RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-κB ActivationSummary

Autor: Jerry Wong, Ricard Garcia-Carbonell, Matija Zelic, Samuel B. Ho, Brigid S. Boland, Shih-Jing Yao, Shalin A. Desai, Soumita Das, Núria Planell, Philip A. Harris, Joan Font-Burgada, Koji Taniguchi, John Bertin, Azucena Salas, Manolis Pasparakis, Pete J. Gough, Michelle Kelliher, Michael Karin, Monica Guma

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 295-312 (2020)

Background and Aims: Tumor necrosis factor (TNF) is a major pathogenic effector and a therapeutic target in inflammatory bowel disease (IBD), yet the basis for TNF-induced intestinal epithelial cell (IEC) death is unknown, because TNF does not kill n

Externí odkaz: https://doaj.org/article/4bf9bd1fe4534fd6a45b7e148464a13a

RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-κB Activation

Autor: P J Gough, Koji Taniguchi, Núria Planell, John Bertin, Soumita Das, Matija Zelic, Manolis Pasparakis, Philip A. Harris, Samuel B. Ho, Ricard Garcia-Carbonell, Shih Jing Yao, Joan Font-Burgada, Michelle A. Kelliher, Azucena Salas, Jerry Wong, Michael Karin, Monica Guma, Shalin A. Desai, Brigid S. Boland

Publikováno v: Cellular and molecular gastroenterology and hepatology, vol 9, iss 2
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 295-312 (2020)

Background and Aims: Tumor necrosis factor (TNF) is a major pathogenic effector and a therapeutic target in inflammatory bowel disease (IBD), yet the basis for TNF-induced intestinal epithelial cell (IEC) death is unknown, because TNF does not kill n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d066f3e6066a30628cb304b6fb9eaca
https://escholarship.org/uc/item/19s668h3