Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Shigeo Yokose"'
Autor:
Atsushi Hakura, Hajime Sui, Yuki Seki, Jiro Sonoda, Yusaku Yoshida, Hisayoshi Takagi, Shigeo Yokose, Tomonari Matsuda, Shoji Asakura, Takehiko Nohmi
Publikováno v:
Genes and Environment, Vol 45, Iss 1, Pp 1-13 (2023)
Abstract Background Chronic inflammation induces DNA damage and promotes cell proliferation, thereby increasing the risk of cancer. DNA polymerase κ (Pol κ), involved in translesion DNA synthesis, counteracts mutagenesis induced by inflammation in
Externí odkaz:
https://doaj.org/article/1d4b7a9880354c08aa90a424771b9d3a
Autor:
Kenichi Masumura, Tomoko Ando, Akiko Ukai, Sho Fujiwara, Shigeo Yokose, Xinyue You, Takayoshi Suzuki, Hiroyuki Hayashi, Takehiko Nohmi, Hisayoshi Takagi, Masamitsu Honma
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-12 (2021)
Abstract Background Gene mutation assays in transgenic rodents are useful tools to investigate in vivo mutagenicity in a target tissue. Using a lambda EG10 transgene containing reporter genes, gpt delta transgenic mice and rats have been developed to
Externí odkaz:
https://doaj.org/article/d36d5fcbf94e4113beef74e2f5e7d3f1
Autor:
Masayuki Mori, Toshihiko Gonda, Hiromitsu Kimura, Hidekazu Asai, Katsunori Sato, Norio Masui, Tetsu Nishikawa, Yumie Takagi, Makoto Yanabe, Shigeo Yokose
Publikováno v:
Experimental Animals. 53:399-407
The congenitally athymic nude rat is used for studying cancer and transplantation owing to its hairlessness and T-cell defective function caused by the Foxn1(rnu) gene. However, NK cell activity of the nude rat is markedly increased. It is known that