Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Shigetaka Shimodaira"'
Autor:
Shyng-Shiou F. Yuan, Leong-Perng Chan, Hieu D. H. Nguyen, Chang-Wei Su, Yuk-Kwan Chen, Jeff Yi-Fu Chen, Shigetaka Shimodaira, Stephen Chu‐Sung Hu, Steven Lo, Yen-Yun Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Betel quid and its major ingredient, areca nut, are recognized by IARC as major risk factors in oral cancer development. Areca nut extract (ANE) exposure has been linked to OPMD progression and malignant transformation to OSCC. Ho
Externí odkaz:
https://doaj.org/article/4aa0750bbc754667b88858d4026a6076
Autor:
Machi Suka, Hiroyuki Yanagisawa, Nobuhiro Sato, Shigetaka Shimodaira, Masayuki Saruta, Shigeo Koido, Junichi Taguchi, Masamori Shimabuku, Shin Kan, Tuuse Bito, Takeyuki Misawa, Zensho Ito, Kan Uchiyama, Shintaro Tsukinaga, Toshifumi Ohkusa, Haruo Sugiyama
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background We aimed to develop a chemoimmunotherapy regimen consisting of a novel Wilms’ tumor 1 (WT1) peptide-pulsed dendritic cell (WT1-DC) vaccine and multiagent chemotherapy and to investigate the safety, clinical outcomes, and WT1-specific imm
Externí odkaz:
https://doaj.org/article/3756c5f4da2747fd83b90f8049ea096a
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-6 (2024)
Abstract Background Satisfactory treatment for patients with unresectable advanced lung cancer has not yet been established. We report a case of unresectable advanced lung cancer (stage IIIb: T2aN3M0) treated with a total of 15 doses of dendritic cel
Externí odkaz:
https://doaj.org/article/2a11a13b50cf4c7b849b3e9409165fe7
Autor:
Shintaro Matsuba, Hiroki Ura, Fumiji Saito, Chie Ogasawara, Shigetaka Shimodaira, Yo Niida, Nobuyuki Onai
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Dendritic cells (DCs) are the most potent antigen-presenting cells, playing an essential role in the pathogen and tumor recognition, and anti-tumor immunity, and linking both the innate and adaptive immunity. The monocyte-derived DCs generated by ex
Externí odkaz:
https://doaj.org/article/75d05acbf4464351ad3f4b5073b9296a
Autor:
Hironori Kitajima, Takuya Sakamoto, Tetsuhiro Horie, Ayane Kuwano, Atsushi Fuku, Yasuhiko Taki, Yuka Nakamura, Ikuhiro Tanida, Hiroshi Sunami, Hiroaki Hirata, Yoshiyuki Tachi, Naoki Yamamoto, Yasuo Iida, Yasuhito Ishigaki, Sohsuke Yamada, Shigetaka Shimodaira, Yusuke Shimizu, Toru Ichiseki, Ayumi Kaneuji, Satoshi Osawa, Norio Kawahara
Publikováno v:
Cells, Vol 12, Iss 2, p 330 (2023)
Knee osteoarthritis (Knee OA) is an irreversible condition that causes bone deformity and degeneration of the articular cartilage that comprises the joints, resulting in chronic pain and movement disorders. The administration of cultured adipose-deri
Externí odkaz:
https://doaj.org/article/d2049a19df7241e0845c96e4b928d18d
Autor:
Terutsugu Koya, Yo Niida, Misa Togi, Kenichi Yoshida, Takuya Sakamoto, Hiroki Ura, Sumihito Togi, Tomohisa Kato, Sohsuke Yamada, Haruo Sugiyama, Shigeo Koido, Shigetaka Shimodaira
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12177 (2022)
Malignant pleural effusion (MPE) provides a liquid tumor microenvironment model that includes cancer cells and immune cells. However, the characteristics of tumor antigen-specific CD8+ T cells have not been investigated in detail. Here, we analyzed M
Externí odkaz:
https://doaj.org/article/c9f6cbb35b47492aaea691d1ef076aed
Autor:
Takuya Sakamoto, Terutsugu Koya, Misa Togi, Kenichi Yoshida, Tomohisa Kato, Yasuhito Ishigaki, Shigetaka Shimodaira
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8362 (2022)
Human dendritic cell (DC) dexosomes were evaluated for their function and preclinical validation for vaccines. Dexosomes are small DC-secreted vesicles that contain absorbing immune signals. Vaccine manufacturing requires a significant number of mono
Externí odkaz:
https://doaj.org/article/f2f795298396431d9f215a5531be5ed0
Autor:
Atsushi Fuku, Yasuhiko Taki, Yuka Nakamura, Hironori Kitajima, Takashi Takaki, Terutsugu Koya, Ikuhiro Tanida, Kaori Nozaki, Hiroshi Sunami, Hiroaki Hirata, Yoshiyuki Tachi, Togen Masauji, Naoki Yamamoto, Yasuhito Ishigaki, Shigetaka Shimodaira, Yusuke Shimizu, Toru Ichiseki, Ayumi Kaneuji, Satoshi Osawa, Norio Kawahara
Publikováno v:
Cells, Vol 11, Iss 3, p 337 (2022)
Osteoarthritis (OA) is an irreversible degenerative condition causing bone deformation in the joints and articular cartilage degeneration with chronic pain and impaired movement. Adipose-derived stem cell (ADSC) or crushed adipose tissue injection in
Externí odkaz:
https://doaj.org/article/99f87837d714479b957ca967e859e064
Autor:
Keiichi Sakai, MD, PhD, Shigetaka Shimodaira, MD, PhD, Shinya Maejima, MD, PhD, Kenji Sano, MD, PhD, Yumiko Higuchi, PhD, Terutsugu Koya, MS, Haruo Sugiyama, MD, PhD, Kazuhiro Hongo, MD, PhD
Publikováno v:
Interdisciplinary Neurosurgery, Vol 9, Iss , Pp 24-29 (2017)
Background: Dendritic cells (DCs), which are the most powerful antigen-presenting cells, activate innate and adaptive immune responses. Wilms' tumor 1 (WT1) is a tumor-associated antigen that is frequently expressed in many human cancers including gl
Externí odkaz:
https://doaj.org/article/77b43731600e4e9a9adf4cfda2f2ed1c
Autor:
Hisao Tajiri, Toshifumi Ohkusa, Haruo Sugiyama, Jianlin Gong, Shigetaka Shimodaira, Sei-ichi Yusa, Takefumi Ishidao, Masaki Ito, Yuko Kamata, Hideo Komita, Kazumi Hayashi, Shin Kan, Masahiro Ikegami, Satoru Yanagisawa, Yoichi Toyama, Takeyuki Misawa, Hiroshi Arakawa, Mikio Kajihara, Kan Uchiyama, Hiroo Imazu, Seita Koyama, Shunichi Odahara, Shintaro Tsukinaga, Shinji Yoshizaki, Masako Mori, Kazuki Takakura, Masato Okamoto, Sadamu Homma, Shigeo Koido
Supplementary Figure Legend from Treatment with Chemotherapy and Dendritic Cells Pulsed with Multiple Wilms' Tumor 1 (WT1)–Specific MHC Class I/II–Restricted Epitopes for Pancreatic Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24946cec609875410134b9f63799eb64
https://doi.org/10.1158/1078-0432.22456167.v1
https://doi.org/10.1158/1078-0432.22456167.v1
