Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Shigenori WATANABE"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 94, Iss 1, Pp 39-44 (2004)
This experiment was designed to test the hypothesis that endogenous corticotropin-releasing factor (CRF) contributes to the neurodegenerative process following an ischemic insult. To test this hypothesis, the effects of chronic intracerebroventricula
Externí odkaz:
https://doaj.org/article/2fdd251340f941f88d737c2ac01637a3
Autor:
Takao, Shimazoe 1, Miyuki, Maetani 1, Sachiko, Nakamura 1, Shiro, Yamanouchi 1, Shigenori, Watanabe 1, Kyoko, Miyasaka 2, Akira, Kono 3, Akihiro, Funakoshi 3
Publikováno v:
In Japanese Journal of Pharmacology 1999 80(1):85-88
Autor:
Kiyoshi Matsumoto, Shigenori Watanabe
Publikováno v:
The Journal of The Institute of Electrical Engineers of Japan. 128:36-39
Publikováno v:
Neuroscience Letters. 431:66-70
We investigated the mechanism underlying the anxiolytic actions of the neuropeptide nociceptin/orphanin FQ (N/OFQ) using the elevated plus-maze test and T-maze test. Microinfusions of N/OFQ (10 or 32pmol) into the central amygdala (ACE) increased the
Autor:
Takahiro J. Nakamura, Shizufumi Ebihara, Shin Inoue, Shigenori Watanabe, Kazuyuki Shinohara, Takahiro Moriya, Takao Shimazoe
Publikováno v:
Journal of Neuroscience Research. 82:622-630
Although it has long been established that estrogen alters circadian rhythms in behavior, physiology, and reproductive functions in mammals, the molecular mechanism for these effects remains unknown. To explore the possibility that estrogen affects c
Publikováno v:
Neuropharmacology. 46:1195-1200
The aim of the present study is to clarify the possible relevance of the arachidonic acid cascade to working memory in rats, by using a three-panel runway apparatus. Interleukin-1 beta, injected bilaterally into the dorsal hippocampus at a dose of 10
Publikováno v:
Journal of Neurochemistry. 88:148-154
We have previously shown that behavioral changes induced by cannabinoid were due to an elevation of prostaglandin E2 (PGE2) via the arachidonic acid cascade in the brain. In the present study, we investigated the participation of the prostanoid EP3 r
Publikováno v:
Journal of Neurophysiology. 90:1662-1670
GABAergic afferent inputs are thought to play an important role in the control of the firing pattern of substantia nigra pars compacta (SNc) dopaminergic neurons. We report here the actions of presynaptic kainite (KA) receptors in GABAergic transmiss
Autor:
Takashi Tsuruo, Chen Jiang, Noriko Koyabu, Mikihiko Naito, Yoshikazu Yonemitsu, Shigenori Watanabe, Takao Shimazoe, Yasufumi Sawada, Hisakazu Ohtani
Publikováno v:
Human Gene Therapy. 14:1181-1191
The gene encoding mouse glial cell-derived neurotrophic factor (mGDNF gene) was transfected into brain capillary endothelial cells (BCECs) with the aim of delivering the gene product extensively into the brain parenchyma by making use of the secretor
Publikováno v:
Journal of Neurochemistry. 82:234-239
In this study, we examined the effects of a 105 amino acid carboxyl terminal fragment of beta-amyloid precursor protein (CT105) and inflammatory cytokines on working memory in rats, by using a three-panel runway set-up. CT105 at 10 nmol/side signific