Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Shihan, He"'
Publikováno v:
BMJ Open, Vol 14, Iss 5 (2024)
Introduction Cardiopulmonary complications and cognitive impairment following craniotomy have a significantly impact on the general health of individuals with brain tumours. Observational research indicates that engaging in walking is linked to bette
Externí odkaz:
https://doaj.org/article/86740d66a2a14026b4943bd9a6783e07
Autor:
Felicia Gray, Hyo Je Cho, Shirish Shukla, Shihan He, Ashley Harris, Bohdan Boytsov, Łukasz Jaremko, Mariusz Jaremko, Borries Demeler, Elizabeth R. Lawlor, Jolanta Grembecka, Tomasz Cierpicki
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
BMI1, a core element of the polycomb repressive complex 1, is suggested to have oncogenic activity in a variety of cancers. Here, the authors report the structure of BMI1 bound to the protein PHC2, identify BMI1 homo-oligomerization interfaces, and a
Externí odkaz:
https://doaj.org/article/73f8f5efb05f424ba5d871afa61e0222
Autor:
Trupta Purohit, EunGi Kim, Mariusz Jaremko, Joshua M Ray, Hyo Je Cho, Shihan He, Hongzhi Miao, Felicia Gray, Caroline Nikolaidis, Łukasz Jaremko, Tomasz Cierpicki, Qingjie Zhao, Weijiang Ying, Jolanta Grembecka, Xiaotian Zhang, Monica L. Guzman, Shirish Shukla, Alyssa Winkler, Yao Yiwu, Jingya Wang, Russell J.H. Ryan, Paula González-Alonso, Juliano Ndoj, George Lund, Miranda L. Simes
Publikováno v:
Nature chemical biology
Polycomb repressive complex 1 (PRC1) is an essential chromatin-modifying complex that monoubiquitinates histone H2A and is involved in maintaining the repressed chromatin state. Emerging evidence suggests PRC1 activity in various cancers, rationalizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be29ba28e75787c38128d3654fcd1836
https://doi.org/10.1038/s41589-021-00815-5
https://doi.org/10.1038/s41589-021-00815-5
Thresholds Derived From Common Measures in Rat Studies Are Predictive of Liver Tumorigenic Chemicals
Autor:
J. Christopher Corton, Hisham A. El-Masri, Katharine L Korunes, John P. Rooney, Shihan He, Cari Martini, Jason M. Brown, Ying Liu, Katie Paul-Friedman, Jaleh Abedini
Publikováno v:
Toxicol Pathol
We hypothesized that typical tissue and clinical chemistry (ClinChem) end points measured in rat toxicity studies exhibit chemical-independent biological thresholds beyond which cancer occurs. Using the rat in vivo TG-GATES study, 75 chemicals were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109534ce11b1c5e443c4b8b86111b301
https://doi.org/10.1177/0192623320960412
https://doi.org/10.1177/0192623320960412
Autor:
Diane M. Robins, Marcin Cieslik, Pia Bagamasbad, Elizabeth LaPensee, Shihan He, Steven Kregel, Michele Brogley, Arul M. Chinnaiyan, Yemi Raji
Publikováno v:
Nucleic Acids Research
Androgen receptor (AR) action is a hallmark of prostate cancer (PCa) with androgen deprivation being standard therapy. Yet, resistance arises and aberrant AR signaling promotes disease. We sought compounds that inhibited genes driving cancer but not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea722ccf972fb794d0baeff9ea930f7e
https://doi.org/10.1093/nar/gkaa178
https://doi.org/10.1093/nar/gkaa178
Publikováno v:
Journal of biochemical and molecular toxicologyREFERENCES. 35(11)
Dysfunction of the ubiquitin-proteasome system has been linked to the pathogenesis of a variety of diseases. Proteasome inhibition not only exerts antitumor effects but also affects inflammatory signaling pathways. MG132, a proteasome inhibitor, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5494eeaa1cfa88cc40688d79b42a03a
https://pubmed.ncbi.nlm.nih.gov/34418242
https://pubmed.ncbi.nlm.nih.gov/34418242
Autor:
Shirish, Shukla, Weijiang, Ying, Felicia, Gray, Yiwu, Yao, Miranda L, Simes, Qingjie, Zhao, Hongzhi, Miao, Hyo Je, Cho, Paula, González-Alonso, Alyssa, Winkler, George, Lund, Trupta, Purohit, EunGi, Kim, Xiaotian, Zhang, Joshua M, Ray, Shihan, He, Caroline, Nikolaidis, Juliano, Ndoj, Jingya, Wang, Łukasz, Jaremko, Mariusz, Jaremko, Russell J H, Ryan, Monica L, Guzman, Jolanta, Grembecka, Tomasz, Cierpicki
Publikováno v:
Nature chemical biology. 17(7)
Polycomb repressive complex 1 (PRC1) is an essential chromatin-modifying complex that monoubiquitinates histone H2A and is involved in maintaining the repressed chromatin state. Emerging evidence suggests PRC1 activity in various cancers, rationalizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a253d998755f3560046fc8e6a7b49a1
https://pubmed.ncbi.nlm.nih.gov/34155403
https://pubmed.ncbi.nlm.nih.gov/34155403
Autor:
J. Christopher Corton, Korunes, Katharine L., Abedini, Jaleh, El-Masri, Hisham, Brown, Jason, Paul-Friedman, Katie, Liu, Ying, Martini, Cari, Shihan He, Rooney, John
Supplemental Material, sj-docx-1-tpx-10.1177_0192623320960412 for Thresholds Derived From Common Measures in Rat Studies Are Predictive of Liver Tumorigenic Chemicals by J. Christopher Corton, Katharine L. Korunes, Jaleh Abedini, Hisham El-Masri, Jas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029d9d68c5b66dead56ed2255a0c7d63
Autor:
J. Christopher Corton, Korunes, Katharine L., Abedini, Jaleh, El-Masri, Hisham, Brown, Jason, Paul-Friedman, Katie, Liu, Ying, Martini, Cari, Shihan He, Rooney, John
Supplemental Material, sj-docx-2-tpx-10.1177_0192623320960412 for Thresholds Derived From Common Measures in Rat Studies Are Predictive of Liver Tumorigenic Chemicals by J. Christopher Corton, Katharine L. Korunes, Jaleh Abedini, Hisham El-Masri, Jas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3796f9b67f8c7693dba6c1a1c640677f
Publikováno v:
Journal of Biochemical & Molecular Toxicology; Nov2021, Vol. 35 Issue 11, p1-8, 8p