directly measure cartilage degeneration, it cannot accurately assess cartilage properties. Histological examination is one of the most accurate m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f2a9629cb124169b6118768582f8fe
http://europepmc.org/articles/PMC8406846

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Development of Injectable Polydactyly-Derived Chondrocyte Sheets

Autor: Takumi Takahashi, Masahiko Watanabe, Eri Okada, Miki Maehara, Eriko Toyoda, Masato Sato, Shiho Wasai, Ryoka Uchiyama, Tadashi Akamatsu

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 3198, p 3198 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 6

We are conducting a clinical study of the use of allogeneic polydactyly-derived chondrocyte sheets (PD sheets) for the repair of articular cartilage damage caused by osteoarthritis. However, the transplantation of PD sheets requires highly invasive s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40079150a15a1583d2072b44debb9523
https://www.mdpi.com/1422-0067/22/6/3198

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Effect of Platelet-Rich Plasma on M1/M2 Macrophage Polarization

Autor: Shiho Wasai, Masahiko Watanabe, Haruka Omura, Miki Maehara, Masato Sato, Ryoka Uchiyama, Eriko Toyoda

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 5
International Journal of Molecular Sciences, Vol 22, Iss 2336, p 2336 (2021)

Osteoarthritis of the knee (OAK) is a chronic degenerative disease and progresses with an imbalance of cytokines and macrophages in the joint. Studies regarding the use of platelet-rich plasma (PRP) as a point-of-care treatment for OAK have reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73de7b06ff0ad35862b96267ee0a926f

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Characteristics of autologous protein solution and leucocyte-poor platelet-rich plasma for the treatment of osteoarthritis of the knee

Autor: Masahiko Watanabe, Satoko Suzuki, Takumi Takahashi, Eriko Toyoda, Miki Maehara, Eri Okada, Yoshiko Iwasaki, Shiho Wasai, Ryoka Uchiyama, Masato Sato

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)

Recently, platelet-rich plasma (PRP) has received attention as a treatment for patients with osteoarthritis of the knee (OAK), a chronic degenerative disease, to bridge the gap between conservative and surgical treatments. Here, we investigated the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7b932fe1aa056e422b2b7401d1500a
https://doi.org/10.1038/s41598-020-67099-y

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Transcriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration

Autor: Ken Nonaka, Takumi Takahashi, Masahiko Watanabe, Masato Sato, Eri Okada, Shiho Wasai, Miki Maehara, Eriko Toyoda, Hiroshi Iijima, Yuka Kawaguchi

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 1, p 149 (2019)
International Journal of Molecular Sciences
Volume 21
Issue 1

Chondrocyte sheet transplantation is a novel and promising approach to treating patients who have cartilage defects associated with osteoarthritis. Hyaline cartilage regeneration by autologous chondrocyte sheets has already been demonstrated in clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa6ab110ebda231c1b94a43b56b5a1d
https://www.mdpi.com/1422-0067/21/1/149

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