Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Shigeru B H Ko"'
Autor:
Yukiko Kuroda, Kenta Maruyama, Hideki Fujii, Isamu Sugawara, Shigeru B H Ko, Hisataka Yasuda, Hidenori Matsui, Koichi Matsuo
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146544 (2016)
Osteoprotegerin (OPG), a decoy receptor for receptor activator of NF-κB ligand (RANKL), antagonizes RANKL's osteoclastogenic function in bone. We previously demonstrated that systemic administration of lipopolysaccharide (LPS) to mice elevates OPG l
Externí odkaz:
https://doaj.org/article/c7fe118a43da431faca26153b807a1b0
Autor:
Yasuhiro Kato, Takayuki Miyauchi, Youichiro Abe, Dušan Kojić, Manami Tanaka, Nana Chikazawa, Yuhki Nakatake, Shigeru B H Ko, Daisuke Kobayashi, Akihiro Hazama, Shoko Fujiwara, Tatsuya Uchida, Masato Yasui
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87644 (2014)
Freezing is usually used for preservation and storage of biological samples; however, this process may have some adverse effects such as cell membrane damage. Aquaporin (AQP), a water channel protein, has been suggested to play some roles for cryopre
Externí odkaz:
https://doaj.org/article/ac2af77b557f4d9faa197845245e98a0
Autor:
Tomohiko Akiyama, Saeko Sato, Shigeru B. H. Ko, Osamu Sano, Sho Sato, Masayo Saito, Hiroaki Nagai, Minoru S. H. Ko, Hidehisa Iwata
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 4, Pp 572-581 (2021)
Abstract Gaucher disease, the most prevalent metabolic storage disorder, is caused by mutations in the glucocerebrosidase gene GBA1, which lead to the accumulation of glucosylceramide (GlcCer) in affected cells. Gaucher disease type 1 (GD1), although
Externí odkaz:
https://doaj.org/article/78f55af7e0164003bcf214e45756fb37
Autor:
Hideomi Ida, Tomohiko Akiyama, Keiichiro Ishiguro, Sravan K. Goparaju, Yuhki Nakatake, Nana Chikazawa-Nohtomi, Saeko Sato, Hiromi Kimura, Yukihiro Yokoyama, Masato Nagino, Minoru S. H. Ko, Shigeru B. H. Ko
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-10 (2018)
Abstract Background Transplantation of pancreatic β cells generated in vitro from pluripotent stem cells (hPSCs) such as embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) has been proposed as an alternative therapy for diabetes.
Externí odkaz:
https://doaj.org/article/2d82226ca15a41c395522aebc3a4c712
Autor:
Tomohiko Akiyama, Saeko Sato, Nana Chikazawa-Nohtomi, Atsumi Soma, Hiromi Kimura, Shunichi Wakabayashi, Shigeru B. H. Ko, Minoru S. H. Ko
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Direct generation of skeletal muscle cells from human pluripotent stem cells (hPSCs) would be beneficial for drug testing, drug discovery, and disease modelling in vitro. Here we show a rapid and robust method to induce myogenic differentiat
Externí odkaz:
https://doaj.org/article/5d62cce54ee541739436beee7b392604
Autor:
Kazuhiro Kashiwagi, Minoru S.H. Ko, Yasushi Hirota, Ichiro Kawada, Norio Goda, Masahiro Hashimoto, Hiroshi Itoh, Shigeru B. H. Ko, Yasushi Iwao, Kanako Makino, Hiromasa Takaishi, Masahiro Jinzaki, Ryoko Shimizu-Hirota
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
The overall effect of lifestyle habits, such as alcohol consumption, on general health remains controversial and it is important to clarify how such habits affect aging-related health impairments. To discover novel impacts of lifestyle on general hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212c92e6e281350f86c73e050bf761ac
https://doaj.org/article/7dd7fe65f14c4962b8e49d6f419ea692
https://doaj.org/article/7dd7fe65f14c4962b8e49d6f419ea692
Autor:
Hiroaki Nagai, Shigeru B. H. Ko, Masayo Saito, Saeko Sato, Osamu Sano, Tomohiko Akiyama, Minoru S.H. Ko, Hidehisa Iwata, Sho Sato
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 4, Pp 572-581 (2021)
Stem Cells Translational Medicine, Vol 10, Iss 4, Pp 572-581 (2021)
Gaucher disease, the most prevalent metabolic storage disorder, is caused by mutations in the glucocerebrosidase gene GBA1, which lead to the accumulation of glucosylceramide (GlcCer) in affected cells. Gaucher disease type 1 (GD1), although defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256aad67d4de364472b92a22ed24445f
http://europepmc.org/articles/PMC7980209
http://europepmc.org/articles/PMC7980209
Autor:
Shigeru B. H. Ko, Saeko Sato, Hiromi Kimura, Yuhki Nakatake, Tomohiko Akiyama, Nana Chikazawa-Nohtomi, Hideomi Ida, Kei-ichiro Ishiguro, Sravan Kumar Goparaju, Masato Nagino, Minoru S.H. Ko, Yukihiro Yokoyama
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-10 (2018)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Transplantation of pancreatic β cells generated in vitro from pluripotent stem cells (hPSCs) such as embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) has been proposed as an alternative therapy for diabetes. Though ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04983d9f8f290f34946fc9c8050c1e9
http://link.springer.com/article/10.1186/s13287-018-1038-3
http://link.springer.com/article/10.1186/s13287-018-1038-3
Autor:
Chikara Furusawa, Hisanori Kiryu, Minoru S.H. Ko, Hirotaka Matsumoto, Norio Gouda, Shigeru B. H. Ko, Itoshi Nikaido, Tetsutaro Hayashi
Publikováno v:
Bioinformatics
The analysis of RNA-Seq data from individual differentiating cells enables us to reconstruct the differentiation process and the degree of differentiation (in pseudo-time) of each cell. Such analyses can reveal detailed expression dynamics and functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c1b579af901b69ef754c903f5b0f4a
https://doi.org/10.1093/bioinformatics/btx194
https://doi.org/10.1093/bioinformatics/btx194
Autor:
Takaharu Kondo, Shigeru B. H. Ko, Yoshiro Sohma, Hiroshi Ishiguro, Kieran Smallbone, Martin C. Steward, Makoto Yamaguchi, Akiko Yamamoto
Publikováno v:
The Journal of Physiology. 595:1947-1972
Key points The ductal system of the pancreas secretes large volumes of alkaline fluid containing HCO3- concentrations as high as 140 mm during hormonal stimulation. A computational model has been constructed to explore the underlying ion transport me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb5b20fc7ba4bdb0fd07f7df1c11d6c2
https://doi.org/10.1113/jp273306
https://doi.org/10.1113/jp273306