Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Shigeru Chaen"'
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162003 (2016)
During muscle contraction, myosin heads (M) bound to actin (A) perform power stroke associated with reaction, AMADPPi → AM + ADP + Pi. In this scheme, A • M is believed to be a high-affinity complex after removal of ATP. Biochemical studies on ex
Externí odkaz:
https://doaj.org/article/c04639604dc449a2abafabc759811cbe
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 5, p 1368 (2018)
The most straightforward way to get information on the performance of individual myosin heads producing muscle contraction may be to record their movement, coupled with ATP hydrolysis, electron-microscopically using the gas environmental chamber (EC)
Externí odkaz:
https://doaj.org/article/3c54dfcdadf147eaaa2a27f8ae619308
Autor:
Haruo Sugi, Shigeru Chaen, Takakazu Kobayashi, Takahiro Abe, Kazushige Kimura, Yasutake Saeki, Yoshiki Ohnuki, Takuya Miyakawa, Masaru Tanokura, Seiryo Sugiura
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e93272 (2014)
Muscle contraction results from attachment-detachment cycles between myosin heads extending from myosin filaments and actin filaments. It is generally believed that a myosin head first attaches to actin, undergoes conformational changes to produce fo
Externí odkaz:
https://doaj.org/article/b660b70887ab47b89d8007d3e3edab4b
Autor:
Haruo Sugi, Takahiro Abe, Takakazu Kobayashi, Shigeru Chaen, Yoshiki Ohnuki, Yasutake Saeki, Seiryo Sugiura
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63658 (2013)
Although evidence has been presented that, at low ionic strength, myosin heads in relaxed skeletal muscle fibers form linkages with actin filaments, the effect of low ionic strength on contraction characteristics of Ca(2+)-activated muscle fibers has
Externí odkaz:
https://doaj.org/article/7c08b0b84bc24eca8e460f59fd7e88b9
Publikováno v:
Biophysics and Physicobiology
The myosin II SH1 helix is a joint that links the converter subdomain to the rest of the myosin motor domain and possibly plays a key role in the arrangement of the converter/lever arm. Several point mutations within the SH1 helix in human myosin IIs
Autor:
Naoko Kakusho, Seiji Matsumoto, Rino Fukatsu, Yutaka Kanoh, Shigeru Chaen, Hisao Masai, Shunsuke Kobayashi
Publikováno v:
Molecular and Cellular Biology
Rif1 is a key factor for spatiotemporal regulation of DNA replication. Rif1 suppresses origin firing in the mid-late replication domains by generating replication-suppressive chromatin architecture and by recruiting a protein phosphatase.
Rif1 i
Rif1 i
Autor:
Ryosuke Yamagishi, Hiroki Kaneko, Shigeru Chaen, Shuntaro Oba, Jiro Shimada, Takahide Okuyama
Publikováno v:
Biochemistry and Biophysics Reports
Most transcription and epigenetic factors in eukaryotic cells have nuclear localization signals (NLSs) and are transported to the nucleus by nuclear transport proteins. Understanding the features of NLSs and the mechanisms of nuclear transport might
Publikováno v:
Micron (Oxford, England : 1993). 113
Publikováno v:
Micron (Oxford, England : 1993). 112
Although more than 50 years have passed since the monumental discovery of Huxley and Hanson that muscle contraction results from relative sliding between actin and myosin filaments, coupled with ATP hydrolysis, the mechanism underlying the filament s