Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Shigemitsu Ohsawa"'
1
Geranylgeraniol Causes a Decrease in Levels of Calreticulin and Tyrosine Phosphorylation of a 36-kDa Protein Prior to the Appearance of Apoptotic Features in HL-60 Cells
Autor: Shigemitsu Ohsawa, Yutaka Masuda, Mitsuru Okamoto, Shigeo Nakajo, I. Sakai, Kazuyasu Nakaya
Publikováno v: Biochemical and Biophysical Research Communications. 226:741-745
It was demonstrated recently that geranylgeraniol (GGO) has potent apoptosis-inducing activity in various lines of tumor cells, including HL-60 cells. In the present study, we found that GGO markedly inhibited the expression of a calcium-binding prot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52c95b4a21f9c6ee3c58274ac9515b8
https://doi.org/10.1006/bbrc.1996.1423
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2
Novel Role of Vitamin K2: A Potent Inducer of Differentiation of Various Human Myeloid Leukemia Cell Lines
Autor: S Hashimoto, T. Hida, Shigemitsu Ohsawa, I. Sakai, M. Yoda, Shigeo Nakajo, Kazuyasu Nakaya
Publikováno v: Biochemical and Biophysical Research Communications. 205:1305-1310
When myeloblastic ML1 cells were cultured in the presence of Vitamin K 2 (menaquinone, VK 2 ), the population of cells capable of reducing NBT increased to 83.5% at low VK 2 concentration of 1 μM, indicating VK 2 induces cellular differentiation. VK
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552093bec1b998b720d6bbd678309ed9
https://doi.org/10.1006/bbrc.1994.2807
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4
Absorption of d-α-Tocopherol Solubilized in Micellar Solutions of Various Bile Salts by Rat Small Intestine
Autor: Yoshiaki Wakayama, Noritoshi Koyama, Seiji Suzuki, Shuichi Nagakura, Hiroki Itoh, Yukiyoshi Jyonoshita, Minoru Ueno, Yuki Tsushima, Shigemitsu Ohsawa
Publikováno v: Journal of Japan Oil Chemists' Society. 40:400-405
The solubilization of d-α-tocopherol (VE) in micellar solutions of various bile salts, mean aggregation numbers of the micelles, and absorption of VE from each micellar solution in rat small intestine were studied. The micellar solutions were prepar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db7afcd6fbb3e6103274f9c2ae2d7cf8
https://doi.org/10.5650/jos1956.40.400
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5
Evaluation of phase transition temperature of liposomes by using the tautomerism of α-Benzoylacetoanilide
Autor: S. Katoh, E. Tomoyama, N. Koyama, S. Kobayashi, Shigemitsu Ohsawa, Yutaka Morita, Minoru Ueno
Publikováno v: Journal of Colloid and Interface Science. 134:589-592
The phase transition temperatures for liposomes of dipalmitoyl- and distearoylphosphatidylcholines (abbreviated here as DPPC and DSPC) and for the other liposomes containing small amounts of soybean oil in the bilayer were determined from the changes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53380cac6bb9bcc7b8291ac19f8336a2
https://doi.org/10.1016/0021-9797(90)90167-m
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6
Geranylgeraniol Is a Potent Inducer of Apoptosis in Tumor Cells
Autor: Hidekazu Ohizumi, Yutaka Masuda, Kazuyasu Nakaya, Shigeo Nakajo, Shigemitsu Ohsawa, I. Sakai
Publikováno v: The Journal of Biochemistry. 117:11-13
We screened various isoprenoids to find inducers of apoptosis for human leukemia HL-60 cells, and found that GGO (geranylgeraniol) had the most potent apoptosis-inducing activity, as judged from DNA fragmentation in HL-60 cells. The apoptosis-inducin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c67a3959a945c4d0cf93fe46d18d022
https://doi.org/10.1093/oxfordjournals.jbchem.a124695
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10
Effect of Coenzyme Q10 and Other Additives on the Stability and the Size Distribution of Liposome obtained by Ethanol Injection Method
Autor: Minoru Ueno, Kohichi Shibusawa, Shigemitsu Ohsawa, Hiroshi Kikuchi, Shinji Katoh
Publikováno v: Journal of Japan Oil Chemists' Society. 36:272-275
Single bilayer liposomes (SUV type) were obtained from an ethanol solution of egg licithin. Co-enzyme Q10 (CoQ10), used for treating heart disease, was incorporated into the liposomes. Liposome stability and effects of various additives (Polyethylene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21b42036afd5e27b5ed8c6168872af2a
https://doi.org/10.5650/jos1956.36.272
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