Zobrazeno 1 - 10
of 441
pro vyhledávání: '"Shigetoshi, CHIBA"'
Autor:
Akishi Momose, Michihiro Yabe, Shigetoshi Chiba, Kenjirou Kumakawa, Yasuo Shiraiwa, Hiroki Mizukami
Background: Expression levels of voltage-dependent T-type calcium channel subunit alfa 1H (Cav3.2), big conductance calcium-activated potassium channel (BKCa), and anoctamin 1 in the skin, including in peripheral nerve endings were previously found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b9ec13dabd6640d9cb35ff4d75494a7
https://doi.org/10.21203/rs.3.rs-2083986/v1
https://doi.org/10.21203/rs.3.rs-2083986/v1
Autor:
Akishi Momose, Michihiro Yabe, Shigetoshi Chiba, Kenjirou Kumakawa, Yasuo Shiraiwa, Hiroki Mizukami
Expression levels of Cav3.2, BKCa, and anoctamin 1 were previously found to be significantly elevated in patients with chronic kidney disease–associated pruritus (CKD-aP). On the other hand, the expression of TRPV1 was significantly reduced. We fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dad877678cce3a0a3f6833f1243ef01
Autor:
Xiao-Ping Yang, Shigetoshi Chiba
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 1, Pp 83-89 (2005)
This study was designed to clarify the α1-adrenoceptor subtypes mediating the vasoconstrictor response to tyramine in isolated and perfused canine splenic artery. It was shown that tyramine potentiated the nerve stimulation-induced second peaked vas
Externí odkaz:
https://doaj.org/article/559199863403435880470efee480d2be
Autor:
Shigetoshi Chiba, Xiao-Ping Yang
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 2, Pp 84-92 (2003)
It has been recognized that sympathetic neurons release several transmitters but mainly adenosine 5'-triphosphate (ATP), noradrenaline, and neuropeptide Y (NPY). Recently, we reported that periarterial nerve electrical stimulation (PNS) produced biph
Externí odkaz:
https://doaj.org/article/b56b597d69f14d1695a031d94f74a5ef
Autor:
Shigetoshi Chiba, Xiao-Ping Yang
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 4, Pp 381-386 (2003)
Effects of olmesartan (RNH-6270: (5-methyl-2-oxo-1,3-dioxolen-4-yl)methoxy-4-(1-hydroxy-1-methylethyl)-2-propyl{4-[2-(tetrazol-5-yl)-phenyl]phenyl}methylimidazol-5-carboxylase, an active form of olmesartan medoxomil (CS-866)) was investigated in isol
Externí odkaz:
https://doaj.org/article/b571eb25e196408fba33614e98422bff
Chronic Kidney Disease–Associated Pruritus is Caused by Dysregulated Ion Channels in Sensory Neurons
Autor:
Hiroki Mizukami, Kenjirou Kumakawa, Shigetoshi Chiba, Michihiko Yabe, Yasuo Shiraiwa, Akishi Momose
Background: We investigated ion channels at the skin, including peripheral nerve endings, which serve as output machines and molecular integrators of many pruritic inputs mainly received by multiple G protein-coupled receptors (GPCRs). Methods: Based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b791e9940426a6b25e068861b823d1
https://doi.org/10.20944/preprints201909.0142.v1
https://doi.org/10.20944/preprints201909.0142.v1
Autor:
Mitiyo Hatanaka, Shigetoshi Chiba, Etsuko Kitano, Kazuo Watanabe, Yasuo Shiraiwa, Taku Nakajima, Kenjirou Kumakawa, Nobuhiro Sasaki, Akishi Momose, Hajime Kitamura
Publikováno v:
Nephron Extra
Nephron Extra, Vol 5, Iss 1, Pp 30-38 (2015)
Nephron Extra, Vol 5, Iss 1, Pp 30-38 (2015)
We present the first report of a case of fibrillary glomerulonephritis (FGN) associated with thrombotic microangiopathy (TMA) and anti-glomerular basement membrane antibody (anti-GBM antibody). A 54-year-old man was admitted to our hospital for high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad10fac793336dc3a4e93c69903dcd51
http://europepmc.org/articles/PMC4376932
http://europepmc.org/articles/PMC4376932
Autor:
Micihihiro Yabe, Hiroki Mizukami, Shigetoshi Chiba, Yasuo Shiraiwa, Kenjirou Kumakawa, Akishi Momose
Publikováno v:
Medicines
Volume 6
Issue 4
Volume 6
Issue 4
Background: We investigated ion channels at the skin, including peripheral nerve endings, which serve as output machines and molecular integrators of many pruritic inputs mainly received by multiple G protein-coupled receptors (GPCRs). Methods: Based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fdd407da20a0d324852cb8c742ee54
https://doi.org/10.3390/medicines6040110
https://doi.org/10.3390/medicines6040110
Autor:
Xiao-Ping, Yang, Shigetoshi, Chiba *
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(4):461-466
Publikováno v:
Journal of Cardiovascular Pharmacology. 53:325-332
Azelnidipine, a dihydropyridine calcium channel blocker unlike other dihydropyridine calcium channel blockers, does not increase but slightly decreases heart rate (HR) in clinical settings. In the present study, the mechanism for the HR-lowering acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e165f718b05fd12a94686d67f79ca9
https://doi.org/10.1097/fjc.0b013e31819f1be1
https://doi.org/10.1097/fjc.0b013e31819f1be1