Zobrazeno 1 - 10
of 1 463
pro vyhledávání: '"Shigeru KOHNO"'
Autor:
Taiga Miyazaki, Naoki Hosogaya, Yuri Fukushige, Sachiko Takemori, Shinpei Morimoto, Hiroshi Yamamoto, Makoto Hori, Yoshihito Ozawa, Yuki Shiko, Yosuke Inaba, Tomoya Kurokawa, Hideki Hanaoka, Shoya Iwanami, Kwangsu Kim, Shingo Iwami, Koichi Watashi, Ken Miyazawa, Takashi Umeyama, Satoshi Yamagoe, Yoshitsugu Miyazaki, Takaji Wakita, Makoto Sumiyoshi, Tatsuro Hirayama, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae, Hitoshi Kawasuji, Yoshihiro Yamamoto, Norihito Tarumoto, Hiroshi Ishii, Hideaki Ohno, Kazuhiro Yatera, Hiroshi Kakeya, Yoshiko Kichikawa, Yasuyuki Kato, Tetsuya Matsumoto, Makoto Saito, Hiroshi Yotsuyanagi, Shigeru Kohno
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Nelfinavir, an orally administered inhibitor of human immunodeficiency virus protease, inhibits the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro. We conducted a randomized controlled trial to evaluate
Externí odkaz:
https://doaj.org/article/0a380e871da94f7abcec22d99a173a53
Autor:
Kenji Ota, Satoshi Murakami, Kaori Ishihara, Daisuke Sasaki, Tetsuya Usui, Fujiko Mitsumoto-Kaseida, Kei Sakamoto, Kosuke Kosai, Hiroo Hasegawa, Takahiro Takazono, Akitsugu Furumoto, Norichika Asoh, Hiroyuki Yoshimine, Toyomitsu Sawai, Masanari Onizuka, Noriaki Makimoto, Koichi Izumikawa, Hiroshi Mukae, Shigeru Kohno, Katsunori Yanagihara
Publikováno v:
Vaccine: X, Vol 13, Iss , Pp 100282- (2023)
The IgG antibody titer against SARS-CoV-2 receptor binding protein (RBD) after mRNA vaccine were compared between those with and without previous infection (PI) for up to 48 weeks. Though sustained higher IgG-RBD were observed in the PI group after t
Externí odkaz:
https://doaj.org/article/9cc2282932a24138bde395a690375fed
Autor:
Haruka Maeda, Eiichiro Sando, Michiko Toizumi, Yuzo Arima, Tomoe Shimada, Takeshi Tanaka, Masato Tashiro, Ayumi Fujita, Katsunori Yanagihara, Hayato Takayama, Ikkoh Yasuda, Nobuyuki Kawachi, Yoshitaka Kohayagawa, Maiko Hasegawa, Katsuaki Motomura, Rie Fujita, Katsumi Nakata, Jiro Yasuda, Koichi Morita, Shigeru Kohno, Koichi Izumikawa, Motoi Suzuki, Konosuke Morimoto
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 9, Pp 2251-2260 (2021)
In April 2020, a coronavirus disease (COVID-19) outbreak occurred on the cruise ship Costa Atlantica in Nagasaki, Japan. Our outbreak investigation included 623 multinational crewmembers onboard on April 20. Median age was 31 years; 84% were men. Eac
Externí odkaz:
https://doaj.org/article/4780b6a4e7564f388ae10a4e6dc704c4
Autor:
Maiko Kiyohara, Taiga Miyazaki, Michiyo Okamoto, Tatsuro Hirayama, Koichi Makimura, Hiroji Chibana, Nana Nakada, Yuya Ito, Makoto Sumiyoshi, Nobuyuki Ashizawa, Kazuaki Takeda, Naoki Iwanaga, Takahiro Takazono, Koichi Izumikawa, Katsunori Yanagihara, Shigeru Kohno, Hiroshi Mukae
Publikováno v:
Journal of Fungi, Vol 9, Iss 5, p 529 (2023)
Outbreaks of invasive infections, with high mortality rates, caused by multidrug-resistant Candida auris have been reported worldwide. Although hotspot mutations in FKS1 are an established cause of echinocandin resistance, the actual contribution of
Externí odkaz:
https://doaj.org/article/609dd914f49948b5aa9ec68582cb7c74
Autor:
Naoki Hosogaya, Taiga Miyazaki, Yuri Fukushige, Sachiko Takemori, Shinpei Morimoto, Hiroshi Yamamoto, Makoto Hori, Tomoya Kurokawa, Yohei Kawasaki, Michiko Hanawa, Yasuhisa Fujii, Hideki Hanaoka, Shingo Iwami, Koichi Watashi, Satoshi Yamagoe, Yoshitsugu Miyazaki, Takaji Wakita, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae, Shigeru Kohno, Nelfinavir Study Group
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-4 (2021)
Abstract Objectives The aim of this trial is to evaluate the antiviral efficacy, clinical efficacy, and safety of nelfinavir in patients with asymptomatic and mild COVID-19. Trial design The study is designed as a multicenter, open-label, blinded out
Externí odkaz:
https://doaj.org/article/4598a03cd9b7436ea3330cedc3fc097b
Autor:
Shoya Iwanami, Keisuke Ejima, Kwang Su Kim, Koji Noshita, Yasuhisa Fujita, Taiga Miyazaki, Shigeru Kohno, Yoshitsugu Miyazaki, Shimpei Morimoto, Shinji Nakaoka, Yoshiki Koizumi, Yusuke Asai, Kazuyuki Aihara, Koichi Watashi, Robin N Thompson, Kenji Shibuya, Katsuhito Fujiu, Alan S Perelson, Shingo Iwami, Takaji Wakita
Publikováno v:
PLoS Medicine, Vol 18, Iss 7, p e1003660 (2021)
BackgroundDevelopment of an effective antiviral drug for Coronavirus Disease 2019 (COVID-19) is a global health priority. Although several candidate drugs have been identified through in vitro and in vivo models, consistent and compelling evidence fr
Externí odkaz:
https://doaj.org/article/516b82537a63450ab8a2bac11a255a96
Autor:
Kenji Ota, Katsunori Yanagihara, Daisuke Sasaki, Norihito Kaku, Naoki Uno, Kei Sakamoto, Kosuke Kosai, Taiga Miyazaki, Hiroo Hasegawa, Ayumi Fujita, Masato Tashiro, Takeshi Tanaka, Koichi Izumikawa, Koya Ariyoshi, Hiroshi Mukae, Jiro Yasuda, Kouichi Morita, Shigeru Kohno
Publikováno v:
PLoS ONE, Vol 16, Iss 6 (2021)
Objectives The accurate detection of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) is essential for the diagnosis of coronavirus disease 2019 (COVID-19). We compared the quantitative RT-PCR results between nasopharyngeal swabs and sa
Externí odkaz:
https://doaj.org/article/80f6ea28a147426ba5a8928f6416ca19
Autor:
Norihito Kaku, Fumitaka Nishimura, Yui Shigeishi, Rina Tachiki, Hironori Sakai, Daisuke Sasaki, Kenji Ota, Kei Sakamoto, Kosuke Kosai, Hiroo Hasegawa, Koichi Izumikawa, Koya Ariyoshi, Hiroshi Mukae, Jiro Yasuda, Kouichi Morita, Shigeru Kohno, Katsunori Yanagihara
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257452 (2021)
ObjectivesA few studies on antibody testing have focused on asymptomatic or mild coronavirus disease 2019 (COVID-19) patients with low initial anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody responses. Anti-SARS-CoV-2 antib
Externí odkaz:
https://doaj.org/article/18fcd44e2308427499a00527bb297f2a
Autor:
Mineaki Kitamura, Hideyuki Arai, Shinichi Abe, Yuki Ota, Kumiko Muta, Akira Furusu, Hiroshi Mukae, Shigeru Kohno, Tomoya Nishino
Publikováno v:
SAGE Open Medicine, Vol 8 (2020)
Objectives: Although angiotensin II receptor blockers are effective for patients with chronic kidney disease, dose-dependent renoprotective effects of angiotensin II receptor blockers in patients with moderate to severe chronic kidney disease with no
Externí odkaz:
https://doaj.org/article/f130c6ab4acd4996b61079deb080f2c6
Autor:
Haruka Abe, Yuri Ushijima, Murasaki Amano, Yasuteru Sakurai, Rokusuke Yoshikawa, Takaaki Kinoshita, Yohei Kurosaki, Katsunori Yanagihara, Koichi Izumikawa, Kouichi Morita, Shigeru Kohno, Jiro Yasuda
Publikováno v:
Microorganisms, Vol 10, Iss 1, p 99 (2022)
In the initial phase of the novel coronavirus disease (COVID-19) pandemic, a large-scale cluster on the cruise ship Diamond Princess (DP) emerged in Japan. Genetic analysis of the DP strains has provided important information for elucidating the poss
Externí odkaz:
https://doaj.org/article/50557964a0c74ade9fc6bec21e824948