Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Shigeo Otake"'
Publikováno v:
Cancer Science
E‐cadherin, an epithelial cell–specific cell adhesion molecule, has both promoting and suppressing effects on tumor invasion and metastasis. It is often downregulated during cancer progression through gene deletion/mutation, transcriptional repre
Autor:
Takashi, Yokoyama, Takahito, Kuga, Yuka, Itoh, Shigeo, Otake, Chiho, Omata, Masao, Saitoh, Keiji, Miyazawa
Publikováno v:
Journal of Biological Chemistry. 299:102820
In mammalian cells, Smad2 and Smad3, two receptor-regulated Smad proteins, play crucial roles in the signal transmission of transforming growth factor-β (TGF-β) and are involved in various cell regulatory processes, including epithelial-mesenchymal
Autor:
Shigeo Otake, Min Kyun Park
Publikováno v:
Reproduction. 152:575-589
Gonadal sex differentiation proceeds by the interplay of various genes including the transcription factors and secretory factors in a complex network. The sex-differentiating genes are expressed not only during early sex differentiation but also thro
Autor:
Masafumi Yamamoto, Yoshimitsu Abiko, Toshirou Kondoh, Koichi Hiratsuka, Yukiko Koizumi, Shigeo Otake, Naomi Ogura, Hiroyuki Okada, Hirotsugu Yamamoto, Mana Ichimura
Publikováno v:
International Journal of Oral-Medical Sciences. 3:143-148
Oral lichen planus (OLP) is a common chronic inflammatory disease of oral mucosa ; however, the precise mechanisms for the formation of OLP have not been elucidated. Laser microdissection is a useful tool for the isolation of target cells from tissue
Autor:
Yoshimitsu Abiko, Masafumi Yamamoto, Mitsuo Hayakawa, Satomi Maeba, Shigeo Otake, Jun Namikoshi
Publikováno v:
International Journal of Oral-Medical Sciences. 3:67-74
Porphyromonus gingivalis is a major pathogen of chronic periodontitis. An outer membrane protein with a molecular mass of 40-kDa (40k-OMP) is a highly immunogenic surface protein produced by P. gingivalis. In this study, to develop an effective vacci
Publikováno v:
International Journal of Oral-Medical Sciences. 3:34-40
Transcutaneous immunization is a new method of vaccination that utilizes a topical application of antigen to intact skin for induction of immune responses. In this study, we have assessed the potential for the application of transcutaneous immunizati
Publikováno v:
FEMS Immunology & Medical Microbiology. 35:43-47
The hemolysin from Prevotella intermedia was partially purified from culture supernatant and then characterized. The hemolysin produced a clear beta-hemolytic zone on a blood agar plate. Hemolytic activity was 2.5-fold greater in culture supernatant
Autor:
Mitsuo Hayakawa, Yoshimitsu Abiko, Masafumi Yamamoto, Satomi Maeba, Shigeo Otake, Jun Namikoshi
Publikováno v:
International Journal of Oral-Medical Sciences. 1:90-96
It is well established that Porphyromonas gingivalis is one of the major pathogens of adult periodontitis. P. gingivalis produces an outer membrane protein with a molecular mass of 40-kDa (40k-OMP). In the present study, in order to assess the potent
Publikováno v:
Journal of Periodontal Research. 37:433-438
The purpose of this study was to determine the usefulness of green tea catechin for the improvement of periodontal disease. The minimum inhibitory concentration (MIC) and bactericidal activity of green tea catechin against black-pigmented, Gram-negat
Publikováno v:
Scandinavian Journal of Immunology. 53:211-217
Cholera toxin (CT) and heat-labile toxin (LT) of Escherichia coli act as adjuvants for the enhancement of mucosal and serum antibody (Ab) responses to mucosally co-administered protein antigen (Ag). Both LT and CT induce B7-2 expression on antigen-pr