Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Shigeru Kigoshi"'
Autor:
Shigeru Kigoshi, Takehisa Saito, Yoshiaki Nojyo, Yoko Kohno, Ikunobu Muramatsu, Hitoshi Saito, Hirohiko Aoyama
Publikováno v:
British Journal of Pharmacology. 116:2557-2562
1. Neurogenic responses to transmural electrical stimulation were examined in endothelium-denuded extrameningeal (vertebral and carotid) and intrameningeal (spinal, basilar and middle cerebral) arteries isolated from dogs. 2. In the extrameningeal ar
Publikováno v:
Pharmacology Biochemistry and Behavior. 50:225-232
Effects of chronic treatment with propranolol or atenolol on stress-induced changes in blood pressure, body weight, and cerebral beta-adrenoceptors in rats were examined and compared with the effects of chronic treatment with prazosin. Immobilization
Publikováno v:
General Pharmacology: The Vascular System. 25:1221-1228
1. Plasma endothelin-1 level as well as plasma lipid and glucose levels was markedly elevated in the rats treated with streptozotocin 8 weeks earlier. 2. Positive inotropic response, which was significantly greater than that in the age-matched contro
Publikováno v:
British Journal of Pharmacology. 112:1167-1173
1. We determined the alpha 1-adrenoceptor subtypes involved in adrenergic contractions of eight different blood vessels isolated from the dog. 2. Noradrenaline produced concentration-dependent contractions in all the blood vessels tested, which were
Publikováno v:
Japanese Journal of Pharmacology. 66:191-194
Electrical transmural stimulation of isolated iris dilator muscle of the rabbit produced a transient contraction that consisted of adrenergic and nonadrenergic components. In contrast to the adrenergic component, the nonadrenergic component was resis
Publikováno v:
Journal of Receptor Research. 14:75-98
The alpha 1-adrenoceptor subtypes in rat lung were characterized according to their binding of [3H]-prazosin or [3H]-WB4101 and were compared with that in rat liver. [3H]-prazosin bound with high affinity to an apparently homogeneous population of si
Publikováno v:
Japanese Circulation Journal. 58:278-284
Cold preservation of isolated mammalian hearts attenuates cardiac contractility. We examined the effect of intracellular and extracellular Ca ion on the contractility of cold-preserved atria of rat. Rat hearts were isolated and stored in Collins' sol
Publikováno v:
Pharmacology Biochemistry and Behavior. 45:623-627
Effects of chronic treatment with bevantolol, a beta-adrenoceptor blocker, and of repeated immobilization stress on blood pressure, body weight, and [3H]dihydroalprenolol ([3H]DHA) binding to the cerebral cortex were examined in rats. Systolic blood
Publikováno v:
British Journal of Pharmacology. 108:1071-1076
1. alpha 1-Adrenoceptor subtypes in rabbit thoracic aorta have been examined in binding and functional experiments. 2. [3H]-prazosin bound to two distinct populations of alpha 1-adrenoceptors (pKD,high = 9.94, Rhigh = 79.2 fmol mg-1 protein; pKD,low
Publikováno v:
European Journal of Pharmacology. 231:209-214
In the presence of adrenergic and cholinergic blocking agents, transmural electrical stimulation evoked a relaxation in isolated dog urethra precontracted with histamine. The response was abolished by tetrodotoxin, indicating its neurogenic origin. T