Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Shigetaka Koda"'
Publikováno v:
YAKUGAKU ZASSHI. 122:121-125
The Residue on Ignition Test specified in General Tests, Japanese Pharmacopeia is a method to measure the weight of the residual substance not volatilized when the sample is ignited under a constant condition. Generally, this test is intended to dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846ca8ed540e643ce3bf0e58c816d384
https://doi.org/10.1248/yakushi.122.121
https://doi.org/10.1248/yakushi.122.121
Autor:
Yasuhiro Kita, Shigetaka Koda, Yoshimi Hirasawa, Noritugu Morokoshi, Toshio Azuma, Toshihiro Akama, Shinichi Fukuyama
Publikováno v:
Pharmaceutical Research. 13:1238-1242
Purpose. We have recently reported that degradation of FK409 with generation of NO is spontaneous and is accelerated in the presence of sulfhydryl-bearing compounds, such as L-cysteine (Cys) and glutathione (GSH). The purpose of the present study is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b92a44ca3147c0a4cb6f1d72e0cdf86d
https://doi.org/10.1023/a:1016076623060
https://doi.org/10.1023/a:1016076623060
Publikováno v:
Chromatographia. 40:253-258
A high-performance liquid chromatographic (HPLC) method has been developed and validated for the determination of FK506, a new immunosuppressant, in bulk drug samples and dosage forms. Equilibration between FK506 (I) and its tautomeric compounds (II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b19b47bf6f4b76db2c7d2862aafd0664
https://doi.org/10.1007/bf02290354
https://doi.org/10.1007/bf02290354
Publikováno v:
Pharmaceutical Research. 12:1948-1952
Purpose. Recently, we have reported that FK409 spontaneously releases nitric oxide (NO) in solution. In the present study, the influence of L-cysteine (Cys) and glutathione (GSH), which are typical sulfhydryl group-bearing compounds, on NO release fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b97db46f19a6b8c7889e0b10a79534f
https://doi.org/10.1023/a:1016248124104
https://doi.org/10.1023/a:1016248124104
Publikováno v:
Journal of Chromatography A. 590:364-368
Cefixime (CX), an oral cephalosporin antibiotic, and its metabolites in human digestive organs were separated by various modes of high-performance capillary electrophoresis. The zone electrophoresis mode in phosphate buffer (pH 6.8) containing 3-[(3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcbc78685076352140c2aa0bdc221e8
https://doi.org/10.1016/0021-9673(92)85400-n
https://doi.org/10.1016/0021-9673(92)85400-n
Autor:
Shigehiro Takase, Masashi Hashimoto, Toshiji Tada, Shigetaka Koda, Hiroshi Kayakiri, Toshihiro Sibata
Publikováno v:
Chemical and Pharmaceutical Bulletin. 39:1378-1381
The structure of kifunensine, a new immunomodulator produced by a strain of Kitasatosporia, has been estabilished as 1 on the basis of chemical and physicochemical evidence and X-ray crystallographic analysis. Kifunensine is unique both in its novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b510e1b5627a23de105a093b2c362d87
https://doi.org/10.1248/cpb.39.1378
https://doi.org/10.1248/cpb.39.1378
Autor:
Tsutomu Yasuda, Shizuka Yokobayashi, Shigetaka Koda, Mitsue Hara, Teruyuki Kitagawa, Tetsuo Kawabata
Publikováno v:
BUNSEKI KAGAKU. 40:T9-T13
種々の医薬品原体及びそれらの関連物質の水分定量の一手段として,水分気化法を日常分析に適用する際の標準的な試験条件につき検討した.その結果,加熱温度を"150℃"又は"分解点マイナ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1157f6619db734006ad17a5f00567a4f
https://doi.org/10.2116/bunsekikagaku.40.t9
https://doi.org/10.2116/bunsekikagaku.40.t9
Publikováno v:
Journal of Pharmacy and Pharmacology. 42:611-614
A new anti-anginal drug, 6-chloro-2-pyridylmethyl nitrate (FR46171), was found to form a complex with β-cyclodextrin (β-CyD), molecular ratio 1:1. The FR46171/β-CyD complex thus prepared showed a moisture adsorption-desorption hysteresis character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973b36f80b47484e6a5e605fd175d1ef
https://doi.org/10.1111/j.2042-7158.1990.tb06617.x
https://doi.org/10.1111/j.2042-7158.1990.tb06617.x
Publikováno v:
International Journal of Pharmaceutics. 59:217-224
Partially dehydrated cefixime trihydrate was found to be unstable due to a highly disordered crystal structure caused by loss of its water of crystallization. It was also confirmed that cefixime trihydrate stored at a relative humidity below its crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793a01ac4f7af44edc60ef4260d42ac0
https://doi.org/10.1016/0378-5173(90)90112-h
https://doi.org/10.1016/0378-5173(90)90112-h
Publikováno v:
Journal of Pharmaceutical Sciences. 79:189-195
Structural characterization of two polymorphs (Forms A and B) of 8-(2-methoxycarbonylamino-6-methylbenzyloxy)-2-methyl-3-(2-p ropynyl)-imidazo [1,2-a]pyridine (1) was accomplished by X-ray crystallographic analysis. Form A crystallized in the monocli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee97366b71126aaf94895f643c973da9
https://doi.org/10.1002/jps.2600790302
https://doi.org/10.1002/jps.2600790302