Morphologic and Molecular Heterogeneity of High-grade Serous Carcinoma Precursor Lesions.

Autor: Chien YW; Departments of Gynecology and Obstetrics.; Department of Oncology, Division of Quantitative Science, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine., Wang Y; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Huang P; Department of Oncology, Division of Quantitative Science, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Lawson BC; Department of Pathology, MD Anderson Cancer Center, Houston, TX., Kolin DL; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Chui MH; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Vang R; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Numan TA; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Soong TR; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA., Wang BG; Department of Pathology, Inova Fairfax Hospital.; University of Virginia School of Medicine Inova Campus, Falls Church, VA.; Department of Pathology, Georgetown University Medical Center, Washington, DC., Smith SA; Legacy Health Systems, Portland, OR., Chen CL; Department of Pathology, Taipei Medical University, Taipei, Taiwan., Stone R; Departments of Gynecology and Obstetrics., Douville C; Department of Oncology, Division of Quantitative Science, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine., Wang TL; Departments of Gynecology and Obstetrics.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Shih IM; Departments of Gynecology and Obstetrics.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

Publikováno v: The American journal of surgical pathology [Am J Surg Pathol] 2024 Apr 01; Vol. 48 (4), pp. 475-486. Date of Electronic Publication: 2024 Feb 01.

Association of glutaminase expression with immune-suppressive tumor microenvironment, clinicopathologic features, and clinical outcomes in endometrial cancer.

Autor: Asaka S; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.; Department of Laboratory Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan., Verma N; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Yen TT; Department of Gynecology and Obstetrics, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Hicks JL; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Nonogaki H; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Shen YA; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, Taipei Medical University, Taipei, Taiwan., Hong J; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Asaka R; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan., DeMarzo AM; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Wang TL; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.; Department of Gynecology and Obstetrics, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Shih IM; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.; Department of Gynecology and Obstetrics, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Gaillard S; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA stephanie.gaillard@jhmi.edu.; Department of Gynecology and Obstetrics, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Publikováno v: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2024 Nov 04; Vol. 34 (11), pp. 1737-1744. Date of Electronic Publication: 2024 Nov 04.

Combined assembloid modeling and 3D whole-organ mapping captures the microanatomy and function of the human fallopian tube.

Autor: Crawford AJ; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA., Forjaz A; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA., Bons J; Buck Institute for Research on Aging, Novato, CA 94945, USA., Bhorkar I; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA., Roy T; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA., Schell D; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA., Queiroga V; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA., Ren K; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA., Kramer D; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Biotechnology, Johns Hopkins Advanced Academic Programs, The Johns Hopkins University, Baltimore, MD 21218, USA., Huang W; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Biology, The Johns Hopkins University, Baltimore, MD 21218, USA., Russo GC; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA., Lee MH; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA., Wu PH; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA., Shih IM; Department of Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Wang TL; Department of Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Atkinson MA; Departments of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida Diabetes Institute, Gainesville, FL 32610, USA.; Departments of Pediatrics, College of Medicine, University of Florida Diabetes Institute, Gainesville, FL 32610, USA., Schilling B; Buck Institute for Research on Aging, Novato, CA 94945, USA., Kiemen AL; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Functional Anatomy and Evolution, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Wirtz D; Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Publikováno v: Science advances [Sci Adv] 2024 Sep 27; Vol. 10 (39), pp. eadp6285. Date of Electronic Publication: 2024 Sep 27.

Single-molecule epiallelic profiling of DNA derived from routinely collected Pap specimens for noninvasive detection of ovarian cancer.

Autor: O'Keefe CM; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA., Zhao Y; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA., Cope LM; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Departments of Oncology and Biostatistics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Ho CM; Gynecologic Cancer Center, Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan.; School of Medicine, Fu Jen Catholic University, New Taipei, Taiwan., Fader AN; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Stone R; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Ferris JS; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Beavis A; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Levinson K; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Greater Baltimore Medical Center, Towson, Maryland, USA., Wethington S; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Wang TL; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Pisanic TR; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, Maryland, USA., Shih IM; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Wang TH; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.

Publikováno v: Clinical and translational medicine [Clin Transl Med] 2024 Aug; Vol. 14 (8), pp. e1778.

Salpingectomy for ectopic pregnancy reduces ovarian cancer risk-a nationwide study.

Autor: Yen JC; Department of Ophthalmology, Taipei Ren-Ai Branch, and Department of Education and Research, Taipei City Hospital, Taipei, Taiwan.; Graduate Institute of Biomedical Informatics, Taipei Medical University, Taipei, Taiwan., Wu TI; Department of Obstetrics and Gynecology, Wan Fang Hospital, Taipei Medical University, Cancer Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Stone R; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Wang TL; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, MD, USA., Visvanathan K; Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, MD, USA., Chen LY; Graduate Institute of Data Science, Taipei Medical University, Taipei, Taiwan., Hsu MH; Graduate Institute of Data Science, Taipei Medical University, Taipei, Taiwan., Shih IM; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Publikováno v: JNCI cancer spectrum [JNCI Cancer Spectr] 2024 Apr 30; Vol. 8 (3).