Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Shih-Shin Liang"'
Publikováno v:
Molecules, Vol 28, Iss 12, p 4580 (2023)
Herein, we used isotopic formaldehyde and sodium cyanoborohydride via reductive amination to label two methyl groups on primary amine to arrange the standards (h2-formaldehyde-modified) and internal standards (ISs, d2-formaldehyde-modified) of trypto
Externí odkaz:
https://doaj.org/article/62647307718b41f9947937259c21e151
Autor:
Ping-Hsun Wu, Yi-Ting Lin, Yi-Wen Chiu, Gabriel Baldanzi, Jiun-Chi Huang, Shih-Shin Liang, Su-Chu Lee, Szu-Chia Chen, Ya-Ling Hsu, Mei-Chuan Kuo, Shang-Jyh Hwang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Protein-bound uremic toxins (Indoxyl sulfate [IS] and p-cresyl sulfate [PCS]) are both associated with cardiovascular (CV) and all-cause mortality in subjects with chronic kidney disease (CKD). Possible mechanisms have not been elucidated. I
Externí odkaz:
https://doaj.org/article/c0e1d65bcf264714ae4268af86f1e8d0
Autor:
Tsung-Hua Hsieh, Chia-Yi Hsu, Pei-Jing Yang, Chien-Chih Chiu, Shih-Shin Liang, Fu Ou-Yang, Jung-Yu Kan, Ming-Feng Hou, Tsu-Nai Wang, Eing-Mei Tsai
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112400- (2022)
Resistance to chemotherapy and hormonal therapy is a major clinical problem in breast cancer medicine, especially for cancer metastasis and recurrence. Di(2-ethylhexyl)phthalate (DEHP) affects drug resistance by an unknown mechanism of action. Here w
Externí odkaz:
https://doaj.org/article/00d3b1c688a74a52aca908b280671cb2
Autor:
Kumail Abbas, Aqeel Raza, Ross D. Vasquez, Marri Jmelou M. Roldan, Nemi Malhotra, Jong-Chin Huang, Olivia E. M. Buenafe, Kelvin H. -C. Chen, Shih-Shin Liang, Chung-Der Hsiao
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1342 (2022)
Ractopamine (RAC) is a synthetic phenethanolamine, β–adrenergic agonist used as a feed additive to develop leanness and increase feed conversion efficiency in different farm animals. While RAC has been authorized as a feed additive for pigs and ca
Externí odkaz:
https://doaj.org/article/87815a38b8554dea95dd6c19d54e6455
Autor:
Mahendra Jadhao, Eing-Mei Tsai, Ho-Chun Yang, Yih-Fung Chen, Shih-Shin Liang, Tsu-Nai Wang, Yen-Ni Teng, Hurng-Wern Huang, Li-Fang Wang, Chien-Chih Chiu
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 949 (2021)
The characteristics of phthalates had been thought to be similar to endocrine disruptors, which increases cancer risk. The role of phthalates in acquired drug resistance remains unclear. In this study, we investigated the effect of di-(2-ethylhexyl)
Externí odkaz:
https://doaj.org/article/930cdfcef9f2429bb22bfdebbbb113fa
Autor:
Chih-Yu Yang, Ting-Wen Chen, Wan-Lun Lu, Shih-Shin Liang, Hsien-Da Huang, Ching-Ping Tseng, Der-Cherng Tarng
Publikováno v:
Cells, Vol 10, Iss 1, p 114 (2021)
Chronic kidney disease (CKD) has long been known to cause significant digestive tract pathology. Of note, indoxyl sulfate is a gut microbe-derived uremic toxin that accumulates in CKD patients. Nevertheless, the relationship between gut microbiota, f
Externí odkaz:
https://doaj.org/article/9cd84d5f2efd4532a295d444f233a768
Autor:
Chih-Chang Hung, Fu-An Li, Shih-Shin Liang, Ling-Feng Wang, I-Ling Lin, Chien-Chih Chiu, Chiu-Hsien Lee, Jeff Yi-Fu Chen
Publikováno v:
Molecules, Vol 25, Iss 17, p 3815 (2020)
Prolonged treatment with cisplatin (CDDP) frequently develops chemoresistance. We have previously shown that p22phox, an endoplasmic reticulum (ER) membrane protein, confers CDDP resistance by blocking CDDP nuclear entry in oral squamous cell carcino
Externí odkaz:
https://doaj.org/article/f74be978d21f462b86e1e8e617f917d0
Autor:
Jia-Feng Chang, Chih-Yu Hsieh, Kuo-Cheng Lu, Yue-Wen Chen, Shih-Shin Liang, Chih-Cheng Lin, Chi-Feng Hung, Jian-Chiun Liou, Mai-Szu Wu
Publikováno v:
Toxins, Vol 12, Iss 6, p 364 (2020)
The nephrotoxicity of aristolochic acids (AAs), p-cresyl sulfate (PCS) and indoxyl sulfate (IS) were well-documented, culminating in tubulointerstitial fibrosis (TIF), advanced chronic kidney disease (CKD) and fatal urothelial cancer. Nonetheless, in
Externí odkaz:
https://doaj.org/article/7d7c7d5e40bc4e50b404ecaf42f84d33
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 11, Pp 20770-20788 (2014)
Phthalates are a class of plasticizers that have been characterized as endocrine disrupters, and are associated with genital diseases, cardiotoxicity, hepatotoxicity, and nephrotoxicity in the GeneOntology gene/protein database. In this study, we syn
Externí odkaz:
https://doaj.org/article/443d16d95f2d4d4caacbd6d6ea08d995
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 29, Iss 11, Pp 594-605 (2013)
Although morphological and anatomical studies indicate that varicose veins are characterized by venous wall weakening and subendothelial fibrosis, the exact underlying biochemical mechanism of their development remains unknown. Additionally, no quant
Externí odkaz:
https://doaj.org/article/a7ab6fb4d7dc474086b6b2cbdc3cca58