Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Shigeru MATSUKURA"'
Autor:
Hideyuki Kobayashi, Hiroki Yokoo, Akihiko Wada, Shin-ichi Minami, Ryuichi Yamamoto, Seiji Shiraishi, Takeshi Kurose, Toshihiko Yanagita, Shigeru Matsukura
Publikováno v:
Journal of Neurochemistry. 75:672-682
Our previous study showed that treatment of cultured bovine adrenal chromaffin cells with phorbol 12, 13-dibutyrate (PDBu) or 12-O-tetradecanoylphorbol 13-acetate (TPA) caused a rapid ( 15 h) translocation of both conventional (c) protein kinase C-α
Autor:
Masatoshi Tokojima, Kouji Matsushima, Shigeki Katoh, Yukifumi Nawa, Jun-ichi Ashitani, Shigeru Matsukura, Kiyoshi Matsumoto, Nobuhiro Matsumoto, Fukumi Nakamura-Uchiyama
Publikováno v:
International Archives of Allergy and Immunology. 134:248-252
Background: Paragonimiasis westermani (Pw), a common parasitic zoonosis in Asia, is typically associated with eosinophilia. Th2 cytokines seem to have an important role in the clinical manifestations of this disease. Thymus and activation-regulated c
Autor:
Nobuatsu Nagai, Daisuke Yasuhara, Masamitsu Nakazato, Yoshiki Tatebe, Shigeru Matsukura, Tetsuro Naruo, Tomomi Shiiya, Shin-ichi Nozoe, Muneki Tanaka
Publikováno v:
Psychoneuroendocrinology. 28:829-835
Ghrelin has a role in regulating eating behavior and energy metabolism in the central nervous system, and has been reported to play an important role in the pathophysiology of anorexia nervosa (AN). The aim of the present study was to compare fasting
Autor:
Masamitsu Nakazato, Shigeru Matsukura
Publikováno v:
Geriatrics & Gerontology International. 3:113-119
Background: The authors have established that missense mutations of the transthyretin gene cause middle age onset of familial systemic amyloidosis. The purpose of the present study was to investigate molecular abnormalities of the serum protein, tran
Autor:
Kumiko Kawakita, Akira Tominaga, Shigeki Katoh, Paul W. Kincade, Nobuhiro Matsumoto, Shigeru Matsukura
Publikováno v:
Journal of Clinical Investigation. 111:1563-1570
Previous studies established that IL-5-producing CD4(+) T cells play a pivotal role in allergic respiratory inflammation. It was also reported that CD4(+) T cells express higher levels of CD44 in the airway than in peripheral blood of patients with a
Autor:
Arisa Sano, Shigeru Matsukura, Hirotoshi Iiboshi, Yoshifumi Imadsu, Koh Abe, Hiroshi Mukae, Shigehisa Yanagi
Publikováno v:
Internal Medicine. 42:88-91
A 19-year-old womanpresented with acute onset of cough and dyspnea. She started smoking two weeks before the appearance of symptoms. On admission, arterial blood gas analysis on room air breathing revealed PaO2 55 Torr. Chest roentgenogram and high r
Publikováno v:
European Journal of Pharmacology. 458:227-234
This study aimed to investigate the effect of long-term oral nicotine administration on insulin resistance in an animal model of obesity. Eight-week-old male Zucker fatty rats (ZFRs) were administered nicotine tartrate dihydrate (4.6 mg/kg/day) in th
Autor:
Tomomi Shiiya, Masamitsu Nakazato, Shigeru Matsukura, Nobutaka Kuroki, Muneki Tanaka, Tetsuro Naruo, Shin-ichi Nozoe, Nobuatsu Nagai
Publikováno v:
Journal of Psychiatric Research. 37:17-22
Previous studies have reported that fasting plasma ghrelin concentrations play an important role in the pathophysiology of eating disorders. The purpose of this study was to examine the relationship between plasma ghrelin levels and frequency of abno
Autor:
Jun-ichi Kadota, Masamitsu Nakazato, H Iiboshi, Masatoshi Tokojima, Takeaki Hiratsuka, Shigeru Matsukura, Hiroshi Mukae, Shigeru Kohno, Jun-ichi Ashitani, Kuniko Abe
Publikováno v:
Thorax. 57:623-628
Background: Neutrophils are thought to play an important role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Human neutrophils contain antimicrobial and cytotoxic peptides in the azurophil granules which belong to a family of mammalian n