Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Shigeo, Uchino"'
Autor:
Hiroko Kotajima-Murakami, Hideo Hagihara, Atsushi Sato, Yoko Hagino, Miho Tanaka, Yoshihisa Katoh, Yasumasa Nishito, Yukio Takamatsu, Shigeo Uchino, Tsuyoshi Miyakawa, Kazutaka Ikeda
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by impairments in social interaction and restricted/repetitive behaviors. The neurotransmitter γ-aminobutyric acid (GABA) through GABAA receptor signaling in the i
Externí odkaz:
https://doaj.org/article/fb45d5df75794c268efd4f6bfc23725b
Autor:
Hiroko Kotajima-Murakami, Toshiyuki Kobayashi, Hirofumi Kashii, Atsushi Sato, Yoko Hagino, Miho Tanaka, Yasumasa Nishito, Yukio Takamatsu, Shigeo Uchino, Kazutaka Ikeda
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract The mammalian target of rapamycin (mTOR) signaling pathway plays a crucial role in cell metabolism, growth, and proliferation. The overactivation of mTOR has been implicated in the pathogenesis of syndromic autism spectrum disorder (ASD), su
Externí odkaz:
https://doaj.org/article/b779774794c04675b2ec24c51283d035
Autor:
Sari Kishikawa, Shintaro Sato, Satoshi Kaneto, Shigeo Uchino, Shinichi Kohsaka, Seiji Nakamura, Hiroshi Kiyono
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
M cells are intestinal epithelial cells that are specialized to transcytose antigens and bacteria from the intestinal lumen to antigen presenting cells on the other side. Here the authors show that the actin-binding protein Aif1 is highly expressed b
Externí odkaz:
https://doaj.org/article/e17e8cc71f784c73972babb092522de6
Autor:
Hiroko, Kotajima-Murakami, Hideo, Hagihara, Atsushi, Sato, Yoko, Hagino, Miho, Tanaka, Yoshihisa, Katoh, Yasumasa, Nishito, Yukio, Takamatsu, Shigeo, Uchino, Tsuyoshi, Miyakawa, Kazutaka, Ikeda
Publikováno v:
Frontiers in psychiatry. 13
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by impairments in social interaction and restricted/repetitive behaviors. The neurotransmitter γ
Autor:
Yasuhiro Funahashi, Rijwan Uddin Ahammad, Xinjian Zhang, Hossen Emran, Md. Omar Faruk, Huanhuan Wang, Minhua Wu, Yifan Xu, Daisuke Tsuboi, Tomoki Nishioka, Keisuke Kuroda, Mutsuki Amano, Kenji Sakimura, Shigeo Uchino, Kiyofumi Yamada, Taku Nagai, Kozo Kaibuchi
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:2-B
Autor:
Seiji Nakamura, Shigeo Uchino, Shinichi Kohsaka, Shintaro Sato, Satoshi Kaneto, Hiroshi Kiyono, Sari Kishikawa
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
M cells in follicle-associated epithelium (FAE) are specialized antigen-sampling cells that take up intestinal luminal antigens. Transcription factor Spi-B regulates M-cell maturation, but the molecules that promote transcytosis within M cells are no
Autor:
Miho Tanaka, Yukio Takamatsu, Kazutaka Ikeda, Toshiyuki Kobayashi, Hirofumi Kashii, Yoko Hagino, Shigeo Uchino, Atsushi Sato, Yasumasa Nishito, Hiroko Kotajima
Publikováno v:
IBRO Reports. 6:S463
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:1-SS
Autor:
Hirotsugu Asano, Masayuki Itoh, Shigeo Uchino, Akiko Tsuchiya, Yasuko Nakamura, Tomomi Sanagi, Chikako Waga, Yu-ichi Goto, Shinichi Kohsaka, Eri Suzuki
Publikováno v:
Journal of Neurochemistry. 128:280-293
SHANK3 is a synaptic scaffolding protein enriched in the post-synaptic density of excitatory synapses. Since several SHANK3 mutations have been identified in a particular phenotypic group of patients with autism spectrum disorder (ASD), SHANK3 is str
Autor:
Shinichi Kohsaka, Shigeo Uchino, John G. Parnavelas, Carina Hanashima, Yuko Gonda, William D. Andrews, Hidenori Tabata, Takashi Namba, Kazunori Nakajima
Publikováno v:
Cerebral Cortex. 23:1495-1508
Laminar organization is a key feature of the mammalian cerebral cortex, but the mechanisms by which final positioning and “inside-out” distribution of neurons are determined remain largely unknown. Here, we demonstrate that Robo1, a member of the