Zobrazeno 1 - 10
of 477
pro vyhledávání: '"Shigeru, Hirano"'
Publikováno v:
Acta Oto-Laryngologica Case Reports, Vol 9, Iss 1, Pp 41-46 (2024)
Angiosarcoma is a rare malignant tumor, even rarer particularly in the head and neck. It is considered a very aggressive neoplasm with high rates of local recurrence and a poor prognosis. We report a case of nasal angiosarcoma in which the patient un
Externí odkaz:
https://doaj.org/article/157432fd338b45cfbdbd7ffb2b3adfd7
Autor:
Takahiro Tsujikawa, Kazuchika Ohno, Kei-ichi Morita, Sumiyo Saburi, Junichi Mitsuda, Kanako Yoshimura, Alisa Kimura, Hiroki Morimoto, Hiroshi Ogi, Saya Shibata, Takumi Akashi, Morito Kurata, Issei Imoto, Yasushi Shimizu, Satoshi Kano, Akihito Watanabe, Tomoko Yamazaki, Yukinori Asada, Ryuichi Hayashi, Yuki Saito, Hiroyuki Ozawa, Kiyoaki Tsukahara, Nobuhiko Oridate, Daisuke Sano, Arata Horii, Yushi Ueki, Takashi Maruo, Nobuaki Mukoyama, Nobuhiro Hanai, Takahito Fukusumi, Hiroshi Iwai, Takuo Fujisawa, Takashi Fujii, Ken-ichi Nibu, Shigemichi Iwae, Tsutomu Ueda, Nobuyuki Chikuie, Ryuji Yasumatsu, Mioko Matsuo, Hirohito Umeno, Takeharu Ono, Muneyuki Masuda, Satoshi Toh, Kyoko Itoh, Shigeru Hirano, Takahiro Asakage
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIn view of improving biomarkers predicting the efficacy of immunotherapy for head and neck squamous cell carcinoma (R/M HNSCC), this multicenter retrospective study aimed to identify clinical, tumor microenvironmental, and genomic factors t
Externí odkaz:
https://doaj.org/article/b5c525023e134051b6b1b1fa136b47f3
Autor:
Keiko Hashimoto, Yoichiro Sugiyama, Mami Kaneko, Shota Kinoshita, Ryota Yamamoto, Tomoya Ishida, Toshiro Umezaki, Shigeru Hirano
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionSwallowing impairment is a crucial issue that can lead to aspiration, pneumonia, and malnutrition. Animal models are useful to reveal pathophysiology and to facilitate development of new treatments for dysphagia caused by many diseases. T
Externí odkaz:
https://doaj.org/article/f7c3cfe469e94469b4c1e3f1dff36ecb
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Inner ear macrophages play a vital role in cochlear homeostasis. Recent studies have demonstrated the existence of macrophages at different sites of the cochlea, with increased cochlear infiltration as an inflammatory response mechanism to injury. Ho
Externí odkaz:
https://doaj.org/article/8d0e6d9e732c494c9ba10500c875cc26
Autor:
Hiroki Ishii, Takahiro Tsujikawa, Naoki Oishi, Arisa Kinouchi, Kaname Sakamoto, Junichi Mitsuda, Hiroshi Ogi, Kyoko Itoh, Tetsuo Kondo, Shigeru Hirano, Daiju Sakurai
Publikováno v:
Clinical Case Reports, Vol 10, Iss 7, Pp n/a-n/a (2022)
Abstract Metastatic intrathyroid thymic carcinoma (ITTC) is a rare cancer with no effective drugs for controlling. This case report has shown genomic and immune microenvironment profiles in metastatic ITTC and emphasized an immunosuppression via a PD
Externí odkaz:
https://doaj.org/article/d373a705f9384055b200dd210b07c07e
Publikováno v:
Journal of International Advanced Otology, Vol 17, Iss 5, Pp 465-467 (2021)
Externí odkaz:
https://doaj.org/article/54a07b57b0aa4d1eaf78b179897750b4
Autor:
Toshiaki Numajiri, MD, PhD, Daiki Morita, MD, Akihito Arai, MD, PhD, Takahiro Tsujikawa, MD, PhD, Shigeru Hirano, MD, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 10, Iss 1, p e4017 (2022)
Externí odkaz:
https://doaj.org/article/d8a475da6dcf4e9e87e6abdbbc721a38
Autor:
Kanako Yoshimura, Takahiro Tsujikawa, Junichi Mitsuda, Hiroshi Ogi, Sumiyo Saburi, Gaku Ohmura, Akihito Arai, Saya Shibata, Guillaume Thibault, Young Hwan Chang, Daniel R. Clayburgh, Satoru Yasukawa, Aya Miyagawa-Hayashino, Eiichi Konishi, Kyoko Itoh, Lisa M. Coussens, Shigeru Hirano
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundFunctional interactions between immune cells and neoplastic cells in the tumor immune microenvironment have been actively pursued for both biomarker discovery for patient stratification, as well as therapeutic anti-cancer targets to improve
Externí odkaz:
https://doaj.org/article/0dd2889cd18447c9a68d337c9bbb7a5b
Autor:
Junichi Mitsuda, Takahiro Tsujikawa, Kanako Yoshimura, Sumiyo Saburi, Masaho Suetsugu, Kayo Kitamoto, Mari Takenaka, Gaku Ohmura, Akihito Arai, Hiroshi Ogi, Kyoko Itoh, Shigeru Hirano
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Recent advances made in treatment for head and neck squamous cell carcinoma (HNSCC) highlight the need for new prediction tools to guide therapeutic strategies. In this study, we aimed to develop a HNSCC-targeting multiplex immunohistochemical (IHC)
Externí odkaz:
https://doaj.org/article/928af1fba9714bfdbf99965f04d7cb3b
Autor:
Michiyo Hayakawa, J. Nicholas Taylor, Ryuta Nakao, Kentaro Mochizuki, Yuki Sawai, Kosuke Hashimoto, Koji Tabata, Yasuaki Kumamoto, Katsumasa Fujita, Eiichi Konishi, Shigeru Hirano, Hideo Tanaka, Tamiki Komatsuzaki, Yoshinori Harada
Publikováno v:
Biochemical and biophysical research communications. 640:192-201
Follicular neoplasms of the thyroid include follicular thyroid carcinoma (FTC) and follicular thyroid adenoma (FTA). However, the differences in cytological findings between FTC and FTA remain undetermined. Here, we aimed to evaluate the accumulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ffd5cd3617cc0f7ac40c96cd5bff46
http://hdl.handle.net/2115/88150
http://hdl.handle.net/2115/88150