Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Shih‐Jen Chen"'
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 12, Pp 3149-3159 (2024)
Abstract Introduction This study aimed to investigate the impact of aflibercept and dexamethasone (DEX) on the formation of epiretinal membrane (ERM) and their treatment outcomes in eyes with diabetic macular edema (DME). Methods In this retrospectiv
Externí odkaz:
https://doaj.org/article/cf12b7a94a4241a2a1c021e72ab1c444
Autor:
Ya-Chi Yang, Yueh Chien, Aliaksandr A. Yarmishyn, Lee-Yieng Lim, Hao-Yu Tsai, Wen-Chuan Kuo, Ping-Hsing Tsai, Sheng-Hsien Yang, Shao-I Hong, Shih-Jen Chen, De-Kuang Hwang, Yi-Ping Yang, Shih-Hwa Chiou
Publikováno v:
Journal of Advanced Research, Vol 60, Iss , Pp 141-157 (2024)
Introduction: Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is related to the pathogenesis of various retinopathies including age-related macular degeneration (AMD). Oxidative stress is the major factor that induce
Externí odkaz:
https://doaj.org/article/d9aaf9dcd9f142e5bfe08fefa6711385
Autor:
Shih‐Jie Chou, Yi‐Ping Yang, Min‐Ren Chiang, Chih‐Ying Chen, Henkie Isahwan Ahmad Mulyadi Lai, Yi‐Ying Lin, You‐Ren Wu, I‐Chieh Wang, Aliaksandr A. Yarmishyn, Guang‐Yuh Chiou, Tai‐Chi Lin, De‐Kuang Hwang, Shih‐Jen Chen, Yueh Chien, Shang‐Hsiu Hu, Shih‐Hwa Chiou
Publikováno v:
Small Science, Vol 4, Iss 8, Pp n/a-n/a (2024)
Eye fundus diseases, such as retinal degenerative diseases, which lead to blindness in ≈12% of individuals aged >65 years, cause permanent damage to retinal cells. The antioxidant quercetin (QC) is promising for the effective treatment of eye fundu
Externí odkaz:
https://doaj.org/article/05be5d5726224b24893f31a9b79382e9
Autor:
Kelvin Yi Chong Teo, Kyu-Hyung Park, Nor Fariza Ngah, Shih-Jen Chen, Paisan Ruamviboonsuk, Ryusaburo Mori, Nagako Kondo, Won Ki Lee, Rajesh Rajagopalan, Ryo Obata, Ian Y. H. Wong, Caroline Chee, Hiroko Terasaki, Tetsuju Sekiryu, Shih-Chou Chen, Yasuo Yanagi, Shigeru Honda, Timothy Y. Y. Lai, Chui Ming Gemmy Cheung
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 4, Pp 935-954 (2024)
Abstract Introduction The EVEREST II study previously reported that intravitreally administered ranibizumab (IVR) combined with photodynamic therapy (PDT) achieved superior visual gain and polypoidal lesion closure compared to IVR alone in patients w
Externí odkaz:
https://doaj.org/article/7c0da20fff674871a1afe773e1ed28b1
Autor:
Hsiao-Jung Kao, Ting-Yi Lin, Feng-Jen Hsieh, Jia-Ying Chien, Erh-Chan Yeh, Wan-Jia Lin, Yi-Hua Chen, Kai-Hsuan Ding, Yu Yang, Sheng-Chu Chi, Ping-Hsing Tsai, Chih-Chien Hsu, De-Kuang Hwang, Hsien-Yang Tsai, Mei-Ling Peng, Shi-Huang Lee, Siu-Fung Chau, Chen Yu Chen, Wai-Man Cheang, Shih-Jen Chen, Pui-Yan Kwok, Shih-Hwa Chiou, Mei-Yeh Jade Lu, Shun-Ping Huang
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-7 (2024)
Abstract Our study presents a 319-gene panel targeting inherited retinal dystrophy (IRD) genes. Through a multi-center retrospective cohort study, we validated the assay’s effectiveness and clinical utility and characterized the mutation spectrum o
Externí odkaz:
https://doaj.org/article/483be3c5b3ae4fb894f541f92bf270b0
Autor:
Chang-Chi Weng, Sheng-Chu Chi, Tai-Chi Lin, Yi-Ming Huang, Yu-Bai Chou, De-Kuang Hwang, Shih-Jen Chen
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301096 (2024)
This retrospective study aimed to determine the short-term efficacy and safety of brolucizumab treatment for recalcitrant neovascular age-related macular degeneration (nAMD) in a real-world setting in Taiwan. Recalcitrant nAMD patients who were treat
Externí odkaz:
https://doaj.org/article/9436a7a1a1ec48d2a35403d64cb70383
Publikováno v:
Taiwan Journal of Ophthalmology, Vol 13, Iss 4, Pp 548-551 (2023)
Sympathetic ophthalmia (SO) is a bilateral granulomatous panuveitis. We report a rare case of SO presenting after scleral necrosis as a late complication of Gamma Knife radiotherapy for choroidal melanoma. A 55-year-old woman presented with primary c
Externí odkaz:
https://doaj.org/article/9fb8c4df0fdf4517be19e59a4fba6ba7
Autor:
Yueh Chien, Yu-Jer Hsiao, Shih-Jie Chou, Ting-Yi Lin, Aliaksandr A. Yarmishyn, Wei-Yi Lai, Meng-Shiue Lee, Yi-Ying Lin, Tzu-Wei Lin, De-Kuang Hwang, Tai-Chi Lin, Shih-Hwa Chiou, Shih-Jen Chen, Yi-Ping Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-27 (2022)
Abstract Inherited Retinal Diseases (IRDs) are considered one of the leading causes of blindness worldwide. However, the majority of them still lack a safe and effective treatment due to their complexity and genetic heterogeneity. Recently, gene ther
Externí odkaz:
https://doaj.org/article/887fadca68d047b4aadd5c83a6bb202c
Autor:
Tsai-Chu Yeh, An-Chun Luo, Yu-Shan Deng, Yu-Hsien Lee, Shih-Jen Chen, Po-Han Chang, Chun-Ju Lin, Ming-Chi Tai, Yu-Bai Chou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract While prognosis and risk of progression are crucial in developing precise therapeutic strategy in neovascular age-related macular degeneration (nAMD), limited predictive tools are available. We proposed a novel deep convolutional neural netw
Externí odkaz:
https://doaj.org/article/1a0930c56bc74f1d894963076971f103
Autor:
Cheng-Kuo Cheng, Shih-Jen Chen, Jiann-Torng Chen, Lee-Jen Chen, San-Ni Chen, Wen-Lu Chen, Sheng-Min Hsu, Chien-Hsiung Lai, Shwu-Jiuan Sheu, Pei-Chang Wu, Wei-Chi Wu, Wen-Chuan Wu, Chung-May Yang, Ling Yeung, Ta-Ching Chen, Chang-Hao Yang
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract The management of neovascular age-related macular degeneration (nAMD) has taken a major stride forward with the advent of anti-VEGF agents. The treat-and-extend (T&E) approach is a refined management strategy, tailoring to the individual pat
Externí odkaz:
https://doaj.org/article/c26ef5643bfb438e97f3c578fbbd923b