Výsledky vyhledávání - "Shiho Mifune"

Dependence of Hydrolysis of .BETA.-Lactams with a Zinc(II)-.BETA.-Lactamase Produced from Serratia marcescens (IMP-1) on pH and Concentration of Zinc(II) Ion: Dissociation of Zn(II) from IMP-1 in Acidic Medium

Autor: Kumiko Harada, Hiromasa Mori, Yoshihiro Yamaguchi, Akiko Kawanami, Hitoshi Nakayama, Hisami Yasuzawa, Shiho Mifune, Masafumi Goto, Yoshichika Arakawa, Toshihiro Higashi

Publikováno v: Biological and Pharmaceutical Bulletin. 26:589-594

The pH dependence for the hydrolysis of beta-lactam antibiotics by a metallo-beta-lactamase (IMP-1) produced from Serratia marcescens was investigated varying the concentration of Zn(II). The activity of IMP-1 for imipenem was decreased at pH less th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2e6a45f4e6b90b46451bda8124deaa
https://doi.org/10.1248/bpb.26.589

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