Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Shigeyoshi Matsumura"'
Autor:
Mst. Ayesha Siddika, Hiroki Oi, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Shigeyoshi Matsumura, Yoshiya Ikawa
Publikováno v:
Molecules, Vol 28, Iss 18, p 6465 (2023)
The multimolecular assembly of three-dimensionally structured proteins forms their quaternary structures, some of which have high geometric symmetry. The size and complexity of protein quaternary structures often increase in a hierarchical manner, wi
Externí odkaz:
https://doaj.org/article/2d7fb47b4f684e859bc0456c42aebf42
Autor:
Tomoki Ueda, Kei-ichiro Nishimura, Yuka Nishiyama, Yuto Tominaga, Katsushi Miyazaki, Hiroyuki Furuta, Shigeyoshi Matsumura, Yoshiya Ikawa
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 654 (2023)
Alternative splicing is an important mechanism in the process of eukaryotic nuclear mRNA precursors producing multiple protein products from a single gene. Although group I self-splicing introns usually perform regular splicing, limited examples of a
Externí odkaz:
https://doaj.org/article/383f906272d94d939174644bdd4afc7d
Autor:
Mst. Ayesha Siddika, Takahiro Yamada, Risako Aoyama, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Shigeyoshi Matsumura, Yoshiya Ikawa
Publikováno v:
Molecules, Vol 27, Iss 23, p 8298 (2022)
Naturally occurring ribozymes with a modular architecture are promising platforms for construction of RNA nanostructures because modular redesign enables their oligomerization. The resulting RNA nanostructures can exhibit the catalytic function of th
Externí odkaz:
https://doaj.org/article/88148bfad5224568ad99fe843a67cccd
Autor:
Junya Akagi, Takahiro Yamada, Kumi Hidaka, Yoshihiko Fujita, Hirohide Saito, Hiroshi Sugiyama, Masayuki Endo, Shigeyoshi Matsumura, Yoshiya Ikawa
Publikováno v:
Applied Sciences, Vol 11, Iss 6, p 2583 (2021)
Ribozymes are catalytic RNAs that are attractive platforms for the construction of nanoscale objects with biological functions. We designed a dimeric form of the Tetrahymena group I ribozyme as a unit structure in which two ribozymes were connected i
Externí odkaz:
https://doaj.org/article/1c1b4df7047f471bab46324445d2f37b
Publikováno v:
CHIMIA, Vol 72, Iss 12 (2018)
Ribonuclease P (RNase P) is a class of enzymes involved in the processing of precursor tRNAs to remove their 5'-leader sequences. Ribonuclease P enzymes are classified into two completely distinct classes, i.e. an RNA-based enzyme and a protein-only
Externí odkaz:
https://doaj.org/article/5ce6f91f044749b687858be59a5a4db5
Publikováno v:
Biology, Vol 4, Iss 2, Pp 251-263 (2015)
The effects of cationic porphyrins on the catalytic activities of four group I ribozymes were investigated. A cationic porphyrin possessing four pyridinium moieties (pPyP) inhibited two group IC3 ribozymes (Syn Rz and Azo Rz) and a group IC1 ribozyme
Externí odkaz:
https://doaj.org/article/2902c7ffa2544fee85b84674f88b6aab
Publikováno v:
Biology, Vol 8, Iss 3, p 65 (2019)
The modular structural domains of multidomain RNA enzymes can often be dissected into separate domain RNAs and their noncovalent assembly can often reconstitute active enzymes. These properties are important to understand their basic characteristics
Externí odkaz:
https://doaj.org/article/6425df5fb4e24a20831dd9c240e374df
Publikováno v:
Biology, Vol 6, Iss 4, p 37 (2017)
A bimolecular ribozyme consisting of a core ribozyme (ΔP5 RNA) and an activator module (P5abc RNA) has been used as a platform to design assembled RNA nanostructures. The tight and specific assembly between the P5abc and ΔP5 modules depends on two
Externí odkaz:
https://doaj.org/article/f71a34732b90445a933180f638db15e4
Publikováno v:
Biology, Vol 5, Iss 4, p 43 (2016)
Group I self-splicing intron constitutes an important class of functional RNA molecules that can promote chemical transformation. Although the fundamental mechanism of the auto-excision from its precursor RNA has been established, convenient assay sy
Externí odkaz:
https://doaj.org/article/25c2495b48f3424e93d0cc81a7c2629c
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 40:867-883
While current group I ribozymes use several distinct strategies to function under conditions of low Mg2+ concentration (≤ 3 mM), a deletion mutant of the Tetrahymena ribozyme (ΔP5 ribozyme) is virt...