Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shih-Feng You"'
Autor:
Logan Brase, Shih-Feng You, Ricardo D’Oliveira Albanus, Jorge L. Del-Aguila, Yaoyi Dai, Brenna C. Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P. Budde, Kristy Bergmann, John C. Morris, Randall J. Bateman, Richard J. Perrin, Eric McDade, Chengjie Xiong, Alison M. Goate, Martin Farlow, Dominantly Inherited Alzheimer Network (DIAN), Greg T. Sutherland, Jonathan Kipnis, Celeste M. Karch, Bruno A. Benitez, Oscar Harari
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Genetic studies of Alzheimer disease (AD) have prioritized variants in genes related to the amyloid cascade, lipid metabolism, and neuroimmune modulation. However, the cell-specific effect of variants in these genes is not fully understood.
Externí odkaz:
https://doaj.org/article/7041e0b0389849e49d987eee932c41c5
Autor:
Fabia Filipello, Claire Goldsbury, Shih Feng You, Alberto Locca, Celeste M. Karch, Laura Piccio
Publikováno v:
Neurobiology of Disease, Vol 165, Iss , Pp 105630- (2022)
Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by macrophages and microglia in the central nervous system (CNS). TREM2 has attracted a lot of interest in the past decade for its critical role in modula
Externí odkaz:
https://doaj.org/article/e244266022764600b040bf1e47ecf59f
Autor:
Fabia Filipello, Shih-Feng You, Farzaneh S. Mirfakhar, Sidhartha Mahali, Bryan Bollman, Mariana Acquarone, Olena Korvatska, Jacob A. Marsh, Anirudh Sivaraman, Rita Martinez, Claudia Cantoni, Luca De Feo, Laura Ghezzi, Miguel A. Minaya, Arun Renganathan, Anil G. Cashikar, Jun-Ichi Satoh, Wandy Beatty, Abhirami K. Iyer, Marina Cella, Wendy H. Raskind, Laura Piccio, Celeste M. Karch
Publikováno v:
Acta Neuropathologica. 145:749-772
TREM2 is an innate immune receptor expressed by microglia in the adult brain. Genetic variation in the TREM2 gene has been implicated in risk for Alzheimer’s disease and frontotemporal dementia, while homozygous TREM2 mutations cause a rare leukody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1808ffc92b74dc4bbdd42e0fae1c83a4
https://doi.org/10.1007/s00401-023-02568-y
https://doi.org/10.1007/s00401-023-02568-y
Autor:
Matthew J. Rosene, Simon Hsu, Shih Feng You, Logan Brase, Anthony Verbeck, Rita Martinez, Clare E. Wallace, Zeran Li, Ping Yan, Nina M. Dräger, Sydney M. Sattler, Abhirami K Iyer, Shannon L Macauley, David M. Holtzman, Bruno A. Benitez, Martin Kampmann, Carlos Cruchaga, Oscar Harari, John R. Cirrito, Jin-Moo Lee, Alison M. Goate, Celeste M. Karch
Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. AD is also the result of complex genetic architecture that can be leveraged to understand pathways central to diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ab76a709fc729b82f0921c920f141bf
https://doi.org/10.1101/2022.01.31.22270175
https://doi.org/10.1101/2022.01.31.22270175
Autor:
Brenna C Novotny, Kristy Bergmann, Helena C. Chui, Randall J. Bateman, Carolina Sariano-Tarraga, Eric McDade, Yaoyi Dai, Greg T. Sutherland, Celeste M. Karch, Maria Victoria Fernandez, Logan Brase, Jorge L Del-Aguila, Shih-Feng You, Oscar Harari, Peter R. Schofield, John C. Morris, Alison Goate, Taitea Dykstra, Jasmeer P. Chhatwal, Martin R. Farlow, Chengjie Xiong, John P. Budde, Jonathan Kipnis, Carlos Cruchaga, Bruno A. Benitez
BackgroundAlzheimer disease (AD) has substantial genetic, molecular, and cellular heterogeneity associated with its etiology. Much of our current understanding of the main AD molecular events associated with the amyloid hypothesis (APP, PSEN1 and PSE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3307e712e1c6876b435735c1ed72ab22
https://doi.org/10.1101/2021.11.30.21267072
https://doi.org/10.1101/2021.11.30.21267072
Autor:
Fabia Filipello, Shih‐Feng You, Rita Martinez, Olena Korvatska, Wendy H Raskind, Sidhartha Mahali, Laura Ghezzi, Beatty Wandy, Marina Cella, Laura Piccio, Celeste M. Karch
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dba322151661ce24e023d6a3922ab1ab
https://doi.org/10.1002/alz.058712
https://doi.org/10.1002/alz.058712
Autor:
Logan Brase, Bruno A. Benitez, Carlos Cruchaga, Fabia Filipello, June He, Shih-Feng You, Oscar Harari, Jorge L. Del-Aguila, Celeste M. Karch, Kathie A. Mihindukulasuriya
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8bbb34ae78a68e96b3ada8ae8f3529d
https://doi.org/10.1002/alz.043592
https://doi.org/10.1002/alz.043592
Autor:
Cameron L. Prigge, Nan Fu Liou, David S. McNeill, Lei Lei Liu, Samer Hattar, Po-Ting Yeh, Chi Chan Lee, Dao-Qi Zhang, Shih Feng You, Shih-Kuo Chen, Kylie S. Chew
Publikováno v:
Journal of Neuroscience. 36:7184-7197
Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs, with five subtypes named M1–M5) are a unique subclass of RGCs with axons that project directly to many brain nuclei involved in non-image-forming functions such as c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd834ff5254eb2c2515837a1322e714
https://doi.org/10.1523/jneurosci.3500-15.2016
https://doi.org/10.1523/jneurosci.3500-15.2016
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Shear wave elastography (SWE) has been widely adopted for clinical in vivo imaging of tissue elasticity for disease diagnosis, and this modality can be a valuable tool for in vitro mechanobiology studies but its full potential has yet to be explored.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed43bf449026e9821823a0c717adc28e
https://pubmed.ncbi.nlm.nih.gov/30262836
https://pubmed.ncbi.nlm.nih.gov/30262836
Autor:
Prigge, Cameron L., Po-Ting Yeh, Nan-Fu Liou, Chi-Chan Lee, Shih-Feng You, Lei-Lei Liu, McNeill, David S., Chew, Kylie S., Hattar, Samer, Shih-Kuo Chen, Dao-Qi Zhang
Publikováno v:
Journal of Neuroscience; 7/6/2016, Vol. 36 Issue 27, p7184-7197, 14p