Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Shigeru Nakashima"'
Autor:
Yoshikatsu Nakamura, Shigeru Nakashima, Katsuhiro Ojio, Yatsuji Ito, Kazuki Hayakawa, Hideo Miyata, Yoshinori Nozawa
Publikováno v:
Allergology International, Vol 48, Iss 4, Pp 239-245 (1999)
To investigate the possible involvement of cytoskeletal components in antigen (Ag)-mediated activation of phospholipase D (PLD) in rat basophilic leukemia (RBL-2H3) cells, the effects of cytochalasin D, which is known to interfere with actin organiza
Externí odkaz:
https://doaj.org/article/b1832a194a6240cebda41844a9dccfcb
Publikováno v:
Experimental cell research. 367(1)
The Golgi apparatus plays roles in cell polarity, directional cell migration, and bipolar spindle assembly, as well as the secretary pathway. In addition, recent studies have suggested the Golgi-dependent control of mitotic entry. We studied the role
Publikováno v:
Oncology Reports. 32:2359-2364
Lymphatic metastasis of human malignant adenocarcinomas is a critical determinant of prognosis. Lymphangiogenesis, the growth of lymphatic vessels, is closely involved in lymphatic metastasis. However, the mechanisms of tumor lymphangiogenesis are no
Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy
Autor:
Yusuke Egashira, Kentaro Yamashita, Shinichi Yoshimura, Kiyofumi Yamada, Masahiro Tawada, Yoshitaka Tanaka, Shinichiro Hayashi, Hiroshi Mizuno, Shigeru Nakashima, Yuka Ikegame, Fukka You, Toru Iwama
Publikováno v:
Cytotherapy. 13:675-685
Background aims. Transplantation of mesenchymal stromal cells (MSC) derived from bone marrow (BM) or adipose tissue is expected to become a cell therapy for stroke. The present study compared the therapeutic potential of adiposederived stem cells (AS
Autor:
Yuka Ikegame, Toru Iwama, Shigeru Nakashima, Kentaro Yamashita, Shinichi Yoshimura, Shinichiro Hayashi
Publikováno v:
Hypertension Research. 33:703-707
Release of neutrophil elastase is one of the harmful inflammatory reactions in acute cerebral ischemia. Therefore, inhibition of elastase released from neutrophils could be a useful strategy for the treatment of acute stroke. To evaluate this hypothe
Publikováno v:
Neuropathology. 29:20-24
Malignant gliomas are usually incurable even if adjuvant therapy is delivered after neurosurgical treatment. Therefore, to enhance their radiation-induced apoptosis, it is important to detect the mechanism(s) leading to the death of malignant glioma
Autor:
Shigeru Nakashima, Yasuo Kitajima, Hiroyuki Kanoh, Mahmoud A. Ghannoum, Yoko Sugiyama, Yoshinori Nozawa, F. Mirbod
Publikováno v:
Medical Mycology. 37:61-67
Autor:
Shigeru Nakashima, Hideaki Hara, Yoshimi Nakajima, Masamitsu Shimazawa, Yoshinori Kotani, Shinichi Yoshimura, Toru Iwama, Kentaro Yamashita
Publikováno v:
Brain Research. 1154:215-224
Background and purpose Recently, fasudil, a Rho kinase (ROCK) inhibitor, was reported to prevent cerebral ischemia in vivo by increasing cerebral blood flow and inhibiting inflammatory responses. However, it is uncertain whether a ROCK inhibitor can
Publikováno v:
Journal of Cellular Biochemistry. 100:256-265
The immediate early response gene IEX-1 is involved in the regulation of apoptosis and cell growth. In order to increase the apoptotic sensitivity to chemotherapeutic drugs and gamma-ray, we attempted to establish U87-MG human glioma cell line expres
Autor:
Tohru Kiyono, Jun Shinoda, Motoshi Sawada, Toru Iwama, Shigeru Nakashima, Noboru Sakai, Shigeru Hara, Takashi Naganawa
Publikováno v:
Cell Death & Differentiation. 11:997-1008
The present study was designed to examine the roles of p53, reactive oxygen species (ROS), and ceramide, and to determine their mutual relationships during tumor necrosis factor (TNF)-alpha-induced apoptosis of human glioma cells. In cells possessing