Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shih-hsie Pan"'
Autor:
David S. Meyers, Li You, Zizhuo Xing, Yueming Qian, Zheng Jian Li, Paul M. Skonezny, Stankavage Robert, Jianlin Xu, Shih-Hsie Pan
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 39:1199-1208
A standard fed-batch fermentation process using 1 mM isopropyl-β-d-thiogalactopyranoside (IPTG) induction at 37 °C in complex batch and feed media had been developed for manufacturing of a therapeutic protein (TP) expressed in inclusion bodies (IBs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2139a690f2b21c0d1f2bcd16e13312b3
https://doi.org/10.1007/s10295-012-1127-8
https://doi.org/10.1007/s10295-012-1127-8
Autor:
Shih-Hsie Pan, Samiksha Nayak, Zheng Jian Li, Michael C. Borys, Susan Egan, Yueming Qian, Ying Jing
Publikováno v:
Process Biochemistry. 47:69-75
The presence of aggregated forms of proteins can be problematic for therapeutics due to the potential for immunogenic and pharmacokinetic issues. Although downstream processing can remove the aggregated forms, inhibiting aggregate formation upstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3992cbae02a8c535c671c2ed3df08141
https://doi.org/10.1016/j.procbio.2011.10.009
https://doi.org/10.1016/j.procbio.2011.10.009
Publikováno v:
Process Biochemistry. 46:1423-1429
The amino acid composition of CHO cell culture media for manufacturing an antibody fusion protein (B1) was optimized using data obtained through metabolic flux analysis. The metabolic flux analysis was performed using the metabolic rates derived from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::617150030c9ce3096758446c32a3c621
https://doi.org/10.1016/j.procbio.2011.03.014
https://doi.org/10.1016/j.procbio.2011.03.014
Autor:
Shih-Hsie Pan, Zizhuo Xing, Chao Huang, Zheng Jian Li, Vineeta Dhar, Nan-xin Qian, Li You, Yueming Qian, Xuankuo Xu
Publikováno v:
Protein expression and purification.
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d8a60ba99693f7ee42e97c49701036
https://pubmed.ncbi.nlm.nih.gov/22982086
https://pubmed.ncbi.nlm.nih.gov/22982086
Publikováno v:
Protein expression and purification. 83(1)
Recently lactose mediated auto-induction in Escherichia coli has gained a lot of interest because higher protein titer could be achieved without the need to monitor growth and add inducer at the proper time. In this study a high level therapeutic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11da0241fcfc10d739a3f5d558196e8
https://pubmed.ncbi.nlm.nih.gov/22425658
https://pubmed.ncbi.nlm.nih.gov/22425658
Autor:
Zheng Jian Li, Shih-Hsie Pan, Ying Jing, Yueming Qian, Aiqing He, Mahmoud Ghandi, Michael C. Borys
Publikováno v:
Biotechnology progress. 28(2)
Dexamethasone (DEX) was previously shown (Jing et al., Biotechnol Bioeng. 2010;107:488-496) to play a dual role in increasing sialylation of recombinant glycoproteins produced by Chinese Hamster Ovary (CHO) cells. DEX addition increased sialic acid l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757ccb94825e891b071976416ebe5c5c
https://pubmed.ncbi.nlm.nih.gov/22140034
https://pubmed.ncbi.nlm.nih.gov/22140034
Autor:
Sarwat F. Khattak, Zheng Jian Li, Zizhuo Xing, Paul S. Kayne, Nan-xin Qian, Yueming Qian, Aiqing He, Shih-Hsie Pan
Publikováno v:
Biotechnology progress. 27(4)
This study reports the effects of varying concentrations of copper sulfate on the metabolic and gene transcriptional profile of a recombinant Chinese hamster ovary (CHO) cell line producing an immunoglobulin G (IgG)-fusion protein (B0). Addition of 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529179cc03cfad6dc361c609978e0c51
https://pubmed.ncbi.nlm.nih.gov/21595052
https://pubmed.ncbi.nlm.nih.gov/21595052
Autor:
Philip P. Vella, Joan M. Staub, Jack Armstrong, Kathleen T. Dolan, Cynthia M. Rusk, Sally Szymanski, William E. Greer, Stephen Marburg, Peter J. Kniskern, Timothy L. Schofield, Richard L. Tolman, Fredrick Hartner, Shih-hsie Pan, Robert J. Gerety, Ronald W. Ellis
Publikováno v:
Pediatrics. 85:668-675
Haemophilus influenzae type b is responsible for an estimated 15 000 to 20 000 cases of meningitis per year in the United States, mainly in children 2 months to 5 years old.1-4 The mortality rate from meningitis due to H influenzae type b infections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c987d450978e72cad63ccaff4f1eb0c
https://doi.org/10.1542/peds.85.4.668
https://doi.org/10.1542/peds.85.4.668
Autor:
Zheng Jian Li, Zizhuo Xing, Chao Huang, Bruce E. Eagan, Yueming Qian, Shih-Hsie Pan, Vineeta Dhar, Li You, Nan-xin Qian, Xuankuo Xu
Publikováno v:
Applied Microbiology and Biotechnology. 96:1381-1381
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::971d395d38a3fc44598642049298312b
https://doi.org/10.1007/s00253-012-4347-y
https://doi.org/10.1007/s00253-012-4347-y
Autor:
Torleif Utne, Sterling A. Tomellin, Ronald B. Jobson, Shih-Hsie Pan, Reinhold Donald F, James M. Stevenson, Leonard M. Weinstock
Publikováno v:
Tetrahedron Letters. 27:3845-3848
The spectral and chemical properties of potassium fluoride on activated alumina, an extensively used basic catalyst in organic synthesis, show that its unusually high reactivity relative to other fluoride-containing basic systems is due to the reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::568c5155ce895ccff7b1669d52782302
https://doi.org/10.1016/s0040-4039(00)83895-2
https://doi.org/10.1016/s0040-4039(00)83895-2