Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shigemi Hayashi"'
Autor:
Josien Levenga, Shigemi Hayashi, Femke M.S. de Vrij, Sebastiaan K. Koekkoek, Herma C. van der Linde, Ingeborg Nieuwenhuizen, Cheng Song, Ronald A.M. Buijsen, Andreea S. Pop, Baltazar GomezMancilla, David L. Nelson, Rob Willemsen, Fabrizio Gasparini, Ben A. Oostra
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 3, Pp 311-317 (2011)
Fragile X syndrome, the most common form of inherited intellectual disability, is caused by a lack of FMRP, which is the product of the Fmr1 gene. FMRP is an RNA-binding protein and a component of RNA-granules found in the dendrites of neurons. At th
Externí odkaz:
https://doaj.org/article/2805dc9459cd4a9eb1549444b3d8d9c4
Autor:
Scott R. Hutton, Larysa H. Pevny, Olena Taranova, Shigemi Hayashi, Mahendra S. Rao, Andrew P. McMahon, B. Matthew Fagan, Scott T. Magness, Pam Ellis
Publikováno v:
Developmental Neuroscience. 26:148-165
Multipotent neural stem cells are present throughout the development of the central nervous system (CNS), persist into adulthood in defined locations and can be derived from more primitive embryonic stem cells. We show that SOX2, an HMG box transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3847c772d0ef73d5e8baf8bd04d79ccd
https://doi.org/10.1159/000082134
https://doi.org/10.1159/000082134
Publikováno v:
Mechanisms of Development. 119:S97-S101
We have generated a transgenic line that expresses the Cre gene product under the regulation of a 12.5 kb upstream regulatory sequence from the Sox2 gene. Using a R26R reporter line, we show that this transgenic line induces recombination in all epib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55ace6e1293120d2dbdfdca4369d0cf
Publikováno v:
Gene Expression Patterns. 2:93-97
We have generated a transgenic line that expresses the Cre gene product under the regulation of a 12.5 kb upstream regulatory sequence from the Sox2 gene. Using a R26R reporter line, we show that this transgenic line induces recombination in all epib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f10f53ab3c016373164ae861e8c0a91f
https://doi.org/10.1016/s0925-4773(02)00292-7
https://doi.org/10.1016/s0925-4773(02)00292-7
Autor:
Andrew P. McMahon, Shigemi Hayashi
Publikováno v:
Developmental Biology. 244(2):305-318
In recent years, the Cre integrase from bacteriophage P1 has become an essential tool for conditional gene activation and/or inactivation in mouse. In an earlier report, we described a fusion protein between Cre and a mutated form of the ligand bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469241322fb5d145325af51286a800b2
Autor:
Arnold J. Levine, Brian Souza, Paul Polakis, Shigemi Hayashi, Bonnee Rubinfeld, Eric Wieschaus
Publikováno v:
Proceedings of the National Academy of Sciences. 94:242-247
Mutations in the adenomatous polyposis coli gene (which encodes a protein called APC) are associated with the formation of intestinal polyps and colon cancers. To facilitate the functional study of APC we have isolated its Drosophila homolog (D-APC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c94af071062fa5bf32ee8e2c16c98f
https://doi.org/10.1073/pnas.94.1.242
https://doi.org/10.1073/pnas.94.1.242
Publikováno v:
genesis. 37:51-53
Summary: The Sox2 gene is expressed in several undifferentiated cell types. In an earlier study we described a Sox2Cre transgene that mediates epiblast-specific Cre-mediated modification of gene activity in the embryo. Here we report that this transg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ad73cd37dcb3565ba3d0c0cce49056
https://doi.org/10.1002/gene.10225
https://doi.org/10.1002/gene.10225
Autor:
Femke M.S. de Vrij, Sebastiaan K. E. Koekkoek, Fabrizio Gasparini, Rob Willemsen, Ronald A.M. Buijsen, Shigemi Hayashi, Ingeborg M. Nieuwenhuizen, Baltazar Gomez-Mancilla, Cheng Song, Josien Levenga, Andreea S. Pop, Ben A. Oostra, Herma C. van der Linde, David L. Nelson
Publikováno v:
Neurobiology of Disease, 42(3), 311-317. Academic Press
Neurobiology of Disease, Vol 42, Iss 3, Pp 311-317 (2011)
Neurobiology of Disease, Vol 42, Iss 3, Pp 311-317 (2011)
Fragile X syndrome, the most common form of inherited intellectual disability, is caused by a lack of FMRP, which is the product of the Fmr1 gene. FMRP is an RNA-binding protein and a component of RNA-granules found in the dendrites of neurons. At th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106bf4af143e1c2ddd7f3e21b0a240bf
https://pure.eur.nl/en/publications/166a51fe-2181-45ce-8735-e34b6313bda8
https://pure.eur.nl/en/publications/166a51fe-2181-45ce-8735-e34b6313bda8
Autor:
Shigemi Hayashi, Mansuo L. Hayashi
Publikováno v:
Principles and Practice ISBN: 9783540284154
With the deciphering of the human genome, a major challenge is to determine the function for each of the estimated 30,000 genes in the physiology and patho-physiology of various organs. Using the mouse as a model system, this has been achieved by new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1c8510fc0dc281de23a70e5d1901a80
https://doi.org/10.1007/978-3-540-28489-5_6
https://doi.org/10.1007/978-3-540-28489-5_6
Autor:
Kirk R. Thomas, Mario R. Capecchi, Jeffery R. Barrow, Andrew P. McMahon, William D. Howell, Michael Rule, Shigemi Hayashi
Publikováno v:
Developmental biology. 312(1)
The establishment of anteroposterior (AP) polarity in the early mouse epiblast is crucial for the initiation of gastrulation and the subsequent formation of the embryonic (head to tail) axis. The localization of anterior and posterior determining gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f5385a00db2eb0ea723c26aa06f3d2
https://pubmed.ncbi.nlm.nih.gov/18028899
https://pubmed.ncbi.nlm.nih.gov/18028899