Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Shigeru Morishima"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 113, Iss 2, Pp 169-181 (2010)
Two distinct α1-adrenoceptor phenotypes (α1A- and α1L-ARs) are known to originate from a single ADRA1A(α1a) gene by an as-yet-unknown mechanism. We hypothesized that an α1a-AR-interacting protein could generate the α1L-AR phenotype and we sough
Externí odkaz:
https://doaj.org/article/d9eeaffcc05b442b8b17001a14b2901d
Autor:
Hatsumi Yoshiki, Atsushi Nishimune, Fumiko Suzuki, Shigeru Morishima, Takeshi Ikeda, Masato Sasaki, Leslie M. Audigane, Chantal Gauthier, Ikunobu Muramatsu
Publikováno v:
Journal of Pharmacological Sciences, Vol 110, Iss 3, Pp 389-396 (2009)
Abstract.: [3H]-CGP12177 biphasically bound to β-adrenoceptors with high and low affinities in the segments and crude membranes of rabbit left ventricle. The low-affinity sites for [3H]-CGP12177 in the segments was double in density, compared to the
Externí odkaz:
https://doaj.org/article/572ea20b99f342c7bf41425dfb26404d
Autor:
Takahiro Horinouchi, Yumie Miyake, Tadashi Nishiya, Arata Nishimoto, Shigeru Morishima, Ikunobu Muramatsu, Soichi Miwa
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 4, Pp 456-459 (2008)
This study examines the functional role of Na+/H+ exchanger (NHE) in Ca2+ influx mediated by human endothelin type A receptor (ETAR) expressed in Chinese hamster ovary (CHO) cells. Endothelin-1 (ET-1) increased extracellular acidification rate (ECAR)
Externí odkaz:
https://doaj.org/article/edf0b748bb8346a4974571085a02438a
Autor:
Abu Syed Md Anisuzzaman, Shigeru Morishima, Fumiko Suzuki, Takashi Tanaka, Hatsumi Yoshiki, Zakia Sultana Sathi, Hironobu Akino, Osamu Yokoyama, Ikunobu Muramatsu
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 2, Pp 271-279 (2008)
Muscarinic receptors in the human and rat lower urinary tract (urinary bladder detrusor muscle and mucosa, and prostate) were identified by intact tissue segment binding assays with two radioligands, and the effects of prolonged receptor activation i
Externí odkaz:
https://doaj.org/article/79e3ad4da7d34bd0b6938207774b28aa
Autor:
Ikunobu Muramatsu, Takashi Tanaka, Fumiko Suzuki, Zhang Li, Yasuko Hiraizumi-Hiraoka, Abu Syed Md Anisuzzaman, Hatsumi Yamamoto, Takahiro Horinouchi, Shigeru Morishima
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 4, Pp 331-339 (2005)
The radioligand binding assay technique is an extremely powerful tool for studying receptors. It allows an analysis of the interactions of hormones, neurotransmitters, and related drugs with their receptors. Most of the binding assays have widely bee
Externí odkaz:
https://doaj.org/article/2b6371616a404d7187bce4e790014630
Autor:
Yasunobu, Okada, Tomohiro, Numata, Kaori, Sato-Numata, Ravshan Z, Sabirov, Hongtao, Liu, Shin-Ichiro, Mori, Shigeru, Morishima
Publikováno v:
Current topics in membranes. 83
Two types of anion channels are directly activated by osmotic swelling and are involved in the regulatory volume decrease (RVD) in most types of mammalian cells, and they include the volume-sensitive outwardly rectifying anion channel (VSOR), also ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b549a41fb202549b141e3e07d10c0c88
https://pubmed.ncbi.nlm.nih.gov/31196606
https://pubmed.ncbi.nlm.nih.gov/31196606
Autor:
Hong-Tao Liu, Yasunobu Okada, Kaori Sato-Numata, Shigeru Morishima, Shin-ichiro Mori, Ravshan Z. Sabirov, Tomohiro Numata
Two types of anion channels are directly activated by osmotic swelling and are involved in the regulatory volume decrease (RVD) in most types of mammalian cells, and they include the volume-sensitive outwardly rectifying anion channel (VSOR), also ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8053e1617a46af0521bb031540378b7a
https://doi.org/10.1016/bs.ctm.2019.03.001
https://doi.org/10.1016/bs.ctm.2019.03.001
Autor:
Rie Nishi, Katsuya Sakai, Kazutaka Takagi, Toru Nakamura, Shigeru Morishima, Takahiro Yamauchi, Tuneo Tanaka, Mihoko Takai, Takanori Ueda
Publikováno v:
Nephron Extra
Nephron Extra, Vol 3, Iss 1, Pp 73-85 (2013)
Nephron Extra, Vol 3, Iss 1, Pp 73-85 (2013)
Background: Hyperuricemia cases (HU) can be classified into four subgroups by combining the two main causes of hyperuricemia, i.e. urate underexcretion and overproduction. These subgroups are as follows: underexcretion-type cases (UE); overproduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f610df4becb0c071ba82869480581d9
https://doi.org/10.1159/000354029
https://doi.org/10.1159/000354029
Autor:
Shigeru Morishima, Ikunobu Muramatsu, Abu Syed Md Anisuzzaman, Hatsumi Yoshiki, Junsuke Uwada
Publikováno v:
Life Sciences. 93:17-23
Aims Recombinant systems have been used for evaluating the properties of G-protein-coupled receptors (GPCRs) on the assumption of cell surface expression. However, many GPCRs, including muscarinic acetylcholine receptors (mAChRs), have also been repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d828e0f1fbe1af21fd0810b92ad087af
https://doi.org/10.1016/j.lfs.2013.05.013
https://doi.org/10.1016/j.lfs.2013.05.013
Autor:
Shigeru Morishima, Ikunobu Muramatsu, Abu Syed Md Anisuzzaman, T.-H. Su, Fumiko Suzuki, Atsushi Nishimune, Chang Ck, Hatsumi Yoshiki
Publikováno v:
British Journal of Pharmacology. 158:354-360
Background and purpose: The expression of multiple pharmacological phenotypes including α1L-adrenoceptor has recently been reported for α1-adrenoceptors. The purpose of the present study was to identify α1-adrenoceptor phenotypes in the irises of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97cc3b08bff76770ad75339ab95e4c0d
https://doi.org/10.1111/j.1476-5381.2009.00254.x
https://doi.org/10.1111/j.1476-5381.2009.00254.x