Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Shigenori Ogata"'
Autor:
Yoshio Misumi, Shigenori Ogata, Shotaro Sakisaka, Shinichi Hirose, Yukio Ikehara, Kimimitsu Oda, Miwa Sohda
Publikováno v:
Biochemical and Biophysical Research Communications. 456:275-281
p230/golgin-245 is a trans-Golgi coiled-coil protein that is known to participate in regulatory transport from the trans-Golgi network (TGN) to the cell surface. We investigated the role of p230 and its interacting protein, microtubule actin crosslin
Autor:
Shigenori Ogata, Yukio Takano, Masako Koguchi, Yasutoshi Hirabara, Fumito Kobayashi, Keisuke Migita, Kenji Honda, Kohei Koga, Kyoko Nakajima
Publikováno v:
Biological and Pharmaceutical Bulletin. 30:990-993
In this paper, we directly demonstrate, for the first time, the activation of Ca(2+)-dependent protein kinase C (PKC) in the spinal cord of diabetic mice. In streptozotocin (STZ)-treated (200 mg/kg, i.v.) diabetic mice, hypersensitivity (allodynia) t
Autor:
Miwa Sohda, Yoshio Misumi, Nobutaka Kiyokawa, Shigenori Ogata, Shotaro Sakisaka, Junichro Fujimoto, Shin-ichiro Yoshimura, Nobuhiro Nakamura, Yukio Ikehara, Takami Fusano
Publikováno v:
Biochemical and Biophysical Research Communications. 338:1268-1274
Depletion of p115 with small interfering RNA caused fragmentation of the Golgi apparatus, resulting in dispersed distribution of stacked short cisternae and a vesicular structure (mini-stacked Golgi). The mini-stacked Golgi with cis- and trans-organi
Autor:
Akio Kinoshita, Kikuo Arakawa, Keita Noda, Emiko Tsuji, Shigenori Ogata, Munehito Ideishi, Manabu Sasaguri, Manabu Koga
Publikováno v:
Immunopharmacology. 44:15-19
We previously purified a kallikrein-like enzyme from the dog heart and demonstrated that it is not only able to form kinins but can also convert angiotensin (Ang) I to Ang II. The aim of the present study was to clarify the structure and tissue local
Autor:
Shigenori Ogata, Hirokazu Maeda, Manabu Sasaguri, Keita Noda, Akio Kinoshita, Kikuo Arakawa, Emiko Tsuji, Munehito Ideishi
Publikováno v:
Journal of Hypertension. 15:675-682
Objective To purify and characterize a kinin-forming enzyme in the dog heart and to examine the ability of this enzyme to generate angiotensin (Ang) II from Ang I. Methods The enzyme was isolated from heart homogenate using a diethylaminoethyl-Sephar
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1141:245-252
Two diabetes-inducible forms of cytochrome P-450, named P-450ST-1 and -ST-2, were purified from the liver microsomes of streptozotocin-diabetic male rats by sodium cholate solubilization, octylamino-Sepharose 4B chromatography and high-performance li
Autor:
Nobuhiro Nakamura, Yoshio Misumi, Shigenori Ogata, Shinichi Hirose, Shotaro Sakisaka, Akitsugu Yamamoto, Kimimitsu Oda, Yukio Ikehara, Miwa Sohda
Publikováno v:
Traffic (Copenhagen, Denmark). 11(12)
The coiled-coil Golgi membrane protein golgin-84 functions as a tethering factor for coat protein I (COPI) vesicles. Protein interaction analyses have revealed that golgin-84 interacts with another tether, the conserved oligomeric Golgi (COG) complex
Publikováno v:
Biochemical and biophysical research communications. 397(3)
So far, the content and accumulation of ATP in isolated endoplasmic reticulum (ER) are little understood. First, we confirmed using electron microscopic and Western blotting techniques that the samples extracted from MDCK cells are endoplasmic reticu
Autor:
Shigenori Ogata, Yoshio Misumi, Noboru Takami, Emiko Tsuji, Yukio Ikehara, Toshiyuki Fujiwara
Publikováno v:
Biochemistry. 31:11921-11927
Dipeptidyl peptidase IV (DPPIV), a serine protease expressed on the cell surface, is deficient in a Fischer rat substrain. Northern blot analysis showed no difference in the size and amount of DPPIV mRNA between normal (344/NC) and deficient (344/CRJ
Publikováno v:
Biochemical Journal. 276:337-342
A cDNA clone (lambda MC-2) for contrapsin, a serine-proteinase inhibitor, was isolated from a lambda ZAP mouse liver cDNA library. The 1.6 kb cDNA insert of lambda MC-2 contained an open reading frame that encodes a 418-residue polypeptide (46,970 Da