Zobrazeno 1 - 10
of 383
pro vyhledávání: '"Shigeru Goto"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9331 (2024)
Since the first published report of experimental kidney transplantation in dogs in 1902, there were many experimental and clinical trials of organ transplantation, with many sacrifices. After the establishment of the surgical technique and the discov
Externí odkaz:
https://doaj.org/article/24865bbfe6ab4e8289698d75a9ba8b1f
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract The importance of sun exposure on human health is well recognized, and a recent trend in the avoidance of sun exposure has led to the risk of missing the beneficial effects such as vitamin D3 biogenesis. Vitamin D3 insufficiency is one of th
Externí odkaz:
https://doaj.org/article/9911b503c5094fe0b3926e8d90dc10a7
Autor:
Toshiaki Nakano, Chao-Long Chen, I-Hsuan Chen, Hui-Peng Tseng, Kuei-Chen Chiang, Chia-Yun Lai, Li-Wen Hsu, Shigeru Goto, Chih-Che Lin, Yu-Fan Cheng
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7908 (2023)
Accumulating evidence suggests the involvement of tumor-derived exosomes in the development and recurrence of hepatocellular carcinoma (HCC). We previously identified miR-4669 as a highly expressed microRNA in circulating exosomes obtained from patie
Externí odkaz:
https://doaj.org/article/9c924aab9a1e4dc98c3d1fb517ffc798
Autor:
Kuang-Tzu Huang, I-Ying Kuo, Ming-Chao Tsai, Chun-Hsien Wu, Li-Wen Hsu, Li-Yu Chen, Chao-Pin Kung, Yu-Fan Cheng, Shigeru Goto, Yu-Wei Chou, Chao-Long Chen, Chih-Che Lin, Kuang-Den Chen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 274-283 (2017)
Hepatocellular carcinoma (HCC) is one of the most common and aggressive malignancies worldwide. Treatment outcomes remain poor mainly due to lack of good diagnostic/prognostic markers and limited therapeutic strategies. We previously characterized ab
Externí odkaz:
https://doaj.org/article/48e5dc56d831470086092efeab740567
Autor:
Kuang-Tzu Huang, Kuang-Den Chen, Li-Wen Hsu, Chao-Pin Kung, Shu-Rong Li, Chien-Chih Chen, King-Wah Chiu, Shigeru Goto, Chao-Long Chen
Publikováno v:
Nutrients, Vol 12, Iss 1, p 270 (2020)
Non-alcoholic fatty liver disease (NAFLD), the leading cause of chronic liver diseases worldwide, ranges from simple steatosis to steatohepatitis, with the risk for progressive fibrosis or even cirrhosis. While simple steatosis is a relatively benign
Externí odkaz:
https://doaj.org/article/cfc3c848219946d080008184944b20f4
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Acute rejection (AR) and spontaneous tolerance may occur after allograft orthotopic liver transplants (OLT) performed in certain combinations of donor and recipient rat strains, yet the underlying molecular cascades involved in these conditions remai
Externí odkaz:
https://doaj.org/article/3d9104b116ef4bad8e4696b91ff165f2
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3992 (2018)
Adipogenesis is a tightly regulated cellular process that involves the action of multiple signaling pathways. Characterization of regulators that are associated with adipose development is crucial to understanding the mechanisms underlying obesity an
Externí odkaz:
https://doaj.org/article/7645112647604cd693897adc807e6bd1
Autor:
Toshiaki Nakano, Rikiya Kamei, Takashi Fujimura, Yuki Takaoka, Ayane Hori, Chia-Yun Lai, Kuei-Chen Chiang, Yayoi Shimada, Naoya Ohmori, Takeshi Goto, Kazuhisa Ono, Chao-Long Chen, Shigeru Goto, Seiji Kawamoto
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153630 (2016)
Nuclear antigens are known to trigger off innate and adaptive immune responses. Recent studies have found that the complex of nucleic acids and core histones that are derived from damaged cells may regulate allergic responses. However, no fundamental
Externí odkaz:
https://doaj.org/article/5c45d65d19de4d9ea7d996fe684eedb9
Autor:
King-Wah Chiu, Toshiaki Nakano, Kuang-Den Chen, Chih-Che Lin, Tsung-Hui Hu, Shigeru Goto, Chao-Long Chen
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156846 (2016)
To investigate the effect of IL28B single nucleotide polymorphisms (SNPs) (rs8099917 and rs12979860) in the donors and recipients on the outcome of Hepatitis C virus-RNA clearance after living donor liver transplantation (LDLT). The rs8099917 and rs1
Externí odkaz:
https://doaj.org/article/3f8316f7fbc84e3c806fa41a43401c61
Autor:
Kuang-Den Chen, Kuang-Tzu Huang, Chih-Che Lin, Wei-Teng Weng, Li-Wen Hsu, Shigeru Goto, Toshiaki Nakano, Chia-Yun Lai, Chao-Pin Kung, King-Wah Chiu, Chih-Chi Wang, Yu-Fan Cheng, Yen-Ying Ma, Chao-Long Chen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Adipose-derived mesenchymal stem cells (ASCs) are readily available multipotent mesenchymal progenitor cells and have become an attractive therapeutic tool for regenerative medicine. We herein investigated the mechanistic role of how miR-27b modulate
Externí odkaz:
https://doaj.org/article/8f95474b8c884e7eb027f82ccd0774da