Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Shigeo Takashima"'
Autor:
Teiko Komori Nomura, Satoshi Endo, Takuma Kuwano, Kazuya Fukasawa, Shigeo Takashima, Tomoki Todo, Kyoji Furuta, Takuhei Yamamoto, Eiichi Hinoi, Hiroko Koyama, Ryo Honda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract ARL-17477 is a selective neuronal nitric oxide synthase (NOS1) inhibitor that has been used in many preclinical studies since its initial discovery in the 1990s. In the present study, we demonstrate that ARL-17477 exhibits a NOS1-independent
Externí odkaz:
https://doaj.org/article/5fd4ae3a30b748479ef5c6520c76f7b8
Autor:
Ryoka Nakanishi, Shigeo Takashima, Yoshiko Wakihara, Yuji O. Kamatari, Yuko Kitamura, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
Publikováno v:
Journal of Dairy Science, Vol 105, Iss 6, Pp 5370-5380 (2022)
ABSTRACT: Enzootic bovine leukosis (EBL) is a B-cell lymphosarcoma caused by bovine leukemia virus (BLV) infection. In Japan, cattle diagnosed with EBL are not permitted for human consumption by the law, thereby causing serious economic losses to far
Externí odkaz:
https://doaj.org/article/c64dfb9aac4d4c7dbe7817e872b29ce1
Autor:
Md. Matiur Rahman, Hinata Ishikawa, Marika Yamauchi, Shigeo Takashima, Yuji O. Kamatari, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
Publikováno v:
Pathogens, Vol 12, Iss 10, p 1239 (2023)
This study aimed to characterize the mRNA signature of milk small extracellular vesicles (sEVs) from BLV-infected cattle. A total of 23 mRNAs, which showed greater abundance in milk sEVs from BLV-infected cattle compared to those from BLV-uninfected
Externí odkaz:
https://doaj.org/article/6c380ad174cc406f8fe25608a70b6dee
Autor:
Yoshinori Kakino, Tomoaki Doi, Hideshi Okada, Kodai Suzuki, Chihiro Takada, Hiroyuki Tomita, Hirotaka Asano, Soichiro Kano, Yugo Wakayama, Tomoki Okuda, Hirotsugu Fukuda, Ayane Nishio, Yuki Kawasaki, Ayumi Kuroda, Takuto Shimada, Shigeo Takashima, Keiko Suzuki, Genki Yoshimura, Ryo Kamidani, Ryu Yasuda, Tetsuya Fukuta, Yuichiro Kitagawa, Haruka Okamoto, Takahito Miyake, Akio Suzuki, Takahiro Yoshida, Nobuyuki Tetsuka, Shozo Yoshida, Shinji Ogura
Publikováno v:
Heliyon, Vol 8, Iss 11, Pp e11262- (2022)
Introduction: Myocardial dysfunction occurs in patients with sepsis due to vascular endothelial injury. Recombinant human thrombomodulin (rhTM) attenuates vascular endothelial injuries through endothelial glycocalyx (eGC) protection. Hypothesis: We h
Externí odkaz:
https://doaj.org/article/9a168a2f892547dfb2bf89cfb5b1d710
Autor:
Md. Matiur Rahman, Shigeo Takashima, Yuji O. Kamatari, Yassien Badr, Yuko Kitamura, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Milk small extracellular vesicles (sEV) contain proteins that provide potential information of host physiology and immunology. Bovine leukemia virus (BLV) is an oncogenic virus that causes progressive B-cell lymphosarcoma in cattle. In this
Externí odkaz:
https://doaj.org/article/fa747610073e4c6fae0a4a7309151148
Autor:
Kotaro Hama, Yuko Fujiwara, Shigeo Takashima, Yasuhiro Hayashi, Atsushi Yamashita, Nobuyuki Shimozawa, Kazuaki Yokoyama
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 4, Pp 523-536 (2020)
X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder caused by deleterious mutations in the ABCD1 gene. The ABCD1 protein transports very long-chain FAs (VLCFAs) from the cytosol into the peroxisome where the VLCFAs are degraded through β-
Externí odkaz:
https://doaj.org/article/7195fa710b5142e4a6d2da324487dc47
Autor:
Md. Matiur Rahman, Ryoka Nakanishi, Fumi Tsukada, Shigeo Takashima, Yoshiko Wakihara, Yuji O. Kamatari, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
Publikováno v:
Membranes, Vol 13, Iss 2, p 185 (2023)
This study aimed to identify a suitable RNA extraction kit and stable internal control microRNA (miRNA) in bovine milk small extracellular vesicles (sEVs) for a quantitative polymerase chain reaction (qPCR) analysis. Two RNA extraction kits, miRNeasy
Externí odkaz:
https://doaj.org/article/31407ecb53354d9db899c9856e1504f0
Autor:
Mami Hiraoka, Shigeo Takashima, Yoshiko Wakihara, Yuji O. Kamatari, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
Publikováno v:
Viruses, Vol 14, Iss 5, p 1022 (2022)
Enzootic bovine leukosis (EBL) is a disease caused by bovine leukemia virus (BLV); only a small percentage of BLV-infected cattle develop EBL and present with B-cell lymphosarcoma. There is no vaccine against BLV, treatment for EBL, or method for pre
Externí odkaz:
https://doaj.org/article/2d1a9fc283e540e0be38715e50fcd619
Autor:
Hiroki, Kawai, Shigeo, Takashima, Akiko, Ohba, Kayoko, Toyoshi, Kazuo, Kubota, Hidenori, Ohnishi, Nobuyuki, Shimozawa
Publikováno v:
Brain and Development. 45:58-69
Bile acid intermediates, 3α,7α,12α-trihydroxycholestanoic acid (THCA) and 3α,7α-dihydroxycholestanoic acid (DHCA), are metabolized in peroxisomes. Some peroxisomal disorders (PDs), such as Zellweger spectrum disorder (ZSD), show an accumulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990fcb4efa1d315e8147c7db79c01fdd
https://doi.org/10.1016/j.braindev.2022.10.001
https://doi.org/10.1016/j.braindev.2022.10.001
Autor:
Md. Matiur Rahman, Shigeo Takashima, Yuji O. Kamatari, Yassien Badr, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
Publikováno v:
Membranes, Vol 11, Iss 12, p 933 (2021)
Bovine milk small extracellular vesicles (sEVs) contain many biologically important molecules, including mRNAs. Quantitative real-time polymerase chain reaction (qRT-PCR) is a widely used method for quantifying mRNA in tissues and cells. However, the
Externí odkaz:
https://doaj.org/article/46f6d6fce4734aa282a5a5c7dcbc0e24