Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Shih-Wei Hsu"'
Autor:
Shu-Hua Huang, Wen-Chiu Hsiao, Hsin-I Chang, Mi-Chia Ma, Shih-Wei Hsu, Chen-Chang Lee, Hong-Jie Chen, Ching-Heng Lin, Chi-Wei Huang, Chiung-Chih Chang
Publikováno v:
BMC Medical Imaging, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Based on a longitudinal cohort design, the aim of this study was to investigate whether individual-based 18F fluorodeoxyglucose positron emission tomography (18F-FDG-PET) regional signals can predict dementia conversion in patient
Externí odkaz:
https://doaj.org/article/024701af4f824508bffbdcaa0eac96f8
Autor:
Jun-Ding Zhu, Chi-Wei Huang, Hsin-I Chang, Shih-Jen Tsai, Shu-Hua Huang, Shih-Wei Hsu, Chen-Chang Lee, Hong-Jie Chen, Chiung-Chih Chang, Albert C. Yang
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 15 (2022)
Background: In light of advancements in machine learning techniques, many studies have implemented machine learning approaches combined with data measures to predict and classify Alzheimer’s disease. Studies that predicted cognitive status with lon
Externí odkaz:
https://doaj.org/article/b4d0c3da29c34771b7a89236d1e993c4
Autor:
Ya-Ting Chang, Shih-Wei Hsu, Shu-Hua Huang, Chi-Wei Huang, Wen-Neng Chang, Chia-Yi Lien, Jun-Jun Lee, Chen-Chang Lee, Chiung-Chih Chang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background Since both APOE and ABCA7 protein expression may independently reduce neuritic plaque burden and reorganize fibrillar amyloid burden-mediated disruption of functional connectivity in the default mode network, we aimed to investiga
Externí odkaz:
https://doaj.org/article/38b931b1717d41d6b2af9296ac94a638
Autor:
Hsin-I Chang, Yu-Tzu Chang, Chi-Wei Huang, Kuo-Lun Huang, Jung-Lung Hsu, Shih-Wei Hsu, Shih-Jen Tsai, Wen-Neng Chang, Chen-Chang Lee, Shu-Hua Huang, Chiung-Chih Chang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The cognitive manifestations of Alzheimer’s disease (AD) are related to brain network degeneration, and genetic differences may mediate network degeneration. Several AD-susceptible loci have been reported to involve amyloid or tau cascades; however
Externí odkaz:
https://doaj.org/article/4285d2ffba404a6095dd477158b5e128
Autor:
Hua-Tsen Hsiao, Mi-Chia Ma, Hsin-I Chang, Ching-Heng Lin, Shih-Wei Hsu, Shu-Hua Huang, Chen-Chang Lee, Chi-Wei Huang, Chiung-Chih Chang
Publikováno v:
Nutrients, Vol 14, Iss 24, p 5300 (2022)
Dietary pattern (DP) results in nutrition adequacy and may influence cognitive decline and cortical atrophy in Alzheimer’s disease (AD). The study explored DP in 248 patients with AD. Two neurobehavioral assessments (intervals 13.4 months) and two
Externí odkaz:
https://doaj.org/article/b604fbdfd64d4553a1559d9cb676daa0
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15340 (2022)
TRIM5α is a host anti-retroviral restriction factor that destroys human immunodeficiency virus (HIV) virions and triggers innate immune signaling. TRIM5α also mediates the autophagic degradation of target proteins via TRIMosome formation. We previo
Externí odkaz:
https://doaj.org/article/f87520e48abd47a48f31c641b2971590
Autor:
Hsin-I Chang, Shih-Wei Hsu, Zih-Kai Kao, Chen-Chang Lee, Shu-Hua Huang, Ching-Heng Lin, Mu-N Liu, Chiung-Chih Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14635 (2022)
The amyloid framework forms the central medical theory related to Alzheimer disease (AD), and the in vivo demonstration of amyloid positivity is essential for diagnosing AD. On the basis of a longitudinal cohort design, the study investigated clinica
Externí odkaz:
https://doaj.org/article/011a352e7f5e4f41ab8ebd6e6a68abb7
Autor:
Chao-Hsuan Chen, Pei-Chen Hsu, Shih-Wei Hsu, Kun-Ting Hong, Kai-Yuan Chen, Jie-Long He, Der-Yang Cho, Yun-Chi Wang, Wen-Shin Chang, Da-Tian Bau, Chia-Wen Tsai
Publikováno v:
Molecules, Vol 27, Iss 13, p 4106 (2022)
6-hydroxydopamine (6-OHDA) is used to induce oxidative damage in neuronal cells, which can serve as an experimental model of Parkinson’s disease (PD). Jujuboside A and B confer free radical scavenging effects but have never been examined for their
Externí odkaz:
https://doaj.org/article/a00882eab5b74fd2999123fcb7c6f45e
Autor:
Ya‐Ting Chang, Yung‐Che Chen, Yung‐Lung Chen, Shih‐Wei Hsu, Feng‐Yueh Yang, Chen‐Chang Lee, Po‐Yuan Hsu, Meng‐Chih Lin
Publikováno v:
Brain and Behavior, Vol 10, Iss 12, Pp n/a-n/a (2020)
Abstract Introduction Obstructive sleep apnea (OSA)‐associated hypoxemia, sleep fragmentation, and cerebral vascular dysfunction are implicated in cognitive dysfunction. Functional connectivity within default mode network (DMN) is a possible mechan
Externí odkaz:
https://doaj.org/article/9aaeb78c3c28446e9c8ea5640713bc92
Autor:
Chiung-Chih Chang, Ya-Ting Chang, Chi-Wei Huang, Shih-Jen Tsai, Shih-Wei Hsu, Shu-Hua Huang, Chen-Chang Lee, Wen-Neng Chang, Chun-Chung Lui, Chia-Yi Lien
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Alzheimer’s disease (AD) is a complex neurodegenerative disease, and genetic differences may mediate neuronal degeneration. In humans, a single-nucleotide polymorphism in the B-cell chronic lymphocytic leukemia/lymphoma-2 (Bcl-2
Externí odkaz:
https://doaj.org/article/ef0bc3dc55bc4c5fafe047a4e5d03ea6