Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Shigetaka Nakamura"'
Autor:
Siddhant Sethi, Yasuharu Takashima, Shigetaka Nakamura, Licheng Wan, Nozomi Honda, Kenzo Fujimoto
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 6, Pp 4687-4700 (2023)
Herein, we report the major factor for deamination reaction rate acceleration, i.e., hydrophilicity, by using various 5-substituted target cytosines and by carrying out deamination at high temperatures. Through substitution of the groups at the 5′-
Externí odkaz:
https://doaj.org/article/8887be9d1e7744c0a2cd85c3f4ac0e1c
Publikováno v:
Molecules, Vol 17, Iss 1, Pp 163-178 (2011)
We demonstrated that 5-vinyldeoxyuridine (VU) and 5-carboxyvinyldeoxyuridine (CVU) can be used to photoligate a longer oligonucleotide (ODN) from smaller ODNs on a template. By performing irradiation at 366 nm, these artificial nucleotides make photo
Externí odkaz:
https://doaj.org/article/86796794f9434af180fe6a57e37659b2
Publikováno v:
Molecules, Vol 23, Iss 4, p 828 (2018)
Gene therapies, including genome editing, RNAi, anti-sense technology and chemical DNA editing are becoming major methods for the treatment of genetic disorders. Techniques like CRISPR-Cas9, zinc finger nuclease (ZFN) and transcription activator-like
Externí odkaz:
https://doaj.org/article/c13326976b734d6ea7c3750586a94606
Publikováno v:
Chemistry Letters. 52:273-275
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a4511314fa97720119a572be3a389e2
https://doi.org/10.1246/cl.230055
https://doi.org/10.1246/cl.230055
Publikováno v:
Journal of Chemical Technology & Biotechnology. 97:295-298
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::675884f475cb4913c6d3af5cffd0bb17
https://doi.org/10.1002/jctb.6941
https://doi.org/10.1002/jctb.6941
Publikováno v:
Theoretical Computer Science. 862:193-213
This paper deals with the control problem of right linear grammars with unknown behaviors (RLUBs, for short) in which derivation behavior is not determined completely. In particular, we discuss on the size of control alphabets of control systems whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4e7dc8a55fd797be10651acea081628
https://doi.org/10.1016/j.tcs.2020.11.051
https://doi.org/10.1016/j.tcs.2020.11.051
Publikováno v:
Journal of Chemical Technology & Biotechnology. 97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b16ad6385099981f97ba5577ed0bf81b
https://doi.org/10.1002/jctb.6994
https://doi.org/10.1002/jctb.6994
Publikováno v:
Chembiochem : a European journal of chemical biology. 22(24)
Double duplex invasion (DDI) DNA is a useful antigene method that inhibits expression of genomic DNA. We succeeded in performing photoinduced-DDI (pDDI) using ultrafast photo-cross-linking. 5-Cyanouracil (CN U) has been used in pDDI to inhibit photo-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e73e6c77054e1339f8c8d57099cb1de
https://pubmed.ncbi.nlm.nih.gov/34643012
https://pubmed.ncbi.nlm.nih.gov/34643012
Publikováno v:
Bioorganicmedicinal chemistry letters. 35
Nucleobase editing is a powerful tool in genetic disease therapy. We have reported the photochemical transition of cytosine to uracil using an ultrafast DNA photo-cross-linking. In this study, we used cytosine derivatives such as methylcytosine, hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7008b52f48b0c82d5015656ba26b795e
https://pubmed.ncbi.nlm.nih.gov/33486052
https://pubmed.ncbi.nlm.nih.gov/33486052
Publikováno v:
Chembiochem : a European journal of chemical biology. 21(21)
RNA editing, which is used to edit nucleobases in RNA strands; is more feasible for use in medical applications than DNA editing. We previously reported the photochemical conversion of cytosine to uracil, which required photo-crosslinking, deaminatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc67536df94fec23f47300c762bb932
https://pubmed.ncbi.nlm.nih.gov/32519413
https://pubmed.ncbi.nlm.nih.gov/32519413