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Akademický článek

Ammi majus Seed Extract Cardioprotective Effect Against Doxorubicin Cardiotoxicity in Mice

Publikováno v: Ibn Al-Haitham Journal for Pure and Applied Sciences, Vol 37, Iss 3 (2024)

One of the most efficient anthracycline anti-cancer medications, doxorubicin, is used to treat lymphoid malignancies. Intercalation with deoxyribonucleic acid is a key component of its primary chemotherapeutic mode of action, which can ultimately lea

Externí odkaz: https://doaj.org/article/9c88c7f2116e4b3bb3fa8759dfcc88e4

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Akademický článek

Possible Anti-Asthmatic Effect of Iraqi Ammi Majus Seeds Extract Against Asthma Induced by Ovalbumin in Mice

Autor: Zainab T. Younis, Shihab H. Mutlag

Publikováno v: Iraqi Journal of Pharmaceutical Sciences, Vol 32, Iss Suppl. (2023)

Asthma is a chronic respiratory disorder of airways characterized by inflammation, hyperresponsiveness, inflammatory cell infiltration, mucous secretion, and remodelling. Ammi majus is medicinal plant belong to family of Apiaceous which has anti-infl

Externí odkaz: https://doaj.org/article/6d110018ffa448a1ada55eb6328295b5

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Akademický článek

Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway

Autor: Sarmed H. Kathem, Yasameen Sh. Nasrawi, Shihab H. Mutlag, Surya M. Nauli

Publikováno v: Biomolecules, Vol 14, Iss 3, p 334 (2024)

The human gastrointestinal system is a complex ecosystem crucial for well-being. During sepsis-induced gut injury, the integrity of the intestinal barrier can be compromised. Lipopolysaccharide (LPS), an endotoxin from Gram-negative bacteria, disrupt

Externí odkaz: https://doaj.org/article/844f655ab4b8446987bb7fecded317d7

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Akademický článek

Possible Anti-asthmatic Effect of Iraqi Ammi majus Seeds Extract Induced by Ovalbumin in Mice

Autor: Zainab T Younis, Shihab H Mutlag

Publikováno v: The Iraqi Journal of Veterinary Medicine, Vol 46, Iss 2 (2022)

Asthma is a chronic and complex condition of the respiratory tract, that occurs in both children and adults. Currently available medications have side effects; therefore, new therapies with fewer side effects are needed. Thus, present study was desig

Externí odkaz: https://doaj.org/article/3a4a7c4d875d48dd9f723b3c96a9f5b2

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Akademický článek

Evaluation of the Effect of Topical Artemisia dracunculus Administration on Serum Levels of Selected Interleukins and Spleen Index in Imiquimod-Induced Psoriasis in Male Mice Compared to Clobetasol Propionate (Dermovate (R)) Ointment

Autor: Thamer M. Mohammed, Shihab H. Mutlag, Bahaa A.Shihab

Publikováno v: Iraqi Journal of Pharmaceutical Sciences, Vol 29, Iss 2 (2020)

Psoriasis is a long-lasting autoimmune disease that is characterized by swollen skin patches. Normally, these skin patches are dark, swollen, itchy and scaly. The single application of the innate TLR7/8 ligand Imiquimod (IMQ) in mice easily induces a

Externí odkaz: https://doaj.org/article/cb31c73d31fe47a394f212a09d8f4b9b

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Akademický článek

Dose Dependent Anti-inflammatory Effect of Ammi majus Alcoholic Extract in Rat: Chronic Study

Autor: Shihab H. Mutlag

Publikováno v: Iraqi Journal of Pharmaceutical Sciences, Vol 21, Iss 1 (2017)

During treatment of inflammatory diseases, many conventional therapies (non-steroidal anti-inflammatory drugs) used to relief pain and inflammation. Chronic use of the intended drugs is frequently associated with serious side effect, which may lead t

Externí odkaz: https://doaj.org/article/320d3f1493c14e3eba93103e072a2883

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Akademický článek

The Possible Protective Effect of Simultaneous Administration of Alcoholic Ammi majus Seeds' Extract Against Gentamicininduced Nephrotoxicity in Rats

Autor: Shihab H. Muttlag, Ali A. Kasim, Ali R. Jassim

Publikováno v: Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 11, Iss 1 (2012)

In gentamicin-induced nephrotoxicity, reactive oxygen species (ROS) is believed to play a pivotal role in cellular damage and necrosis via several complex mechanisms. Ammi majus L. (Apiaceae) is a rich source of many compounds which possess, among ot

Externí odkaz: https://doaj.org/article/9b6ba337428c4c99bfb774e49e1249e7

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