Výsledky vyhledávání - "Shigeyuki Imamura"

Akademický článek

A Review of Cyclic Phosphatidic Acid and Other Potential Therapeutic Targets for Treating Osteoarthritis

Autor: Tamotsu Tsukahara, Shigeyuki Imamura, Toshiro Morohoshi

Publikováno v: Biomedicines, Vol 11, Iss 10, p 2790 (2023)

Osteoarthritis (OA), a chronic degenerative joint disease, is the most common form of arthritis. OA occurs when the protective cartilage that cushions the ends of bones gradually breaks down. This leads to the rubbing of bones against each other, res

Externí odkaz: https://doaj.org/article/662dc669fe0e48c5b6cd329c93c64908

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Effects of 2-carba-cyclic phosphatidic acid derivatives on IL-1β-stimulated human chondrocytes

Autor: Masaki Yoshii, Shigeyuki Imamura, Toshiro Morohoshi, Tamotsu Tsukahara

Publikováno v: Prostaglandinsother lipid mediators. 164

Osteoarthritis (OA) is a common joint disease characterized by the breakdown of subchondral bone and cartilage damage, most often affecting middle-aged and elderly people. Although the etiology of OA is still unknown, some reports suggest that inflam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b314e29ff2a8572bffa02953b166468
https://pubmed.ncbi.nlm.nih.gov/36513319

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The majority of lipoprotein lipase in plasma is bound to remnant lipoproteins: A new definition of remnant lipoproteins

Autor: Koichi Sato, Shigeyuki Imamura, Tetsuo Machida, Junji Kobayashi, Peter J. Havel, Masami Murakami, Hiroyuki Sumino, Katsuyuki Nakajima, Kazuya Miyashita, Ernst J. Schaefer, Kimber L. Stanhope, Fumikazu Okajima

Publikováno v: Sato, Koichi; Okajima, Fumikazu; Miyashita, Kazuya; Imamura, Shigeyuki; Kobayashi, Junji; Stanhope, Kimber L; et al.(2016). The majority of lipoprotein lipase in plasma is bound to remnant lipoproteins: A new definition of remnant lipoproteins.. Clinica chimica acta; international journal of clinical chemistry, 461, 114-125. doi: 10.1016/j.cca.2016.06.020. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/1ts8645d

Background Lipoprotein lipase (LPL) is a multifunctional protein and a key enzyme involved in the regulation of lipoprotein metabolism. We determined the lipoproteins to which LPL is bound in the pre-heparin and post-heparin plasma. Methods Tetrahydr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856151f17923afbcc21b4359cbd5f047
https://doi.org/10.1016/j.cca.2016.06.020

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Plasma Activity of Endothelial Lipase Impacts High-Density Lipoprotein Metabolism and Coronary Risk Factors in Humans

Autor: Tomoyuki Yasuda, Noriaki Kinoshita, Katsuyuki Nakajima, Li Sun, Tatsuro Ishida, Shigeyuki Imamura, Kazuya Miyashita, Ken-ichi Hirata, Ryuji Toh, Kenta Mori

Publikováno v: Journal of Atherosclerosis and Thrombosis. 21:313-321

Aim Endothelial lipase (EL) is a determinant of plasma levels of high-density lipoprotein cholesterol (HDL-C). However, little is known about the impact of EL activity on plasma lipid profile. We aimed to establish a new method to evaluate EL-specifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64ba758678f6f806f3fb4f2f746ca04
https://doi.org/10.5551/jat.20131

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A new enzyme-linked immunosorbent assay system for human hepatic triglyceride lipase

Autor: Makoto Nara, Junji Kobayashi, Peter J. Havel, Tetsuo Machida, Kazuya Miyashita, Katsuyuki Nakajima, Kimber L. Stanhope, Masami Murakami, Shigeyuki Imamura, Hiroyuki Sumino, Noriaki Kinoshita

Publikováno v: Miyashita, Kazuya; Kobayashi, Junji; Imamura, Shigeyuki; Kinoshita, Noriaki; Stanhope, Kimber L; Havel, Peter J; et al.(2013). A new enzyme-linked immunosorbent assay system for human hepatic triglyceride lipase.. Clinica chimica acta; international journal of clinical chemistry, 424, 201-206. doi: 10.1016/j.cca.2013.06.016. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/65x7k4cc

BACKGROUND: The objective of this study was to establish a new sandwich based enzyme linked immunosorbent assay (ELISA) for measuring the protein mass of human hepatic triacylglyceride lipase (HTGL). METHOD: Two mouse monoclonal antibodies raised aga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17662defe82796173434052c116a66fd
https://doi.org/10.1016/j.cca.2013.06.016

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Association of angiopoietin-like protein 3 with hepatic triglyceride lipase and lipoprotein lipase activities in human plasma

Autor: Junji Kobayashi, E. F. Schaefer, Takeaki Nagamine, Seiko Otokozawa, Takamitsu Nakano, Hiroshi Mabuchi, Katsuyuki Nakajima, Masumi Ai, Shigeyuki Imamura, Yoshiharu Tokita

Publikováno v: Annals of Clinical Biochemistry. 47(5):423-431

金沢大学医学系研究科
Background: The relationship between plasma angiopoietin-like protein 3 (ANGPTL3), and lipoprotein lipase (LPL) activity and hepatic triglyceride lipase (HTGL) activity has not been investigated in the metabolism o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc288d9132e0c1bf71afe5612775c186
http://hdl.handle.net/2297/25429

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A novel colorimetric assay for the determination of lysophosphatidic acid in plasma using an enzymatic cycling method

Autor: Tatsuya Kishimoto, Koji Mizuno, Shigeyuki Imamura, Takeshi Matsuoka

Publikováno v: Clinica Chimica Acta. 333:59-67

Background : Several methods for measuring concentrations of lysophosphatidic acid (LPA), a lipid mediator, have been reported to date. However, these methods are not routinely used because most of them require specialized instrument and a complicate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83eaec5fe38a54ebb4e94aa5afef418d
https://doi.org/10.1016/s0009-8981(03)00165-7

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A highly sensitive chemiluminescent reverse transcriptase assay for human immunodeficiency virus

Autor: Youko Nagai-Fujii, Hideo Misaki, Kenji Arai, Kouichi Sano, Fumitomo Odawara, Hiroshi Azuma, Takehiro Kohno, Hideki Abe, Sharad Mohan, Kenji Ikebuchi, Shigeyuki Imamura, Hisami Ikeda

Publikováno v: Journal of Virological Methods. 106:115-124

A simple and highly sensitive reverse transcriptase (RT) assay was developed by combining a previously reported non-radioisotopic RT assay with the use of a template-primer-immobilized microplate, an enzyme capture protocol, product digestion and a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef098bcb1dc84bf098900a5533b21097
https://doi.org/10.1016/s0166-0934(02)00142-8

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A Novel Prokaryotic Phospholipase A2

Autor: Shigeyuki Imamura, Masanori Sugiyama, Hideo Misaki, Tohru Koike, Miho Izuhara, Kazuhiro Ohtani, Koji Suzuki

Publikováno v: Journal of Biological Chemistry. 277:20051-20058

Until now, phospholipase A2(PLA2; EC 3.1.14) has been found only from eukaryotic sources. In the present study, we found a secreted PLA2, which is produced by a soil bacterium, Streptomyces violaceoruber A-2688, demonstrating that the enzyme is the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1086c55f0af1c31aae652ec4ff499b53
https://doi.org/10.1074/jbc.m200264200

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Streptomyces Phospholipase A2: Its Use in the Enzymatic Measurement of Calcium(II) Ion Content

Autor: Yasuyuki Matoba, Tohru Koike, Takanori Kumagai, Masanori Sugiyama, Shigeyuki Imamura

Publikováno v: Actinomycetologica. 16:17-20

A secreted phospholipase A2 (PLA2) has been discovered. It is produced by Streptomyces violaceoruber A-2688 and is the first PLA2 identified in prokaryote. In this study, the enzyme is demonstrated to be useful in measuring the content of calcium(II)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8261c1c6e202a8ce47302bc84257d9a5
https://doi.org/10.3209/saj.16_17

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