Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Shigeyuki Takeyama"'
Publikováno v:
Biological and Pharmaceutical Bulletin. 21:339-345
We investigated the antitumor effect of vitamin A(VA) using the double grafted tumor technique to examine whether VA administered into a primary tumor (intralesionally or i.l.) accelerates antitumor immune reactions so that growth of the secondary tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51837f52fb771c8aa207179e66d43a7
https://doi.org/10.1248/bpb.21.339
https://doi.org/10.1248/bpb.21.339
Publikováno v:
International Journal of Immunopharmacology. 18:311-319
Inhibitory effects on some immunological responses and MethA fibrosarcoma growth in the double grafted tumor system in mice were compared between 6-mercaptopurine (6-MP) and its novel water-soluble derivative, γ-(9H-purine-6-yl)thiomethyl l -glutama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48844b2c8a4a4f986999c378c1fe55bd
https://doi.org/10.1016/0192-0561(96)00026-4
https://doi.org/10.1016/0192-0561(96)00026-4
Publikováno v:
Biologicalpharmaceutical bulletin. 21(1)
Effects of the administration of γ-(9H-purine-6-yl)thiomethyl L-glutamate (6-MPG), a water-soluble derivative of 6-mercaptopurine, on concomitant and sinecomitant immunity against the implanted MethA tumor were studied in BALB/C mice. In the concomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98035b94231a87c4b674d052be583c6
https://pubmed.ncbi.nlm.nih.gov/9477163
https://pubmed.ncbi.nlm.nih.gov/9477163
Autor:
Atsuko Sakai, Kazuaki Naito, Tatsuo Kashida, Shigeyuki Takeyama, Kei Tsuzurahara, Kenji Tsujihara, Naoko Narasaki
Publikováno v:
Immunopharmacology. 37(1)
We investigated possible mechanisms of the antitumor action of γ -(9H-purine-6-yl) thiomethyl l -glutamate (6-MPG), a water-soluble derivative of 6-MP. In the double grafted tumor system, BALB/c mice were inoculated intradermally with 10 6 cells of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca345b470f1b236a7bfc5c9a0c26b78
https://pubmed.ncbi.nlm.nih.gov/9285248
https://pubmed.ncbi.nlm.nih.gov/9285248
Autor:
Naoko Narasaki, Shigeyuki Takeyama, Kenji Tsujihara, Tatsuo Kashida, Kei Tsuzurahara, Atsuko Sakai
Publikováno v:
Biologicalpharmaceutical bulletin. 18(11)
We investigated the antitumor effect of 6-mercaptopurine (6-MP) and its analogs using the double grafted tumor technique. BALB/c mice were inoculated intradermally with MethA fibrosarcoma cells at the right inguinal region on day 0 (the primary tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fefc94fe0b34bd572444f2738ff3af8
https://pubmed.ncbi.nlm.nih.gov/8593465
https://pubmed.ncbi.nlm.nih.gov/8593465
Autor:
Kazuhiko Kondo, Masayoshi Yoshikawa, Susumu Chishima, Yuji Miura, Kohkichi Hayashida, Shigeyuki Takeyama
Publikováno v:
Drug Metabolism and Pharmacokinetics. 4:515-528
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b61941b6884d18b8f55b6e83a8e9748c
https://doi.org/10.2133/dmpk.4.515
https://doi.org/10.2133/dmpk.4.515
Publikováno v:
Japanese Journal of Pharmacology. 34:417-427
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a1ba63ee730080f0b2a21fa026dc7cb
https://doi.org/10.1016/s0021-5198(19)52296-x
https://doi.org/10.1016/s0021-5198(19)52296-x
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 25:1061-1072
Synthesis of 2-dimethylamino–2–phenylbutanol 3,4,5-trimethoxybenzoate (Trimebutine, I) labeled with carbon-14 and deuterium, and of its alcohol- and acid–moiety metabolites labeled with deuterium are described. Carbon–14–labeled I was obtai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dfe6f822cdf8d836c15f92fc597665f
https://doi.org/10.1002/jlcr.2580251003
https://doi.org/10.1002/jlcr.2580251003
Autor:
Kohki Takashima, Tamon Moriya, Sadao Maeda, Shigeyuki Takeyama, Tetsuji Mori, Seiichi Takabe, Kazuo Matsumoto
Publikováno v:
Journal of Medicinal Chemistry. 29:333-341
A series of 2,5-disubstituted 4-oxazoleacetic acid derivatives was synthesized and evaluated for hypolipidemic activity. Among them, those with a thienyl group at C-5 of the oxazole ring exerted highly potent hypolipidemic effects in rats. 2-(4-Fluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8a426ca62f015fa8249c7b6de259841
https://doi.org/10.1021/jm00153a006
https://doi.org/10.1021/jm00153a006
Publikováno v:
Japanese Journal of Pharmacology. 40:37-46
Effects of TA-5707F [6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide] and its sodium salt (TA-5707) on IgE-induced homologous PCA in rats were investigated. 1. Both TA-5707 and TA-5707F were found to be orally effective inhibitors of rat PCA. Max
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629d027deb4c430d5d30688465c79615
https://doi.org/10.1254/jjp.40.37
https://doi.org/10.1254/jjp.40.37