Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shigemi Kinoshita"'
Autor:
Sarah Black, Christian M. Schürch, Darci J. Phillips, Yury Goltsev, Janos Demeter, Garry P. Nolan, Nikolay Samusik, Inti Zlobec, Graham L. Barlow, Pauline Chu, Luca Noti, Salil S. Bhate, David R. McIlwain, Shigemi Kinoshita
Publikováno v:
Cell
Schürch, Christian M; Bhate, Salil S; Barlow, Graham L; Phillips, Darci J; Noti, Luca; Zlobec, Inti; Chu, Pauline; Black, Sarah; Demeter, Janos; McIlwain, David R; Kinoshita, Shigemi; Samusik, Nikolay; Goltsev, Yury; Nolan, Garry P (2020). Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front. Cell, 182(5), 1341-1359.e19. Cell Press 10.1016/j.cell.2020.07.005
Schürch, Christian M; Bhate, Salil S; Barlow, Graham L; Phillips, Darci J; Noti, Luca; Zlobec, Inti; Chu, Pauline; Black, Sarah; Demeter, Janos; McIlwain, David R; Kinoshita, Shigemi; Samusik, Nikolay; Goltsev, Yury; Nolan, Garry P (2020). Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front. Cell, 183(3), p. 838. Cell Press 10.1016/j.cell.2020.10.021
Schürch, Christian M; Bhate, Salil S; Barlow, Graham L; Phillips, Darci J; Noti, Luca; Zlobec, Inti; Chu, Pauline; Black, Sarah; Demeter, Janos; McIlwain, David R; Kinoshita, Shigemi; Samusik, Nikolay; Goltsev, Yury; Nolan, Garry P (2020). Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front. Cell, 182(5), 1341-1359.e19. Cell Press 10.1016/j.cell.2020.07.005
Schürch, Christian M; Bhate, Salil S; Barlow, Graham L; Phillips, Darci J; Noti, Luca; Zlobec, Inti; Chu, Pauline; Black, Sarah; Demeter, Janos; McIlwain, David R; Kinoshita, Shigemi; Samusik, Nikolay; Goltsev, Yury; Nolan, Garry P (2020). Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front. Cell, 183(3), p. 838. Cell Press 10.1016/j.cell.2020.10.021
Summary Antitumoral immunity requires organized, spatially nuanced interactions between components of the immune tumor microenvironment (iTME). Understanding this coordinated behavior in effective versus ineffective tumor control will advance immunot
Autor:
Kayoko Matsunaga, Minehiro Okuda, Masatoshi Ito, Hirofumi Kuwahara, Isao Yoshimura, Yuko Okamoto, Fukuyoshi Mori, Shigemi Kinoshita, Keiichi Kawai, Hajime Kojima, Mariko Sugiyama, Kumiko Washizaki, Hirohiko Akamatsu, Norito Katoh, Masaru Natsuaki, Hiromi Kanto
Publikováno v:
The Journal of Dermatology. 40:363-369
We investigated the optimum application for evaluating skin irritation response by using samples of irritants commonly used as additives in cosmetics and other common household products. We studied 47 volunteers (16 men and 31 women). We selected thr
Autor:
Shigemi Kinoshita, Shunji Natsuka, Yukihiro Nishio, Shigeru Hashimoto, Hiroshi Isshiki, Toshihiro Nakajima, Tadamitsu Kishimoto, Shizuo Akira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8de1184175e0b1d9d04837efa64512
https://doi.org/10.1159/000420763
https://doi.org/10.1159/000420763
Autor:
Gina C. Jager, Sharon South, Chris Murriel, Shigemi Kinoshita, Garry P. Nolan, Jacqueline McBride, Dennis J. Mitchell, Omar D. Perez, L. A. Herzenberg
Publikováno v:
Nature Immunology. 4:1083-1092
Leukocyte functional antigen 1 (LFA-1), with intercellular adhesion molecule ligands, mediates T cell adhesion, but the signaling pathways and functional effects imparted by LFA-1 are unclear. Here, intracellular phosphoprotein staining with 13-dimen
Autor:
Garry P. Nolan, Omar D. Perez, Toshio Kitamura, James Lorens, Donald G. Payan, Yasumichi Hitoshi, Shigemi Kinoshita
Publikováno v:
Immunity. 16(1):51-65
We identified intracellular adhesion molecule-2 (ICAM-2) in a genetic screen as an activator of the PI3K/AKT pathway leading to inhibition of apoptosis. ICAM-2 induced tyrosine phosphorylation of ezrin and PI3K kinase membrane translocation, resultin
Autor:
Huijun Z. Ring, Shinichi Kitada, Yasumichi Hitoshi, James Lorens, Garry P. Nolan, Uta Francke, Shigemi Kinoshita, Mark A. LaBarge, Joan M. Fisher, John C. Reed
Publikováno v:
Immunity. 8(4):461-471
Fas is a surface receptor that can transmit signals for apoptosis. Using retroviral cDNA library–based functional cloning we identified a gene toso, that blocks Fas-mediated apoptosis. Toso expression was confined to lymphoid cells and was enhanced
Autor:
Atsushi Miyajima, Garry P. Nolan, Shigemi Kinoshita, Toshio Kitamura, Akira Shibuya, Mayumi Onishi
Publikováno v:
Proceedings of the National Academy of Sciences. 92:9146-9150
Expression cloning of cDNAs was first described a decade ago and was based on transient expression of cDNA libraries in COS cells. In contrast to transient transfection of plasmids, retroviral gene transfer delivers genes stably into a wide range of
Autor:
Akira Ishiko, Hiroshi Ohshima, Shigemi Kinoshita, Hirotsugu Takiwaki, Mikayo Futagawa, Midori Oyobikawa, Hiromi Kanto
Publikováno v:
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). 19(1)
Background/aim: The decrease of skin elasticity on the cheek is a major concern to woman. The Cutometer has been widely used to evaluate skin elasticity and its change with aging. Cutometer parameters derived from one suction have been traditionally
Autor:
Shizuo Akira, Tatsuru Sasagawa, Shigemi Kinoshita, Koichi Sasaki, Tadamitsu Kishimoto, Masanobu Naruto, Toshihiro Nakajima
Publikováno v:
Proceedings of the National Academy of Sciences. 90:2207-2211
NF-IL6, a member of the basic leucine zipper (bZIP) family transcription factors, is involved in expression of inducible genes involved in immune and inflammatory responses. We observed that coexpression of oncogenic p21ras stimulated the transactiva
Autor:
Shizuo Akira, Yukihiro Nishio, Osamu Tanabe, Toshihiro Nakajima, Shigemi Kinoshita, Takahisa Sugita, Hiroshi Isshiki, Toshio Hirano, Tadamitsu Kishimoto
Publikováno v:
The EMBO Journal. 9:1897-1906
NF-IL6 is a nuclear factor that specifically binds to an IL1-responsive element in the IL-6 gene. In this study the gene encoding NF-IL6 has been cloned by direct screening of a lambda gt11 library using NF-IL6 binding sequence as a ligand. The full-