Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shih Ching Chou"'
Autor:
Wilhelm, H.
Publikováno v:
Revue Bibliographique de Sinologie, 1961 Jan 01. 7, 288-289.
Externí odkaz:
https://www.jstor.org/stable/24607681
Autor:
Tae-In Kam, Hyejin Park, Shih-Ching Chou, Jonathan G. Van Vranken, Melanie J. Mittenbühler, Hyeonwoo Kim, Mu A, Yu Ree Choi, Devanik Biswas, Justin Wang, Yu Shin, Alexis Loder, Senthilkumar S. Karuppagounder, Christiane D. Wrann, Valina L. Dawson, Bruce M. Spiegelman, Ted M. Dawson
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Physical activity provides clinical benefit in Parkinson’s disease (PD). Irisin is an exercise-induced polypeptide secreted by skeletal muscle that crosses the blood–brain barrier and mediates certain effects of exercise. Here, we show that irisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674159bdf1058fe33e3f716e89d94867
https://doi.org/10.1073/pnas.2204835119
https://doi.org/10.1073/pnas.2204835119
Publikováno v:
Faculty Reviews
The worldwide health-care burden of neurodegenerative diseases is on the rise—a crisis created through a combination of increased caseload and lack of effective treatments. The limitations of pharmacotherapy in these disorders have led to an urgent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bbc63769e3c50074b6be0c10af2431
https://doi.org/10.12703/r/10-81
https://doi.org/10.12703/r/10-81
Autor:
Nikhil Panicker, Tae-In Kam, Hu Wang, Stewart Neifert, Shih-Ching Chou, Manoj Kumar, Saurav Brahmachari, Aanishaa Jhaldiyal, Jared T. Hinkle, Fatih Akkentli, Xiaobo Mao, Enquan Xu, Senthilkumar S. Karuppagounder, Eric T. Hsu, Sung-Ung Kang, Olga Pletnikova, Juan Troncoso, Valina L. Dawson, Ted M. Dawson
Publikováno v:
Neuron. 110(15)
Parkinson's disease (PD) is mediated, in part, by intraneuronal accumulation of α-synuclein aggregates andsubsequent death of dopamine (DA) neurons in the substantia nigra pars compacta (SNpc). Microglial hyperactivation of the NOD-like receptor pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71ad779e7f6589ab8ba8fc4d9514428
https://pubmed.ncbi.nlm.nih.gov/35926449
https://pubmed.ncbi.nlm.nih.gov/35926449
Autor:
Hyejin Park, Tae-In Kam, Hanjing Peng, Shih-Ching Chou, Amir A. Mehrabani-Tabari, Jae-Jin Song, Xiling Yin, Senthilkumar S. Karuppagounder, George K. Umanah, A.V. Subba Rao, YuRee Choi, Akanksha Aggarwal, Sohyun Chang, Hyunhee Kim, Jiyoung Byun, Jun O. Liu, Ted M. Dawson, Valina L. Dawson
Publikováno v:
Cell. 185:1943-1959.e21
Parthanatos-associated apoptosis-inducing factor (AIF) nuclease (PAAN), also known as macrophage migration inhibitor factor (MIF), is a member of the PD-D/E(X)K nucleases that acts as a final executioner in parthanatos. PAAN's role in Parkinson's dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0feb3b87be13d623a52c38e1171fab4
https://doi.org/10.1016/j.cell.2022.04.020
https://doi.org/10.1016/j.cell.2022.04.020
Autor:
Jacob K. Sterling, Tae-In Kam, Samyuktha Guttha, Hyejin Park, Bailey Baumann, Amir A. Mehrabani-Tabari, Hannah Schultz, Brandon Anderson, Ahab Alnemri, Shih-Ching Chou, Juan C. Troncoso, Valina L. Dawson, Ted M. Dawson, Joshua L. Dunaief
Publikováno v:
Cell Reports. 38:110358
α-synuclein (α-syn) aggregation and accumulation drive neurodegeneration in Parkinson's disease (PD). The substantia nigra of patients with PD contains excess iron, yet the underlying mechanism accounting for this iron accumulation is unclear. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ec1dbfc491f73f25bcdcdbb2e1bc2d
https://doi.org/10.1016/j.celrep.2022.110358
https://doi.org/10.1016/j.celrep.2022.110358
Autor:
Tae In Kam, Areum Jo, Sungtaek Oh, Yunjong Lee, Sung Ung Kang, Shaida A. Andrabi, Byoung Dae Lee, Ho Chul Kang, Haisong Jiang, Hojin Kang, Lino Tessarollo, Chan Hyun Na, Yun Il Lee, Senthilkumar S. Karuppagounder, Deborah A. Swing, Manoj Kumar, George K.E. Umanah, Xiaobo Mao, Chi Hu Park, Ted M. Dawson, Jin Whan Cho, Hyo Jung Kim, Sangwoo Ham, Han Seok Ko, Hyein Kim, Ji-Yeong Lee, Sheila K. Pirooznia, Joo Ho Shin, Valina L. Dawson, Shih Ching Chou, Hanna Kim, Sun Ha Paek, Stewart Neifert, Hyejin Park, Rin Khang
Publikováno v:
Sci Transl Med
Accumulation of the parkin-interacting substrate (PARIS; ZNF746), due to inactivation of parkin, contributes to Parkinson's disease (PD) through repression of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α; PPARGC1A) activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d3710904569e53b6b64fb0dbbabb29
https://pubmed.ncbi.nlm.nih.gov/34321320
https://pubmed.ncbi.nlm.nih.gov/34321320
Autor:
Hyejin Park, Rong Chen, Nikhil Panicker, Han Seok Ko, Valina L. Dawson, Shaida A. Andrabi, Xiaobo Mao, Tae In Kam, Ted M. Dawson, Alexander Pantelyat, Shih Ching Chou, Senthilkumar S. Karuppagounder, Liana S. Rosenthal, Saurav Brahmachari, Guy G. Poirier, Juan C. Troncoso, George Essien Umanah, Lynn M. Bekris, Chen Qi, Seung Pil Yun, James B. Leverenz, Olga Pletnikova
Publikováno v:
Science. 362
PAR promotes α-synuclein toxicity How pathologic α-synuclein (α-syn) leads to neurodegeneration in Parkinson's disease (PD) remains poorly understood. Kam et al. studied the α-syn preformed fibril (α-syn PFF) model of sporadic PD (see the Perspe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd532fdb1d3ad3b98bdb6879d1df55f
https://doi.org/10.1126/science.aat8407
https://doi.org/10.1126/science.aat8407
Autor:
Shih Chieh Yen, Shih Ching Chou, Fu Yuan Tsai, Ming Hua Hsu, Hong Chuang, Yu-Chuan Liang, Tsurng Juhn Huang, Jia-Cherng Horng, Chia Wen Chen, Yu Cheng Kuo, Hui Hsien Lin
Publikováno v:
European Journal of Medicinal Chemistry. 90:428-435
Hepatitis B virus (HBV) is a causative reagent that frequently causes progressive liver diseases, leading to the development of acute, chronic hepatitis, cirrhosis, and eventually hepatocellular carcinoma (HCC). Despite several antiviral drugs includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34eab698bdf397e4ef3b9e1ae4a5d5eb
https://doi.org/10.1016/j.ejmech.2014.11.050
https://doi.org/10.1016/j.ejmech.2014.11.050
Autor:
Hong Chuang, Chia-Ching Chang, Hui Hsien Lin, Jih Ru Hwu, Yu-Chuan Liang, Cheng Ying Hsieh, Lin Chiang Sherlock Huang, Shih Ching Chou, Yi Wei Chen, Mohit Kapoor, Ming Hua Hsu
Publikováno v:
RSC Advances. 5:107833-107838
In this research, we designed and synthesized a new series of nordihydroguaiaretic acid (NDGA) derivatives for multidrug resistance (MDR) research. A methylsulfonyl NDGA derivative, ((2R,3S)-2,3-dimethylbutane-1,4-diyl)bis(benzene-4,1,2-triyl) tetram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c43c841cf1c7b8ccc6789f4deaf75423
https://doi.org/10.1039/c5ra18827j
https://doi.org/10.1039/c5ra18827j