Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Shigeru Takasaki"'
Autor:
Shigeru Takasaki
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
This paper first explains how the relations between Japanese Alzheimer’s disease (AD) patients and their mitochondrial SNP frequencies at individual mtDNA positions examined using the radial basis function (RBF) network and a method based on RBF ne
Externí odkaz:
https://doaj.org/article/2343ff8e6f174a2fae0490f212acedca
Autor:
Tomokazu Konishi, Fumikazu Konishi, Shigeru Takasaki, Kohei Inoue, Koji Nakayama, Akihiko Konagaya
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3555 (2008)
A parametric framework for the analysis of transcriptome data is demonstrated to yield coincident results when applied to data acquired using two different microarray platforms. Microarrays are widely employed to acquire transcriptome information, an
Externí odkaz:
https://doaj.org/article/2847ef7781ee437a995a3b2fdca78207
Using decision tree learning to predict the responsiveness of hepatitis C patients to drug treatment
Publikováno v:
FEBS Open Bio
Highlights ► We modeled drug responses using decision tree learning based on SNPs in a genome-wide association study. ► We can predict the drug responses of a new patient with HCV genotype 1. ► Responsiveness to pegylated interferon α (PEG-IFN
Autor:
Shigeru Takasaki
Publikováno v:
Computers in Biology and Medicine. 40:149-158
Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are only a few consistencies among the recently reported design rules/guidelines for sel
Autor:
Shigeru Takasaki
Publikováno v:
Journal of Bioenergetics and Biomembranes. 41:407-410
The relationships between Japanese Alzheimer's disease (AD) patients and their mitochondrial single nucleotide polymorphism (mtSNP) frequencies at individual mtDNA positions of the entire mitochondrial genome are described using the radial basis func
Autor:
Shigeru Takasaki
Publikováno v:
Computational Biology and Chemistry. 33:368-372
Short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells but varies markedly in its gene silencing efficacy. Although many design rules/guidelines for effective siRNAs based on various criteria have been repor
Autor:
Shigeru Takasaki
Publikováno v:
Journal of Genetics and Genomics. 36:425-434
The relationships between five classes of Japanese people (i.e., 96 centenarians, 96 Alzheimer's disease (AD) patients, 96 Parkinson's disease (PD) patients, 96 type 2 diabetic (T2D) patients, and 96 healthy non-obese young males) and their mitochond
Autor:
Shigeru Takasaki
Publikováno v:
Computational Biology and Chemistry. 32:332-337
In this paper we examined the relations between three classes of people (96 Japanese centenarians, 96 Japanese Alzheimer's disease (AD) patients and 96 Japanese Parkinson's disease (PD) patients) and their mitochondrial single nucleotide polymorphism
Autor:
Shigeru Takasaki, Yoshihoro Kawamura
Publikováno v:
Computational Statistics & Data Analysis. 51:6476-6487
Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are only a few consistencies among the recently reported design rules/guidelines for sel
Publikováno v:
Computational Biology and Chemistry. 30:169-178
Short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells but varies markedly in its gene-silencing efficacy. Although many design rules/guidelines for effective siRNAs based on various criteria have been repor