Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Shigeru Miyaki"'
Autor:
Tadashi Inoue, Toshiya Kano, Tomoyuki Nakasa, Masakazu Ishikawa, Keiichiro Inoue, Shingo Kawabata, Shigeru Miyaki, Naosuke Kamei, Nobuo Adachi
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Limited healing potential of the meniscus remains a burden for the successful repair of meniscus injuries in the orthopaedic fields. Silk-elastin (SE) is a novel recombinant protein with favorable properties for wound healing. Thi
Externí odkaz:
https://doaj.org/article/ded4ea2d82524765bcce470fd492f55e
Autor:
Kyohei Nakata, Masakazu Ishikawa, Naosuke Kamei, Shigeru Miyaki, Nobuo Adachi, Keiichiro Inoue, Shingo Kawabata
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 180-187 (2024)
Background: Skeletal muscle injury (SMI) is often treated conservatively, although it can lead to scar tissue formation, which impedes muscle function and increases muscle re-injury risk. However, effective interventions for SMIs are yet to be establ
Externí odkaz:
https://doaj.org/article/d30871e5efe74db481a49a9413bfb51c
Autor:
Akinori Nekomoto, Tomoyuki Nakasa, Yasunari Ikuta, Chenyang Ding, Shigeru Miyaki, Nobuo Adachi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Suppressing inflammation and abnormal subchondral bone turnover is essential for reducing osteoarthritis (OA) progression and pain relief. This study focused on calcitonin gene-related peptide (CGRP), which is involved in inflammation and bo
Externí odkaz:
https://doaj.org/article/0707a0537e774aa9812685a5357b0926
Autor:
Yohei Sanada, Yasunari Ikuta, Chenyang Ding, Masahiro Shinohara, Dilimulati Yimiti, Hiroyuki Ishitobi, Keita Nagira, Minjung Lee, Takayuki Akimoto, Sachi Shibata, Masakazu Ishikawa, Tomoyuki Nakasa, Kiminori Matsubara, Martin K. Lotz, Nobuo Adachi, Shigeru Miyaki
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-17 (2022)
Abstract Background Animal models of spontaneous osteoarthritis (OA) are sparse and not well characterized. The purpose of the present study is to examine OA-related changes and mechanisms in senescence-accelerated mouse prone 8 (SAMP8) that displays
Externí odkaz:
https://doaj.org/article/858d78eac3ea481294fd92a47106f8d7
Autor:
Yuji Tsuchikawa, Naosuke Kamei, Yohei Sanada, Toshio Nakamae, Takahiro Harada, Kazunori Imaizumi, Takayuki Akimoto, Shigeru Miyaki, Nobuo Adachi
Publikováno v:
Neural Plasticity, Vol 2023 (2023)
Several microRNAs (miRNAs), including miR-23 and miR-27a have been reportedly involved in regulating myelination in the central nervous system. Although miR-23 and miR-27a form clusters in vivo and the clustered miRNAs are known to perform complement
Externí odkaz:
https://doaj.org/article/38605a65d28840bead0c570769ec147f
Autor:
Yusuke Fujiwara, Chenyang Ding, Yohei Sanada, Dilimulati Yimiti, Masakazu Ishikawa, Tomoyuki Nakasa, Naosuke Kamei, Kazunori Imaizumi, Martin K. Lotz, Takayuki Akimoto, Shigeru Miyaki, Nobuo Adachi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Osteoarthritis (OA), the most prevalent aging-related joint disease, is characterized by insufficient extracellular matrix synthesis and articular cartilage degradation and is caused by various risk factors including aging and traumatic injury. Most
Externí odkaz:
https://doaj.org/article/d12359d04f2849089895d50e27a71bbe
Autor:
Takenori Omoto, Dilimulati Yimiti, Yohei Sanada, Minoru Toriyama, Chenyang Ding, Yuta Hayashi, Yasunari Ikuta, Tomoyuki Nakasa, Masakazu Ishikawa, Masayuki Sano, Minjung Lee, Takayuki Akimoto, Chisa Shukunami, Shigeru Miyaki, Nobuo Adachi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Tendon is a fibrous connective tissue, that is, transmitting the forces that permit body movement. However, tendon/ligament biology is still not fully understood and especially, the role of miRNAs in tendon/ligament is sparse and uncharacterized in i
Externí odkaz:
https://doaj.org/article/af9fa7052f93483fa724fe98b65a079f
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 419 (2021)
Osteoarthritis (OA) is a common aging-associated disease that clinically manifests as joint pain, mobility limitations, and compromised quality of life. Today, OA treatment is limited to pain management and joint arthroplasty at the later stages of d
Externí odkaz:
https://doaj.org/article/ab89e7a31a2046908529f39672b614f6
Autor:
Chenyang Ding, Dilimulati Yimiti, Yohei Sanada, Yuki Matsubara, Tomoyuki Nakasa, Kiminori Matsubara, Nobuo Adachi, Shigeru Miyaki
Publikováno v:
Modern Rheumatology; Jul2024, Vol. 34 Issue 4, p831-840, 10p
Autor:
Yuichi Kato, Tomoyuki Nakasa, Junichi Sumii, Munekazu Kanemitsu, Masakazu Ishikawa, Shigeru Miyaki, Nobuo Adachi
Publikováno v:
CARTILAGE. 14:247-255
Objective Articular cartilage defect causes joint pain and finally progresses to osteoarthritis. Although the subchondral bone condition affects clinical outcomes of cartilage defects, the natural course of changes in subchondral bone and associated