Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Shiho, Nakamura"'
Autor:
Chris Kato, Koji Ueda, Satoru Morimoto, Shinichi Takahashi, Shiho Nakamura, Fumiko Ozawa, Daisuke Ito, Yugaku Daté, Kensuke Okada, Naoki Kobayashi, Jin Nakahara, Hideyuki Okano
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-18 (2024)
Abstract Background Extracellular vesicles (EVs) hold the potential for elucidating the pathogenesis of amyotrophic lateral sclerosis (ALS) and serve as biomarkers. Notably, the comparative and longitudinal alterations in the protein profiles of EVs
Externí odkaz:
https://doaj.org/article/166542d458c04fcaa788a27b67f26db5
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 5, Pp 587-588 (2024)
Externí odkaz:
https://doaj.org/article/b812e6ce861a496084f10000f855bbc6
Autor:
Emi Qian, Masahiro Uemura, Hiroya Kobayashi, Shiho Nakamura, Fumiko Ozawa, Sho Yoshimatsu, Mitsuru Ishikawa, Osamu Onodera, Satoru Morimoto, Hideyuki Okano
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-10 (2023)
Abstract Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is an inherited cerebral small vessel disease (CSVD) caused by biallelic mutations in the high-temperature requirement serine peptidase A1
Externí odkaz:
https://doaj.org/article/f2d5916618a74664bb6b7b4455d350a4
Autor:
Nicolas Leventoux, Satoru Morimoto, Kenju Hara, Shiho Nakamura, Fumiko Ozawa, Shio Mitsuzawa, Tetsuya Akiyama, Ayumi Nishiyama, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Hideyuki Okano
Publikováno v:
Stem Cell Research, Vol 47, Iss , Pp 101896- (2020)
Amyotrophic Lateral Sclerosis is the most common motor neuron degenerative disease in adults, and TARDBP gene mutations have been reported to be involved in the pathogenesis. We present here how we generated the human induced pluripotent stem cell (h
Externí odkaz:
https://doaj.org/article/0fef719d79ce4b98ac14b36800e2a90c
SummaryThis study presents a newly developed method to rapidly and efficiently induce human spinal lower motor neurons (LMNs) from induced pluripotent stem cells (iPSCs) for elucidation of the amyotrophic lateral sclerosis (ALS) pathomechanism and dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9950f8ea0451b1720438450436674eb7
https://doi.org/10.1101/2023.04.18.537412
https://doi.org/10.1101/2023.04.18.537412
Publikováno v:
Endoscopy. 55:E682-E683
Autor:
Yasuaki Ikuno, Koichiro Watanabe, Yumi Kakeya, Shinsuke Ikeno, Toshimasa Nakabo, Ayano Narumoto, Yukie Kande, Tomoki Hayashi, Kahori Minami, Kasumi Nobuhiro, Yo Mabuchi, Shiho Nakamura, Hideyuki Okano, Dai Ihara, Hayato Naka-Kaneda
Molecular mechanisms of aging specific to each stem cell (SC) are being elucidated. However, the common molecular basis for senescence in various SCs remains largely unexplored. Here, we have shown that the dysregulation of DNA damage response (DDR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f19f5848acbf5e87290fd297759bb21e
https://doi.org/10.21203/rs.3.rs-2204556/v3
https://doi.org/10.21203/rs.3.rs-2204556/v3
Autor:
Satoru Morimoto, Koichi Saeki, Masaru Takeshita, Kunio Hirano, Mariko Shirakawa, Yumiko Yamada, Shiho Nakamura, Fumiko Ozawa, Hideyuki Okano
Publikováno v:
Genes to cells : devoted to molecularcellular mechanismsREFERENCES.
The coronavirus disease 2019 (COVID-19) epidemic remains worldwide. The usefulness of the intranasal vaccine and boost immunization against severe acute respiratory syndrome-related coronavirus (SARS-CoV-2) has recently received much attention. We de
Autor:
Satoru Morimoto, Mitsuru Ishikawa, Hirotaka Watanabe, Miho Isoda, Masaki Takao, Shiho Nakamura, Fumiko Ozawa, Yoshifumi Hirokawa, Shigeki Kuzuhara, Hideyuki Okano, Yasumasa Kokubo
Publikováno v:
Antioxidants, Vol 9, Iss 5, p 423 (2020)
Amyotrophic lateral sclerosis and Parkinsonism-dementia complex (ALS/PDC) is a unique endemic neurodegenerative disease, with high-incidence foci in Kii Peninsula, Japan. To gather new insights into the pathological mechanisms underlying Kii ALS/PDC,
Externí odkaz:
https://doaj.org/article/df8e4df2bfdb4506acbcc2759e8de29f
Autor:
Ryoichi Nakamura, Genki Tohnai, Masahiro Nakatochi, Naoki Atsuta, Hirohisa Watanabe, Daisuke Ito, Masahisa Katsuno, Akihiro Hirakawa, Yuishin Izumi, Mitsuya Morita, Takehisa Hirayama, Osamu Kano, Kazuaki Kanai, Nobutaka Hattori, Akira Taniguchi, Naoki Suzuki, Masashi Aoki, Ikuko Iwata, Ichiro Yabe, Kazumoto Shibuya, Satoshi Kuwabara, Masaya Oda, Rina Hashimoto, Ikuko Aiba, Tomohiko Ishihara, Osamu Onodera, Toru Yamashita, Koji Abe, Kouichi Mizoguchi, Toshio Shimizu, Yoshio Ikeda, Takanori Yokota, Kazuko Hasegawa, Fumiaki Tanaka, Kenji Nakashima, Ryuji Kaji, Jun-ichi Niwa, Manabu Doyu, Chikashi Terao, Shiro Ikegawa, Koki Fujimori, Shiho Nakamura, Fumiko Ozawa, Satoru Morimoto, Kazunari Onodera, Takuji Ito, Yohei Okada, Hideyuki Okano, Gen Sobue
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. :jnnp-2022
BackgroundSeveral genetic factors are associated with the pathogenesis of sporadic amyotrophic lateral sclerosis (ALS) and its phenotypes, such as disease progression. Here, in this study, we aimed to identify the genes that affect the survival of pa