Výsledky vyhledávání - "Shigeo Kachi"

Akademický článek

High rate of awarding compensation for claims of injuries related to clinical trials by pharmaceutical companies in Japan: a questionnaire survey.

Autor: Chieko Kurihara, Hideo Kusuoka, Shunsuke Ono, Naoko Kakee, Kazuyuki Saito, Kenji Takehara, Kiyokazu Tsujide, Yuzo Nabeoka, Takuya Sakuhiro, Hiroshi Aoki, Noriko Morishita, Chieko Suzuki, Shigeo Kachi, Emiko Kondo, Yukiko Komori, Tetsu Isobe, Shigeru Kageyama, Hiroshi Watanabe

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e84998 (2014)

IntroductionInternational norms and ethical standards have suggested that compensation for research-related injury should be provided to injured research volunteers. However, statistical data of incidence of compensation claims and the rate of awardi

Externí odkaz: https://doaj.org/article/9d6898591b834b34bab7c245b383573c

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Informed Consent Training with Simulated Patients for Clinical Research Coordinator Trainees

Autor: Hisako Kume, Hiroshi Yamada, Mitsuko Morita, Shigeo Kachi, Emiko Otobe, Hiroshi Watanabe, Hisakuni Hashimoto, Yoko Saito, Kanako Goto, Noriyo Eguchi, Michiko Kimura, Kazuo Umemura, Nobuhiko Takai, Kyoichi Ohashi, Miyuki Katsumata

Publikováno v: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 36:209-213

Background: From the aspect of biomedical ethics, informed consent is essential for the participant's protection in clinical trials. Informed consent is a process of information disclosure, confirming the participant's understanding and autonomy-driv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bdf4940d85019b106757b0db52bd87ce
https://doi.org/10.3999/jscpt.36.4_209

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IN VIVO EVALUATION OF COMBINATION EFFECTS OF CHLOROQUINE WITH CEPHARANTHIN OR MINOCYCLINE HYDROCHLORIDE AGAINST BLOOD-INDUCED CHLOROQUINE-RESISTANT PLASMODIUM BERGHEI NK 65 INFECTIONS

Autor: Takako Hasegawa, Shigeo Kachi, Hwang-Huei Wang, Akira Ishih, Mamoru Terada, Tohru Suzuki

Publikováno v: Tropical Medicine and Health. 32:15-19

The combination effects of chloroquine with Cepharanthin® or minocycline hydrochloride were evaluated against a blood-induced infection with chloroquine-resistant P. berghei NK 65 in ICR mice. The infected mice in an untreated control group showed a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ede080c50950b03aa815211166de5dc
https://doi.org/10.2149/tmh.32.15

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High Rate of Awarding Compensation for Claims of Injuries Related to Clinical Trials by Pharmaceutical Companies in Japan: A Questionnaire Survey

Autor: Hideo Kusuoka, Yuzo Nabeoka, Shigeo Kachi, Emiko Kondo, Kiyokazu Tsujide, Kazuyuki Saito, Hiroshi Watanabe, Shigeru Kageyama, Yukiko Komori, Tetsu Isobe, Noriko Morishita, Takuya Sakuhiro, Chieko Kurihara, Chieko Suzuki, Kenji Takehara, Shunsuke Ono, Naoko Kakee, Hiroshi Aoki

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e84998 (2014)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfb748604c193bc76d8fae0239c44c5
http://europepmc.org/articles/PMC3885663

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Effects of PF1022A on adultAngiostrongylus cantonensis in the pulmonary arteries and larvae migrating into the central nervous system of rats

Autor: Akira Ishih, Shigeo Kachi, Mamoru Terada

Publikováno v: Parasitology Research. 81:631-637

We examined the effects of PF1022A, newly developing in Japan, on adult Angiostrongylus cantonensis in the pulmonary arteries of rats. Following five and ten successive oral doses at 10 mg/kg per day, the first-stage larvae in rat faeces disappeared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadd7591986dc3b498f90b4eadb501a7
https://doi.org/10.1007/bf00931838

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Effects of amorphous and polymorphs of PF1022A, a new antinematode drug, on Angiostrongylus costaricensis in mice

Autor: Mamoru Terada, Shigeo Kachi, Hisakuni Hashimoto

Publikováno v: Japanese journal of pharmacology. 77(3)

To enhance the bioavailability of PF1022A (cyclo(D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-met hylleucyl-D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N- methylleucyl)), a newly developed antinematode drug, we examined whether the new drug has po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f14fc6c84b91832fb7cb3f1821ef51
https://pubmed.ncbi.nlm.nih.gov/9717771

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Influence of PF1022A on the motility of Angiostrongylus cantonensis in vitro

Autor: Shigeo Kachi, Mamoru Terada, Hisakuni Hashimoto

Publikováno v: Parasitology research. 83(6)

Our previous in vivo studies on angiostrongyliasis showed that PF1022A had stronger killing effects against female adults than against males. No killing effects were observed against young adult worms in the central nervous system. To characterize th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5ce0abd1409e28364df461c314e571
https://pubmed.ncbi.nlm.nih.gov/9211510

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