Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Shih-Hsi Chu"'
Publikováno v:
Nucleosides and Nucleotides. 17:2367-2382
5-Halogeno-6-amino-2′-deoxyuridines were synthesized from 2′-deoxyuridine as potential thymidine phosphorylase (ThdPase) inhibitors. Among the compounds synthesized, 5-bromo-6-amino-2′-deoxyuridine (6) and 5-iodo-6-amino-2′-deoxyuridine (9) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e93ff98e6388cda494ee636bbb9a181a
https://doi.org/10.1080/07328319808004324
https://doi.org/10.1080/07328319808004324
Publikováno v:
Journal of Heterocyclic Chemistry. 34:909-915
A novel class of nucleosides with the C1, atom bonded to three hetero atoms was synthesized. 2′-Thia-2′,3′-dideoxycytidine was the pilot compound of this series. (±)-β-2′-Thia-1′,3′-dideoxycytidine (6) and (±)-α-2′-thia-2′,3′-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19a2d666b7ba4b0f61909c0e606a85e9
https://doi.org/10.1002/jhet.5570340330
https://doi.org/10.1002/jhet.5570340330
Autor:
John P. Bader, Sharon Yeagy-Bargo, Shih-Hsi Chu, Bai-Chuan Pan, Owen S. Weislow, Robert W. Buckheit, Douglas L. Mayers, Stephen H. Hughes, Paul L. Boyer, Valerie Fliakas-Boltz
Publikováno v:
Virology. 210:186-193
Virus isolates resistant to 1-[(2-hydroxyethoxy) methyl]-6-(phenylthio)thymine (HEPT) and a highly potent HEPT derivative, [1-benzyloxymethyl-5-ethyl-6-(α-pyridylthio)uracil] (NSC 648400, E-BPTU), were selected in cell culture. Cross-resistance eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f212453de8e5ae1d989050d76b467d03
https://doi.org/10.1006/viro.1995.1330
https://doi.org/10.1006/viro.1995.1330
Autor:
Yung-Chi Cheng, Shih-Hsi Chu, Ginger E. Dutschman, Elizabeth C. Rowe, Giovanna Piras, Bai-Chuan Pan, Zhi-Hao Chen
Publikováno v:
Journal of Heterocyclic Chemistry. 31:177-185
6-Arylthio and 6-arylselenoacyclonucleosides was synthesized and tested for the ability to inhibit replication of HIV-1. Lithiation of acyclonucleosides with LDA followed by reaction with the electrophiles phenyl disulfide, diphenyl diselenide, 2,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59bf251dac99f16c6c63e158b7f068f1
https://doi.org/10.1002/jhet.5570310130
https://doi.org/10.1002/jhet.5570310130
Publikováno v:
ChemInform. 22
5-Benzyl and 5-benzyloxybenzyl-substituted 3′-azido-2′,3′-dideoxyuridine, (8a and 8b), 3′-halogeno-2′,3′-dideoxyuridine, 9a, 9b, 10a, 10b, 11a and 11b, and 2′,3′-dideoxyuridine, 12a and 12b, of Scheme I were synthesized as potential a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88bbd593d1a687c1cfdb3aa484de95f9
https://doi.org/10.1002/chin.199111325
https://doi.org/10.1002/chin.199111325
Publikováno v:
ChemInform. 23
1'-Halogenomethyl, 1'-azidomethyl and 1'-disubstituted aminomethyl derivatives of BAU (5-benzylacyclouridine) and BBAU (5-benzyloxybenzylacyclouridine) were synthesized in the course of our studies of benzylacyclouridines. Two new and more convenient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adc142ccfbc15d6c250f1c3b1b8288a9
https://doi.org/10.1002/chin.199248280
https://doi.org/10.1002/chin.199248280
Autor:
Ginger E. Dutschman, Bai-Chuan Pan, Shih-Hsi Chu, Elizabeth C. Rowe, Giovanna Piras, Yung-Chi Cheng, Zhi-Hao Chen
Publikováno v:
ChemInform. 26
6-Arylthio and 6-arylselenoacyclonucleosides was synthesized and tested for the ability to inhibit replication of HIV-1. Lithiation of acyclonucleosides with LDA followed by reaction with the electrophiles phenyl disulfide, diphenyl diselenide, 2,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e23c38b681fdde4f725e5a11c1600ad
https://doi.org/10.1002/chin.199511279
https://doi.org/10.1002/chin.199511279
Publikováno v:
ChemInform. 28
A novel class of nucleosides with the C1, atom bonded to three hetero atoms was synthesized. 2′-Thia-2′,3′-dideoxycytidine was the pilot compound of this series. (±)-β-2′-Thia-1′,3′-dideoxycytidine (6) and (±)-α-2′-thia-2′,3′-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4c67906f632f5388101a6bec6d62f09
https://doi.org/10.1002/chin.199747252
https://doi.org/10.1002/chin.199747252
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1f974bf54905fd8deab27c310b308c1
https://doi.org/10.1002/chin.199916232
https://doi.org/10.1002/chin.199916232
Publikováno v:
Journal of Heterocyclic Chemistry. 29:683-689
1'-Halogenomethyl, 1'-azidomethyl and 1'-disubstituted aminomethyl derivatives of BAU (5-benzylacyclouridine) and BBAU (5-benzyloxybenzylacyclouridine) were synthesized in the course of our studies of benzylacyclouridines. Two new and more convenient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c08a3be37511e81a0e1ea189b5adccb1
https://doi.org/10.1002/jhet.5570290402
https://doi.org/10.1002/jhet.5570290402