Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Shiho Futaki"'
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 107:850-859
The purpose of this study was to determine the role of ventricular size or contractility in the effectiveness of dynamic cardiac compression in terms of the pressure-volume relationship and myocardial oxygen consumption. In 10 isolated cross-circulat
Autor:
T W Taylor, Osamu Kawaguchi, Toshiyuki Takasago, Akio Saeki, Shiho Futaki, Yoichi Goto, Katsuya Hata, Hitoshi Yaku, Yuichi Ohgoshi, Takehiko Nishioka
Publikováno v:
Circulation. 86:1291-1301
BACKGROUND We hypothesized that the effect of pimobendan (UD-CG 115 BS) to increase calcium sensitivity of contractile protein might result in less myocardial oxygen consumption (VO2) in comparison with dobutamine when they enhance ventricular contra
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 104:364-373
We studied the effects of cardiac hypothermia on myocardial oxygen consumption of a fibrillating ventricle and evaluated whether myocardial oxygen consumption of a fibrillating ventricle in hypothermia can be accounted for by new mechanical indexes:
Autor:
Yuichi Ohgoshi, Shiho Futaki, Katsuya Hata, Yoichi Goto, Hitoshi Yaku, Hiroyuki Suga, Toshiyuki Takasago, Osamu Kawaguchi
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 262:H1734-H1743
We have recently proposed a mechanical index, equivalent pressure-volume (PV) area (ePVA), as a measure of the total mechanical energy during ventricular fibrillation (VF). ePVA, an analogue of the PV area (PVA) of a beating heart, is the area surrou
Autor:
Osamu Kawaguchi, Akio Saeki, Toshiyuki Takasago, Yoichi Goto, Takehiko Nishioka, Katsuya Hata, Yuichi Ohgoshi, Hitoshi Yaku, Tad W. Taylor, Shiho Futaki, Hiroyuki Suga
Publikováno v:
Heart and Vessels. 7:57-65
We propose new indexes to evaluate the effects of ventricular inotropism and lusitropism on stroke volume. The end-systolic pressure-volume relationship (ESPVR) or its slope (Emax) has been employed to assess ventricular inotropism. The end-diastolic
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 103:514-520
We studied whether ventricular fibrillation depresses ventricular contractility in a blood-perfused heart. In 12 excised, cross-circulated dog hearts, we measured left ventricular pressure and myocardial oxygen consumption at a middle left ventricula
Publikováno v:
Heart and Vessels. 7:8-17
The effects of DPI 201-106 (a novel, cyclic AMP-independent positive inotropic agent with Ca(2+)-sensitizing and Na(+)-channel agonistic mechanisms) on myocardial mechanics and energetics were assessed in the excised cross-circulated dog left ventric
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 261:H1534-H1544
We attempted to find cardiac mechanical parameters to account for myocardial O2 consumption (VO2) during ventricular fibrillation (VF). We fully utilized the concept of pressure-volume (P-V) area (PVA), which is equivalent to the total mechanical ene
Publikováno v:
Circulation Research. 69:975-988
Recent studies have shown that myocardial oxygen consumption does not proportionally decrease with the deterioration of contractile function in stunned myocardium. To investigate this disproportion, we studied the end-systolic pressure-volume relatio
Autor:
Hiroyuki Suga, Hideo Kusuoka, Takenobu Kamada, Shiho Futaki, Akira Kitabatake, Yukihiro Koretsune, Michitoshi Inoue
Publikováno v:
Journal of Cardiovascular Pharmacology. 18:437-444
To elucidate the mechanism of acute contractile failure induced by adriamycin, the intracellular concentrations of free calcium ([Ca2+]i) and energy-related phosphate compounds were determined in isolated ferret hearts. The time-averaged [Ca2+]i was