Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shigeru Sakuyama"'
Autor:
Takahiko Nakae, Nobuyuki Hamanaka, Yoshihiko Odagaki, Hisao Nakai, Shigeru Sakuyama, Mitoshi Konno
Publikováno v:
Bioorganic & Medicinal Chemistry. 5:1649-1674
A series of trisubstituted benzenes which demonstrate leukotriene B 4 (LTB 4 , 1 ) receptor affinity was prepared. Previous trisubstituted benzenes from our laboratory showed high affinity to the LTB 4 receptor but demonstrated agonist activity in fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7df63249ca64c1bdd559fc7505bbfa8
https://doi.org/10.1016/s0968-0896(97)00089-8
https://doi.org/10.1016/s0968-0896(97)00089-8
Autor:
Shigeru Sakuyama, Takahiko Nakae, Minoru Nishizaki, Hisao Nakai, Mitoshi Konno, Yoshihiko Odagaki, Nobuyuki Hamanaka
Publikováno v:
Bioorganicmedicinal chemistry. 5(8)
Structural analogues of leukotriene B 4 (LTB 4 ) were designed based on the plausible conformation of LTB 4 ( 1 ). Joining C-7–C-9 of the conformer A or B into an aromatic ring system led to the discovery of benzene analogues 2 , 4 and 6a . Joining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2bb0996b56acee893b022e4b2c56e5
https://pubmed.ncbi.nlm.nih.gov/9313867
https://pubmed.ncbi.nlm.nih.gov/9313867
Autor:
Tai Shiraishi, Yasufumi Kawanaka, Ikuo Shinohara, Takayuki Makihara, Shigeru Sakuyama, Shuichi Ohuchida, Chisa Ohta, Hiroshi Araki, Shin-itsu Kuwabe, Takuya Seko
Publikováno v:
The Journal of Organic Chemistry. 75:1330-1330
An improved synthesis of the highly selective EP4-receptor agonist ONO-4819 has been developed. The previous synthesis suffered from several drawbacks, in which a critical one is the difficulty in the removal of byproducts leading to unsatisfactory q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619fe7fc3fb75d3e11b8d773e19bab96
https://doi.org/10.1021/jo902446x
https://doi.org/10.1021/jo902446x
Autor:
Shigeru Sakuyama
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 21:824-835
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8126f14fc40357c052325b99b2636dae
https://doi.org/10.5059/yukigoseikyokaishi.21.824
https://doi.org/10.5059/yukigoseikyokaishi.21.824
Autor:
Shigeru SAKUYAMA
Publikováno v:
Journal of Japan Oil Chemists' Society. 8:350-355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9907ef06ed304d4c1b7b26da8fb3160d
https://doi.org/10.5650/jos1956.8.350
https://doi.org/10.5650/jos1956.8.350
Autor:
Shigeru SAKUYAMA
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 22:680-683
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::176f836ab10bff22362c57e0e920855f
https://doi.org/10.5059/yukigoseikyokaishi.22.680
https://doi.org/10.5059/yukigoseikyokaishi.22.680
Publikováno v:
Nippon kagaku zassi. 78:981-982
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37c2251ebb59a89e883c783da4147678
https://doi.org/10.1246/nikkashi1948.78.981
https://doi.org/10.1246/nikkashi1948.78.981