Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Shigeo Masuda"'
Autor:
Yujiro Tanaka, Tamako Ikeda, Yukiko Kishi, Shigeo Masuda, Hiroaki Shibata, Kengo Takeuchi, Makoto Komura, Tadashi Iwanaka, Shin-Ichi Muramatsu, Yasushi Kondo, Kazutoshi Takahashi, Shinya Yamanaka, Yutaka Hanazono M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 18 (2009)
The ERas gene promotes the proliferation of and formation of teratomas by mouse embryonic stem (ES) cells. However, its human orthologue is not expressed in human ES cells. This implies that the behavior of transplanted mouse ES cells would not accur
Externí odkaz:
https://doaj.org/article/312fba9eb3194ce18f76a485f3ee5e38
Autor:
Yukiko Kishi, Yujiro Tanaka, Hiroaki Shibata, Shinichiro Nakamura, Koichi Takeuchi, Shigeo Masuda, Tamako Ikeda, Shin-Ichi Muramatsu, Yutaka Hanazono M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 17 (2008)
Embryonic stem (ES) cells have the ability to generate teratomas when transplanted into immunodeficient mice, but conditions affecting the generation remain to be elucidated. Nonhuman primate cynomolgus ES cells were transplanted into immunodeficient
Externí odkaz:
https://doaj.org/article/4cc697d9df0a49cc870c8f93a0defd87
Autor:
Noriko Fukuhara, Dai Maruyama, Kiyohiko Hatake, Hirokazu Nagai, Shinichi Makita, Kenjiro Kamezaki, Toshiki Uchida, Shigeru Kusumoto, Junya Kuroda, Chisako Iriyama, Masamitsu Yanada, Norifumi Tsukamoto, Youko Suehiro, Hironobu Minami, Jose Garcia-Vargas, Barrett H. Childs, Masanobu Yasuda, Shigeo Masuda, Toshiaki Tsujino, Yui Terao, Kensei Tobinai
Publikováno v:
International Journal of Hematology. 117:100-109
The safety, efficacy, and pharmacokinetics of copanlisib were evaluated in this phase Ib/II study in Japanese patients with relapsed/refractory indolent non-Hodgkin lymphoma (NHL). The primary endpoint was safety at the recommended dose; efficacy end
Autor:
Satsuki Fukushima, Maki Takeda, Hiroko Iseoka, Atsuhiro Saito, Shigeo Masuda, Shigeru Miyagawa, Jong-Kook Lee, Emiko Ito, Shin Yajima, Nagako Sougawa, Akima Harada, Yoshiki Sawa
Publikováno v:
Tissue Engineering. Part A
Although engineered cardiac tissues (ECTs) derived from induced pluripotent stem cells (iPSCs) are promising for myocardial regenerative therapy, the appropriate ratio of cardiomyocytes to non-cardiomyocytes is not fully understood. Here, we determin
Autor:
Takuji Kawamura, Noriko Mochizuki-Oda, Shigeru Miyagawa, Satsuki Fukushima, Yoshiki Sawa, Yukiko Imanishi, Shigeo Masuda
Publikováno v:
Current Medicinal Chemistry
Advanced cardiac failure is a progressive intractable disease and is the main cause of mortality and morbidity worldwide. Since this pathology is represented by a definite decrease in cardiomyocyte number, supplementation of functional cardiomyocytes
Publikováno v:
The Lancet. Oncology. 17(9)
According to a recent Review in The Lancet Oncology, only two antibody–drug conjugates have been approved by the US Food and Drug Administration (FDA)—brentuximab vedotin and ado-trastuzumab emtansine. Brentuximab vedotin was approved in 2011 and
Autor:
Satsuki Fukushima, Tadashi Watabe, Shigeo Masuda, Noriyuki Kashiyama, Takuji Kawamura, Jun Hatazawa, Eiichi Morii, Koichi Toda, Shigeru Miyagawa, Ai Kawamura, Emiko Ito, Yoshiki Sawa
Publikováno v:
Scientific Reports
Transplantation of induced pluripotent stem cell-derived cardiac tissue constructs is a promising regenerative treatment for cardiac failure: however, its tumourigenic potential is concerning. We hypothesised that the tumourigenic potential may be el
Autor:
Kengo Takeuchi, Takashi Yokoo, Shigeo Masuda, Masako Doi, Eiji Kobayashi, Shuh-hei Fujishiro, Yutaka Hanazono, Naomi Sugimoto
Publikováno v:
Cell Medicine. 3:103-112
Teratoma formation assays are established methods for evaluating the pluripotency of embryonic stem (ES) cells and induced pluripotent stem (iPS) cells. Teratoma formation in immunodeficient mice takes approximately 2 months. Here, we have developed
Autor:
Yoshiki Sawa, Atsuhiro Saito, Hiroko Iseoka, Shigeo Masuda, Emiko Ito, Jong-Kook Lee, Shin Yajima, Satsuki Fukushima, Shigeru Miyagawa
Publikováno v:
Circulation. 132
Background: It has been shown that transplantation of engineered cardiac tissue (ECT) derived from human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) into the infarct heart induces electrical communication between the ECT and the
Autor:
Shigeru Miyagawa, Yoshiki Sakai, Satsuki Fukushima, Shigeo Masuda, Atsuhiro Saito, Koichi Toda, Yoshiki Sawa
Publikováno v:
Circulation. 132
Background: Although drugs such as beta blockers are reported to be effective for dilated cardiomyopathy (DCM), they are only effective in selected patients, and new therapeutics based on different mechanisms are still needed. We hypothesized that sy