Zobrazeno 1 - 10
of 587
pro vyhledávání: '"Shih-Hwa Chiou"'
Autor:
Ya-Chi Yang, Yueh Chien, Aliaksandr A. Yarmishyn, Lee-Yieng Lim, Hao-Yu Tsai, Wen-Chuan Kuo, Ping-Hsing Tsai, Sheng-Hsien Yang, Shao-I Hong, Shih-Jen Chen, De-Kuang Hwang, Yi-Ping Yang, Shih-Hwa Chiou
Publikováno v:
Journal of Advanced Research, Vol 60, Iss , Pp 141-157 (2024)
Introduction: Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is related to the pathogenesis of various retinopathies including age-related macular degeneration (AMD). Oxidative stress is the major factor that induce
Externí odkaz:
https://doaj.org/article/d9aaf9dcd9f142e5bfe08fefa6711385
Autor:
Ping-Hsing Tsai, Jun-Ren Sun, Yueh Chien, Man Sheung Chan, Winnie Khor, Hsin-Chou Yang, Chih-Heng Huang, Chia-Ni Hsiung, Teh-Yang Hwa, Yi-Ying Lin, Chih-Ling Yeh, Mong-Lien Wang, Yi-Ping Yang, Yuh-Min Chen, Fu-Ting Tsai, Meng-Shiue Lee, Yun-Hsiang Cheng, Shan-Ko Tsai, Ping-Cheng Liu, Shih-Jie Chou, Shih-Hwa Chiou
Publikováno v:
Journal of Advanced Research, Vol 60, Iss , Pp 127-140 (2024)
Background: Modifications of lipid metabolism were closely associated with the manifestations and prognosis of coronavirus disease of 2019 (COVID-19). Pre-existing metabolic conditions exacerbated the severity of severe acute respiratory syndrome cor
Externí odkaz:
https://doaj.org/article/13cefee84e324f23954f2fee36ac6e4a
Autor:
Hsiao-Jung Kao, Ting-Yi Lin, Feng-Jen Hsieh, Jia-Ying Chien, Erh-Chan Yeh, Wan-Jia Lin, Yi-Hua Chen, Kai-Hsuan Ding, Yu Yang, Sheng-Chu Chi, Ping-Hsing Tsai, Chih-Chien Hsu, De-Kuang Hwang, Hsien-Yang Tsai, Mei-Ling Peng, Shi-Huang Lee, Siu-Fung Chau, Chen Yu Chen, Wai-Man Cheang, Shih-Jen Chen, Pui-Yan Kwok, Shih-Hwa Chiou, Mei-Yeh Jade Lu, Shun-Ping Huang
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-7 (2024)
Abstract Our study presents a 319-gene panel targeting inherited retinal dystrophy (IRD) genes. Through a multi-center retrospective cohort study, we validated the assay’s effectiveness and clinical utility and characterized the mutation spectrum o
Externí odkaz:
https://doaj.org/article/483be3c5b3ae4fb894f541f92bf270b0
Autor:
Vimalan Rengganaten, Chiu-Jung Huang, Mong-Lien Wang, Yueh Chien, Ping-Hsing Tsai, Yuan-Tzu Lan, Hooi Tin Ong, Shih-Hwa Chiou, Kong Bung Choo
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Cancer stem cells form a rare cell population in tumors that contributes to metastasis, recurrence and chemoresistance in cancer patients. Circular RNAs (circRNAs) are post-transcriptional regulators of gene expression that sponge
Externí odkaz:
https://doaj.org/article/c4bd4b4e554646af930b267c443a1768
Publikováno v:
Health Science Reports, Vol 6, Iss 11, Pp n/a-n/a (2023)
Abstract Introduction Poststernotomy mediastinitis (PSM) is a critical and life‐threatening complication that can arise after cardiac surgery. The aim of this study was to evaluate and compare the outcomes of negative pressure wound therapy (NPWT)
Externí odkaz:
https://doaj.org/article/cd8543b094104aa396b414bf5d47ec71
Autor:
Min‐Ren Chiang, Ya‐Hui Lin, Wei‐Jie Zhao, Hsiu‐Ching Liu, Ru‐Siou Hsu, Tsu‐Chin Chou, Tsai‐Te Lu, I‐Chi Lee, Lun‐De Liao, Shih‐Hwa Chiou, Li‐An Chu, Shang‐Hsiu Hu
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract Endogenous signals, namely nitric oxide (NO) and electrons, play a crucial role in regulating cell fate as well as the vascular and neuronal systems. Unfortunately, utilizing NO and electrical stimulation in clinical settings can be challeng
Externí odkaz:
https://doaj.org/article/90072ab15f9842f4872dd52094827b4d
Autor:
Tai-Heng Chen, Shih-Hsin Chang, Yu-Fu Wu, Ya-Ping Yen, Fang-Yu Hsu, Yen-Chung Chen, Yang Ming, Ho-Chiang Hsu, Yi-Ching Su, Sheng-Tang Wong, Jui-Hung Hung, Shih-Hwa Chiou, Yuh-Jyh Jong, Jun-An Chen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 144-160 (2023)
Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by the selective loss of spinal motor neurons (MNs) and concomitant muscle weakness. Mutation of SMN1 is known to cause SMA, and restoring SMN protein levels via antisense oli
Externí odkaz:
https://doaj.org/article/420741cfadc04cd1856eed780b37a795
Autor:
Anita Silas La’ah, Shih-Hwa Chiou
Publikováno v:
Cells, Vol 13, Iss 5, p 436 (2024)
Lung cancer remains a formidable global health challenge that necessitates inventive strategies to improve its therapeutic outcomes. The conventional treatments, including surgery, chemotherapy, and radiation, have demonstrated limitations in achievi
Externí odkaz:
https://doaj.org/article/4f00ae35fd7042498cf3e53cdc369816
Autor:
An Xu, Mo Liu, Mo-Fan Huang, Yang Zhang, Ruifeng Hu, Julian A. Gingold, Ying Liu, Dandan Zhu, Chian-Shiu Chien, Wei-Chen Wang, Zian Liao, Fei Yuan, Chih-Wei Hsu, Jian Tu, Yao Yu, Taylor Rosen, Feng Xiong, Peilin Jia, Yi-Ping Yang, Danielle A. Bazer, Ya-Wen Chen, Wenbo Li, Chad D. Huff, Jay-Jiguang Zhu, Francesca Aguilo, Shih-Hwa Chiou, Nathan C. Boles, Chien-Chen Lai, Mien-Chie Hung, Zhongming Zhao, Eric L. Van Nostrand, Ruiying Zhao, Dung-Fang Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The dysregulation of the m6A epitranscriptomic networks have been reported to contribute to the development of gliomas. Here, the authors utilize induced pluripotent stem cell-derived astrocytes with a p53 mutation and demonstrate that mutant p53 upr
Externí odkaz:
https://doaj.org/article/e94f230ab56e49dfb83c91e1ccf71c9f
Publikováno v:
Regenerative Therapy, Vol 22, Iss , Pp 50-58 (2023)
Introduction: Glaucoma is a vision-threatening disease associated with accelerated aging of trabecular meshwork (TM) which results in elevated intraocular pressure (IOP). Increased oxidative stress in TM plays an important role in cellular molecular
Externí odkaz:
https://doaj.org/article/814f12f486474c1b9c6729058134c625