Zobrazeno 1 - 10 of 281 pro vyhledávání: '"Shigeori, Takenaka"'
1
Akademický článek
Fluorescence Imaging of Extracellular Potassium Ion Using Potassium Sensing Oligonucleotide
Autor: Shinobu Sato, Shinsuke Ohzawa, Kojiro Sota, Naoto Sakamoto, Ayano Udo, Shinji Sueda, Tomoki Matsuda, Takeharu Nagai, Shigeori Takenaka
Publikováno v: Frontiers in Chemistry, Vol 10 (2022)
Potassium-sensing oligonucleotide, PSO, a conjugate of a quadruplex structure-forming oligonucleotide with a peptide incorporating a Förster Resonance Energy Transfer (FRET) chromophore pair, has been developed for fluorescent detection of potassium
Externí odkaz: https://doaj.org/article/6a69215114ee4190ab007caa488467ef
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2
Akademický článek
Naphthalene Diimides Carrying Two β-Cyclodextrins Prefer Telomere RNA G-Quadruplex Recognition
Autor: Tingting Zou, Yuka Sato, Shuma Kaneyoshi, Kota Mano, Rui Yasukawa, Yoshifumi Nakano, Satoshi Fujii, Shinobu Sato, Shigeori Takenaka
Publikováno v: Molecules, Vol 27, Iss 13, p 4053 (2022)
Newly synthesized naphthalene diimide carrying two β-cyclodextrins (NDI-β-CyDs) showed improved specificity for the parallel G-quadruplex structure alongside the hybrid G-quadruplex structure. Specifically, the highest binding affinity of NDI-β-Cy
Externí odkaz: https://doaj.org/article/7dd24898801a47e9a35907bae12dec8b
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3
Akademický článek
Replication Control of Human Telomere G-Quadruplex DNA by G-Quadruplex Ligands Dependent on Solution Environment
Autor: Shuntaro Takahashi, Sudipta Bhowmik, Shinobu Sato, Shigeori Takenaka, Naoki Sugimoto
Publikováno v: Life, Vol 12, Iss 4, p 553 (2022)
The human telomere region is known to contain guanine-rich repeats and form a guanine-quadruplex (G4) structure. As telomeres play a role in the regulation of cancer progression, ligands that specifically bind and stabilize G4 have potential therapeu
Externí odkaz: https://doaj.org/article/f510d65bca504f679f670aabd52e8725
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6
Akademický článek
The Interaction of Cyclic Naphthalene Diimide with G-Quadruplex under Molecular Crowding Condition
Autor: Tingting Zou, Shinobu Sato, Rui Yasukawa, Ryusuke Takeuchi, Shunsuke Ozaki, Satoshi Fujii, Shigeori Takenaka
Publikováno v: Molecules, Vol 25, Iss 3, p 668 (2020)
G-quadruplex specific targeting molecules, also termed as G4 ligands, are attracting increasing attention for their ability to recognize and stabilize G-quadruplex and high potentiality for biological regulation. However, G4 ligands recognizing G-qua
Externí odkaz: https://doaj.org/article/84887cdf613d4e56a77405c98524c915
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7
Akademický článek
A Selective G-Quadruplex DNA-Stabilizing Ligand Based on a Cyclic Naphthalene Diimide Derivative
Autor: Md. Monirul Islam, Satoshi Fujii, Shinobu Sato, Tatsuo Okauchi, Shigeori Takenaka
Publikováno v: Molecules, Vol 20, Iss 6, Pp 10963-10979 (2015)
A cyclic naphthalene diimide (cyclic NDI, 1), carrying a benzene moiety as linker chain, was synthesized and its interaction with G-quadruplex DNAs of a-core and a-coreTT as a human telomeric DNA, c-kit and c-myc as DNA sequence at promoter region, o
Externí odkaz: https://doaj.org/article/2c83ed6380a44269a969f3e8f615e7b3
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9
Akademický článek
Highly Sensitive Nuclease Assays Based on Chemically Modified DNA or RNA
Autor: Shinobu Sato, Shigeori Takenaka
Publikováno v: Sensors, Vol 14, Iss 7, Pp 12437-12450 (2014)
Nucleolytic enzymes are associated with various diseases, and several methods have been developed for their detection. DNase expression is modulated in such diseases as acute myocardial infarction, transient myocardial ischemia, oral cancer, stomach
Externí odkaz: https://doaj.org/article/6498abea3cd0410fb0de13bb44d61633
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